ABSTRACT
Carpal tunnel syndrome [CTS] is a disorder of the hand which results from compression of the median nerve within its fibro-osseous tunnel at the wrist. The slowing in the forearm motor conduction velocity suggests the presence of retrograde degeneration. Existing studies conflict regarding a correlation between the seventies of the entrapment neuropathy in CTS and slowing of median motor nerve conduction velocity in the forearm. The objective of this work was to study retrograde degeneration [RGD] of the median nerve forearm segment in patients with CTS and its relation to variable severity of CTS in Egyptian patients. Twenty-four patients with CTS were included in this study. The Forearm mixed nerve conduction is presumed to be indicative of the conduction of the median nerve over the forearm and is used widely to assess causes of slowing forearm conduction velocity in CTS. In addition to conventional nerve conduction studies of the upper limb, forearm median mixed conduction studies were performed Median motor forearm amplitudes and nerve