ABSTRACT
Background: developmental delay occurs when a child exhibits a significant delay in the acquisition of milestones or skills, in one or more domains of development [i.e., gross motor, fine motor, speech/language, cognitive, personal/social, or activities of daily living]
Aim of the work: the present study aimed to investigate the most common risk factors of delayed development in children under four years attending Sohag General Hospital
Subjects and Methods: a case control study was conducted in Sohag General Hospital during the period from January 2015 to June 2016 on children attending Pediatric, Physiotherapy and Phoniatric clinics in Sohag General Hospital, Sohag Governorate. The sample size was 150 cases and 150 controls. One hundred and fifty children [aged 1.5 month to 48 months] diagnosed with developmental delay by a specialist or/and a developmental pediatrician were recruited as cases
Results: in the logistic regression model, the odds of developing delayed milestones is significantly higher among children with cyanosis [OR=16.391], low birth weight [OR=6.147], parental consanguinity [OR=5.489], 1st birth order [OR=4.048], urban residence [OR=3.702] and history of neonatal jaundice [OR=2.518]
Conclusion: the urban children, first children and from few number of family members were more frequently at risk for developmental delay
ABSTRACT
Background: Many studies have discussed the relationship between breastfeeding and certain social, psychological and demographic variables.
Aims: The aim of this study was to determine the effect of social, psychological and demographic variables on breastfeeding among Kuwaiti mothers.
Methods: The total of 712 married women were selected who answered a questionnaire. Questions were asked about duration of breastfeeding and bottle feeding, degree of spousal relationship, religious sect and background. Religiosity, family stability and general health self-rating scales were used.
Results: Women who came from urban roots and consanguineous marriages had a higher mean duration of breastfeeding than those who came from Bedouin roots and nonconsanguineous marriages. There was a significant difference among the three maternal age groups in the duration of breastfeeding. A significant relationship was found between the duration of breastfeeding and all social, psychological and demographic variables except general health. Correlations were found between the duration of breastfeeding and maternal and paternal education, maternal occupation, years of marriage, age at marriage, family stability scale, self-esteem scale, and socioeconomic variables. The duration of artificial feeding, number of abortions, degree of religiosity, family stability scale, age, and socioeconomic scale related to the duration of the mother's breastfeeding.
Conclusions: Education plays an important role in affecting women's health in general and breastfeeding practice in particular
Subject(s)
Humans , Female , Adult , Sociological Factors , Demography , Psychology , Bottle Feeding , Surveys and QuestionnairesABSTRACT
Background: Interleukin-10 (IL-10) and IL–12B single nucleotide polymorphisms (SNPs) are confirmed to influence the natural history of hepatitis C virus (HCV) infection, and the response to treatment. This work aimed at evaluating the impact of SNPs in IL-10 gene at positions _1082, _819, and_592 and IL-12B gene on the response to the standard of care (SOC) treatment in Egyptian patients with chronic HCV. Methods: Eighty seven patients with chronic HCV treated by SOC therapy and 20 healthy controls were tested for SNPs in IL-10 at _1082 G/A, _819 C/T and_592 C/A and in IL- 12B (30-UTR 1188-A/C) by polymerase chain reaction (PCR). Patients were divided according to their virologic response into 2 groups; group Ι=patients who achieved sustained virologic response (SVR) and group Π = non responder (NR) patients. Results: SNPs of IL-10 at _1082 G/A and_819 C/T showed that; GA and TT genotypes were significantly related to SVR (P=0.001 and 0.007 respectively). IL-12 genepolymorphisms showed that; CC genotype was significantly related to SVR group (P=0.01) while AA genotype was significantly related to NR (P=0.01). Conclusions: Studying SNPs of IL-10_1082 G/A, IL-10_819 C/T and IL-12B (30-UTR 1188-C/A) proved GA, TT and CC genotypes, respectively, to be good predictors for SVR. Conversely, SNPs of IL-12 C/A proved AA genotype to be good predictor for NR.