ABSTRACT
ABSTRACT This is the first report on circulating canine rotavirus in Mexico. Fifty samples from dogs with gastroenteritis were analyzed used polymerase chain reaction and reverse transcription polymerase chain reaction in order to identify parvovirus and rotavirus, respectively; 7% of dogs were infected with rotavirus exclusively, while 14% were co-infected with both rotavirus and parvovirus; clinical signs in co-infected dogs were more severe.
Subject(s)
Animals , Male , Female , Dogs , Coinfection/veterinary , Dog Diseases/virology , Gastroenteritis/veterinary , Parvoviridae Infections/veterinary , Parvovirus/isolation & purification , Rotavirus Infections/veterinary , Rotavirus/isolation & purification , Coinfection/virology , Feces/virology , Gastroenteritis/virology , Mexico , Parvoviridae Infections/virology , Parvovirus/genetics , Parvovirus/physiology , Rotavirus Infections/virology , Rotavirus/genetics , Rotavirus/physiologyABSTRACT
The canine transmissible venereal tumor (CTVT) is found mainly in dogs' sexual organs. Currently, it is widely accepted that all samples of CTVT show similar histopathological characteristics and share common genetic alterations. Despite the common genetic origin of CTVT, mutations in the P53 gene have been reported. In this study, we proposed that tumor samples can be genetically grouped using this gene. The presence of different subgroups of CTVT was determined in Mexican dogs using the TP53 gene sequence in CTVT samples. Four new polymorphisms were found and therefore, the CTVT samples were classified in five subgroups.