ABSTRACT
Background: Neuroimaging is indicated in most instances of new-onset myelopathy for clinico-radiological correlation in terms of diagnosis, recovery, and prediction of recurrence. Aim: This study was conducted to study the clinical profile of cases of Compressive Myelopathy and the pattern of spinal cord involvement, also to compare the sites of localisation of clinical diagnosis with MRI diagnosis. Methodology: The present study was a prospective study involving 30 patients. Patients with clinical suspicion of spinal cord disease of age group 20-80 years were included as study participants. The primary pulse sequences included T1 and T2 weighted images on MRI, the location of the lesion, its margins, signal intensity on both T1 and T2 weighted images was noted. Results: The majority of 53.33% of participants were aged between 51 to 60 years. Difficulty in walking was observed in 97% of participants. Men were more often affected than women. Cervical spondylosis was the commonest cause of compressive myelopathy in 57%. A most common pattern of spinal cord involvement was combined Anterior + Posterior cord involvement. The cervical site of localisation (54%) was the commonest followed by the thoracic and lumbar spinal cord. Conclusion: Myelopathies have male preponderance. The commonest cause of compressive myelopathy was Cervical spondylosis. Anterior plus posterior cord syndrome was the commonest pattern seen, followed by posterior cord syndrome, anterior cord syndrome being the least observed. MRI correlates well with a clinical diagnosis and is useful in suggesting the location of the lesion.
ABSTRACT
Background: Colorectal diseases are frequently encountered in clinical practice. They range from minor problems causing minimal discomfort to potentially serious diseases causing much morbidity and mortality. Clinically most of these disorders present with non-specific symptoms like altered bowel habits, diarrhea, bleeding per rectum either melaena or fresh hemorrhage; thus causing much delay in drawing attention. Early detection and proper management are essential to reduce the morbidity and mortality. Various diagnostic tools are developed in the recent past, improving the detection and assessment of these lesions. Objectives: To study the profile of various non-neoplastic colorectal lesions and to know the relative frequency of various diseases, and to know the age and sex incidence of the non-neoplastic colorectal lesions. Materials and methods: This study was carried out in the Department of Pathology, NRI Medical College, Chinakakani, Guntur district. The present study comprised a total of 507 cases of colorectal Chityala Jyothi, T. Divyagna, V. Vijaya Sreedhar, M. Narsing Rao, M.N.P. Charan Paul, Kandukuri Mahesh Kumar. Profile of non-neoplastic colorectal lesions - A five year study. IAIM, 2016; 3(7): 171-180. Page 172 lesions which were received in the department of pathology as colonoscopic biopsies and resected specimens. Out of 507 cases, 187 cases were neoplastic and 320 cases belonged to the non-neoplastic group. The present study was done on the non-neoplastic colorectal lesions over a study period of 5 years, i.e. from June 2008 to May 2013. Results: The present study comprised a total of 507 cases of colorectal lesions over a study period of 5 years, i.e. from June 2008 to May 2013; which included 405 (79.88%) cases of colonoscopic biopsies and 102 (20.12%) cases of resected specimens. Out of the total 507 colorectal lesions, there were 320 (63.12%) cases of non-neoplastic lesions and 187 (36.88%) cases of neoplastic lesions. Out of 320 cases of Non-neoplastic lesions, 211 (65.94%) cases were Males and 109 (34.06%) cases were females; the predominant lesion was chronic non-specific colitis constituting 187 (58.44%) of cases and next to it is the Inflammatory bowel disease which included ulcerative colitis constituting 40 (12.50%) of cases and 10 (3.12%) cases of Crohn’s disease. Conclusion: Colorectal lesions are one of the common causes of morbidity. In routine clinical practice, histology is often considered as the gold standard when compared with other tests. Biopsy provides an excellent opportunity for the clinician and histopathologist to correlate, colonoscopic findings and pathological features