ABSTRACT
Background: The objective of this study was to compare the safety and efficacy of tiotropium bromide with salbutamol in moderate persistent cases of bronchial asthma at tertiary care hospital. Methods: This was an open label, randomized parallel group study done in Government General Hospital, Srikakulam for a period of 12 weeks. Group-1 was given tiotropium bromide metered dose inhalational therapy 18mcg once daily in 50 patients. Group-2 was given salbutamol metered dose inhalational therapy 100mcg thrice daily in 30 patients. Results: Symptomatic improvement was observed in l two groups. At end point, mean FEV1 in tiotropium bromide treatment group improved by 149.96% compared with 135.16% salbutamol treatment group. At end point, mean FVC value in tiotropium bromide treatment group improved by 145.71% compared with 122.34% in salbutamol group. Mean FEV1 / FVC also improved by 155.41% in tiotropium bromide group compared with 105.41 % in salbutamol group. Conclusion: The present study proved tiotropium provide superior safety and efficacy relative to control drug in bronchial asthma patients in both clinical assessment score and spirometrically.
ABSTRACT
40 Anemic individuals aged between 15-40 years randomly were taken as subjects. They were trained for Trikonasana and its variations, Sarvangasana, Surya namaskara, Yoga mudras for 90 days under supervision of professional yoga trainers. Assessments of various parameters like Pulse rate, B.P, Hb%, were done before the training and after the training of 30th, 60th and 90th day with and without treatment. After yoga with treatment increases Pulse rate and Hb%, while BP was shown normal.