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Article | IMSEAR | ID: sea-202731

ABSTRACT

Introduction: Hypoparathyroidism is a rare endocrinedisorder characterized by low serum calcium and parathyroidhormone levels. The most common cause is iatrogenic surgicalremoval. However, idiopathic primary hypoparathyroidismis to be kept in mind especially in children as a cause ofhypoparathyroidism. Since PTH is important in calciumhomeostasis, this condition may cause ectopic calcifications,including intra cerebral calcifications, though rare.Case report: 11 year old MCH,with history of birth asphyxiaand global developmental delay was presented to emergencywith seizures. The child had seizures since the age of 5years,and wasn’t on regular treatment. The patient was admittedwith a provisional diagnosis of Cerebral Palsy with seizuredisorder with polymorphic seizures was made and treatedconservatively. Neuroimaging showed bilateral symmetriccalcification in basal ganglia,thalami and capsule. A completeworkup showed low serum calcium, high serum phosphorusand low parathormone. Calcium supplementation was givenand seizures was made under control.Conclusion: Idiopathic hypoparathroidism, though rarely, asit was in our case, may cause exuberant cerebral presentationswith extensive intracranial calcifications and extremehypocalcemia which may or may not correlate with severity ofsymptoms. Not only this is a treatable disorder that may havedangerous implications if untreated, but also its symptomsmay be completely reversed with prompt treatment.

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