Antimicrobial activity of candida albicans aspartyl proteinase

Candida species are present as normal body flora on the skin, buccal cavity, vagina and intestinal tract of many individuals. Low molecular weight protein produced by many intestinal microflora, inhibits the growth of Candida species, while broad-spectrum antibiotics kill most of these microflora, in turn Candida becomes activated and overgrow. to study the effect of Candida proteinase on some Gram-negative and Gram -positive bacteria. Pour plate method used to incorporate the tested bacteria in nutrient agar medium. Wells were punched with sterile cork porer. 40 of different concentrations of the enzyme was placed in each well. Zones of inhibition were measured after 24 hrs of incubation at 37°C. Concentrations of 40:1 and 20:20 were inhibitory for Klebsiella, E. coli and Enterobacter: While dilutions of iess than 50% of the enzyme were not effective against these bacteria, with the exception to lactobacilli

High titre of anti-salmonella antibodies and its clinical significance

Six workers in a working camp in Baghdad area, presented symptoms of typhoid fever. Different species of Salmonella were isolated from their blood culture. As a result, all the [308] workers on the camp were subjected to full clinical and Lab. investigations. Stool culture was positive for nine individuals [carriers]. Blood and urine cultures were negative. Hundred fifty five of the workers sera showed positive agglutination test with high titre up to 512 without any symptoms of the disease. Agglutinin [anti - o, anti - H] remained in sera of these workers for more than six months after the onset of lab. Investigations