ABSTRACT
ABSTRACT Introduction: Colorectal carcinoma is commonest cancer of gastrointestinal tract. It is represent third cancer in man worldwide beyond lung and prostate cancers. It is fourth cancer in woman beyond breast, lung and uterus cancers. Deaths from colorectal cancer are more in compare with other GIT cancers. Objective: The aim is prove epidemiological and clinical data of colorectal cancer. Method: Our study conducted in Misan Province, Iraq. The data collected from 2013 to 2016. Seventy one patients that found have colorectal cancer. Gender, age, residency, site of cancer, family history, past history, year of onset, smoking history, alcohol intake, presentation, staging and histopathology pattern are get. Results: Prevalence of colon and rectum carcinoma is 3.75%. The most age group affected was 51-60 years as 30.99%. The gender and residency of patients have no effect on cancer percent. Obesity, Family history, cigarette smoking and alcohol consumption risk factors. In 42.25% of patients had family history of cancer. Conclusion: Most common site of colorectal carcinoma left colon, which present in 61.97%. There is increase in new cases detection of colorectal carcinoma from 2013 to 2016. Advanced stages cancer were most common stages description as IIIA, IIIB, IIIC and IV in 12.67%, 16.90%, 19.72% and 15.49%. The common histopathological pattern is differentiated adenocarcinoma as 53.52%.
RESUMO Introdução: O carcinoma colorretal é o câncer mais comum do trato gastrointestinal. É o terceiro tipo de câncer mais observado no sexo masculino mundialmente, atrás dos cânceres de pulmão e próstata. É o quarto câncer mais observado no sexo feminino, atrás dos cânceres de mama, pulmão e útero. As mortes por câncer colorretal são mais comuns comparadas a outros cânceres do TGI. Objetivo: O objetivo do estudo é comprovar dados epidemiológicos e clínicos do câncer colorretal. Métodos: Nosso estudo foi conduzido na província de Misan, no Iraque. Os dados foram coletados de 2013 a 2016. Setenta e um pacientes apresentaram câncer colorretal. Sexo, idade, local de residência, local do câncer, história familiar, história pregressa, ano de início, história de tabagismo, etilismo, apresentação, estadiamento e padrão histopatológico foram obtidos. Resultados: A prevalência de carcinoma de cólon e reto é de 3,75%. A faixa etária mais afetada foi de 51 a 60 anos, com 30,99%. O gênero e o local de residência dos pacientes não afetam a porcentagem de ocorrência do câncer. Obesidade, antecedentes familiares, tabagismo e consumo de álcool são fatores de risco. 42,25% dos pacientes tinha história familiar de câncer. Conclusão: O local mais comum de carcinoma colorretal é o cólon esquerdo, com 61,97%. Houve aumento na detecção de novos casos de carcinoma colorretal de 2013 a 2016. Os estágios avançados de câncer mais comuns foram IIIA, IIIB, IIIC e IV em 12,67%, 16,90%, 19,72% e 15,49% dos casos. O padrão histopatológico comum é o adenocarcinoma diferenciado, em 53,52% dos casos.
Subject(s)
Humans , Colorectal Neoplasms/epidemiology , Colonic Diseases , Risk Factors , IraqABSTRACT
In order to evaluate the immunological status against MUMPS, and hence the necessity for vaccination in Egypt, we measured the specific IgG antitibodies to mumps by ELISA in 200 subjects chosen non-randomly on purpose. Their ages ranged between 0-18 years, equally distributed between both sexes. Immunity was considered when the difference in absorbance value was > 0.2. The overall percentage of anti-mumps seroimmunity was found to be 71.5% in our subjects who were not vaccinated against mumps. No significant differeince was elicited between both sexes. All neonates [100%] in this study were immune. The age group 4 weeks -1 year had seroimimunity of 90% while the age group 1- 2 years showed the lowest seroimimunity being 23%. Then, seroimmunity increased vith the advance of age being 55% in the age group 2- G 6 years, 77.5% in the age. group 6 - 12 years and 90% in the 12 - 18 year old. The change of immunity with age was proved statistically to be highly significant. The mean IgG absorbance value [antibody concentration] in immune subjects was higher in the neonates [1.2 +/- 0.1] and adolescents [0.98 +/- 0.3] than in infants aging 1- 2 years [0.431 +/- 0.132] meaning that the latter age group had lower seroimmunity levels. The force of infection [power of virus transmission] was high below the age of 6 years being 0.280 between 1and 2 years of age and 0.240 in the age group 2 - 6 years. It was low in those aged 6 - 12 [0.176] and 12 - 18 years [0.118]. The mean age of maximum infection was 4.83 years. Mumps vaccination in Egypt is not mandatory in the presence of high seroimmnnity levels in adolescents. Nevertheless two dose schedule of mumps vaccine at 15 months and 12 years is expected to protect most persons from infection