Subject(s)
Eye/pathology , Humans , Leprostatic Agents/therapeutic use , Leprosy, Lepromatous/drug therapy , Male , Middle AgedSubject(s)
Female , Humans , Leprostatic Agents/therapeutic use , Leprosy/drug therapy , Male , RecurrenceABSTRACT
Eyes of 237 multibacillary leprosy patients on Multi Drug Therapy were studied for a minimum period of 2 years and maximum period of 4 years. Ocular status remained unaltered in 75%, improved in 16% and there was worsening in 9% during the study period. The changes in those worsened were of microscopic nature and seen mostly among those with long duration of disease and among reactors.
Subject(s)
Adolescent , Adult , Drug Therapy, Combination , Eye/pathology , Eye Infections, Bacterial/drug therapy , Female , Humans , Leprosy/drug therapy , Male , Middle AgedABSTRACT
3 cases of renal toxicity to Rifampicin are reported. All cases recovered following therapy, two required haemodialysis. It is important that cases on Rifampicin be monitored for renal toxicity and appropriate measures taken in time to prevent a fatal outcome, if detected.
Subject(s)
Adult , Aged , Drug Therapy, Combination , Female , Humans , Acute Kidney Injury/chemically induced , Leprosy/drug therapy , Male , Rifampin/adverse effectsABSTRACT
Thirtyfour cases of Borderline Reaction were treated with Clofazimine and corticosteroids. The clinical findings including sensory and motor assessments and skin smears were made before treatment and again when the reaction subsided, subject to a minimum period of one year. These findings are analysed and discussed.