ABSTRACT
Aim To study topographic findings in patients with established vernal keratoconjunctivitis (VKC). Materials and methods In a hospital based cross sectional study, 112 eyes of age group 11-22 years with established case of VKC were selected for topography. Result In 112 eyes with VKC; 69.64% (78 eyes) had significant history of eye rubbing. 14.28% (16 eyes) had Kmax values >=47.2D , 85.71%(96 eyes) had Kmax values <47.2D. 19.64%(22 eyes) had I-S Difference >=1.2D ; 80.36%(90 eyes) had I-S Difference <1.2D. Topographical patterns observed included 49.11%(55eyes) with round pattern, 20.54%(23 eyes) with oval shaped, 9.82%(11 eyes) with symmetric bowtie, 6.25%(7 eyes) with asymmetric bow tie with skewing of radial axis, 5.36%(6 eyes) with inferior steepening, 6.25%(7 eyes) with irregular pattern, 0.89%(1 eye) with crab claw pattern. ConclusionHigh occurrence of keratoconus-like topographic pattern seen in patients of VKC. Topographic analysis should be performed in all cases of VKC.
ABSTRACT
Purpose: To study the different modalities in the management of Ocular Surface SquamousNeoplasia(OSSN).Method: A prospective study of 30 cases of OSSN was undertaken. Based on patient factors andtumour size and characteristics , 20 patients underwent surgical excision with cryotherapy and 10patients were managed conservatively with topical interferon therapy. Patients were followed up for aperiod of nine months.Results: OSSN is more common in males (80%) with mean age of 55 years (range 30-76 years).Histopathology report of excision biopsy showed 6 benign dysplasia, 8 carcinoma in situ and 6invasive squamous carcinoma. Postoperative topical interferon reduced the risk of recurrence.Of the patients who underwent interferon therapy, complete resolution was seen in 6 cases.Conclusion : Management of OSSN requires adequate excision and regular follow up to monitor anyrecurrence. Although surgical excision is still the gold standard for OSSN treatment, topicalinterferon has revolutionised the management of OSSN. Pre and Post operative adjunctive therapyshould be considered to prevent recurrence.