ABSTRACT
Background: To evaluate the agreement in intraocular pressure [IOP] measurements by Ocular Response Analyzer [ORA] and Tono-Pen XL [TXL] with the Goldmann Applanation Tonometer [GAT] and to examine corneal biomechanical properties in aphakic glaucoma patients with a central corneal thickness [CCT] >600 micro
Methods: Thirty-six eyes of aphakic glaucoma patients [group 1] and 40 eyes of normal children [group 2] were studied. The mean ORA and TXL IOP values were compared with the GATIOP values. Regression analyses were used to evaluate the associations between IOP and CCT, corneal hysteresis [CH], and corneal resistance factor [CRF]. Bland-Altman plots were used to evaluate the agreement between the tonometers
Results: The mean +/- standard deviations of the age and male/ female ratio were 16.58 +/- 5.44 and 15.75 +/- 5.04 years and 14/22 and 18/22 in group 1 and group 2, respectively. CCT in group 1 was 651.1 +/- 42 and in group 2 was 567.3 +/- 32.4. In group 1, the mean TXL [22.4, P=0.004], IOPcc [corneal compensated] [27.8, P=0.005], and IOPg [Goldmann correlated] values [28.1, P<0.0001] were greater than GAT-IOP [20.6]. In group 2, only IOPg value [16.4] was higher than GAT-IOP [14.8, P=0.04]. IOP reading of all the tonometers were positively and negatively associated with CRF and CH in the multiple regression analysis, respectively
Conclusion: The TXL had a greater agreement with the GAT, and the ORA overestimated IOP in aphakic glaucoma patients. The ORA and TXL seemed to be affected by CH and CRF
ABSTRACT
To evaluate the clinical and epidemiological characteristics of children with ocular trauma. We retrospectively reviewed the medical records of 278 children [aged 15 years or less] hospitalized with ocular injuries and treated as inpatients at a tertiary referral center in Shiraz, Iran, from 2005 to 2008. Nominal variables were evaluated with a Chi-square test. A P-value less than 0.05 indicated statistical significance. The cohort was comprised of 205 [74%] males, outnumbering females by a ratio of 2.81/1. The mean age was 7.6 +/- 3.96 years. Rural residents comprised 125 [45%] of the cohort. Sharp objects caused ocular injury in 211 [76%] cases, and 207 [74%] cases had open-globe injuries. The lens was injured in 62 [30%] cases at initial examination and 89 [43%] patients according to ultrasound examination [P = 0.006]. Twenty-eight cases [10%] developed post-traumatic endophthalmitis. Endophthalmitis was associated with needle injury [odd ratio [OR] = 19.25] and presence of intraocular foreign body [OR = 3.48]. Visual acuity of patients with closed-globe injuries was 20/200 or better on both initial and final examinations. Visual acuity of patients with open-globe injuries were in the range of light perception to 20/200. Trauma is an important cause of childhood ocular morbidity in southern Iran. Playing with sharp objects is an important cause of ocular trauma in children, and most injuries can be prevented by careful supervision