ABSTRACT
In a country like India, oral metronidazole is the commonly prescribed drug of choice for entities such as amebiasis and visceral abscesses. Oral such cases, it is usually well tolerated and safe but can cause serious neurological adverse events. Peripheral neuropathy commonly encounters in practice but central nervous system toxicity is also well documented as it crosses the blood–brain barrier easily. Neurological toxicity of metronidazole may be due to prolonged administration, high doses, or high cumulative doses. Magnetic resonance imaging (MRI) of brain is the modality of choice to evaluate brain involvement. In the brain, the splenium of the corpus callosum, dentate nucleus of the cerebellum, and posterior pons involvement are commonly seen and diagnostic. Here, we have an interesting case report of a patient who was on oral metronidazole treatment for his large liver abscess, presenting with a complaint of neurological symptoms of unsteady gait, vertigo, dysdiadochokinesia, and difficulty in speech. Moreover, thus suspected as metronidazole drug toxicity and further investigated for the same, and MRI typically shows cerebellar and posterior corpus callosal involvement
ABSTRACT
The suprarenal arteries are arising from three sources: superior suprarenal artery, middle suprarenal artery, and inferior suprarenal artery. Variations in the arterial supply of the suprarenal glands in respect to origin and number are quite common and very frequently reported. The most common variation noted is in the inferior suprarenal artery followed by the middle suprarenal artery and the least common variations were observed in the superior suprarenal artery. Arteriogram of the inferior suprarenal artery is crucial in suprarenal tumour diagnosis but variation in the branching pattern and multiplicity of these arteries can cause hindrance in arteriography. The absence of middle suprarenal artery was seen to be associated with increased number of the inferior suprarenal artery. Variation in the multiplicity of arteries was observed more frequently in the inferior suprarenal artery and middle suprarenal artery which was more on the right side in most of the studies. Also, the variation in suprarenal arteries was often correlated to variations in inferior phrenic and gonadal arteries. The variations were observed to be more common on the left side therefore right adrenalectomy should be preferred over the left one. The loop formed by the inferior suprarenal artery around the right renal vein can cause venous obstruction. These variations of suprarenal vasculature are explained on the developmental basis, and prior knowledge of such variants is crucial for nephrologists to ensure minimum blood loss while performing laparoscopic adrenalectomy especially for large adrenal tumours and pheochromocytoma where the duration of surgery exceeds the usual.
ABSTRACT
Raymond de Vieussens was an exemplary anatomist who made seminal contributions in the field of cardiology. During initial part of his academic career, he adopted human dissection based experiments as medium of his research. This was in accordance with prevailing trend among anatomists during 17th century. He discovered the presence of tiny venous tributaries communicating between cardiac veins and chambers of heart (ducti carnosi/venae cordis minimae). He reported the existence of a collateral circulatory pathway between right and left coronary arterial systems (Vieussens arterial ring). He was the first to note the valve at the junction of great cardiac vein and coronary sinus (valve of Vieussens) and the prominent oval margin of the fossa ovalis (Vieussens Annulus). All his findings were associated with considerable clinical significance as evidenced in literature that followed. Vieussens accurately demonstrated the three-layered orientation of myocardium and gave a precise description of coronary arteries and their branches. At the onset of 18th century, buoyed by royal patronage from King Louis XIV of France, the second half of Vieussens illustrious career was defined by pathologic anatomy (autopsy based) and anatomo clinical correlations. This was a new trend initiated by Vieussens in anatomical research and was later adopted as a signature method by anatomists of 18th century. As a true connoisseur of cardiologic anatomy, Vieussens accurately charted the anatomo clinical correlations of cardiac tamponade, mitral stenosis and aortic regurgitation. His contributions were pivotal elements in metamorphosis of cardiology as a robust discipline of medicine in modern times.
ABSTRACT
Background: Self-medication is becoming a most prevalent practice among educated people across the world. In today’s era, internet and media is one of the most important sources for promoting self-medication practice. Medical students are highly influenced with this practice as their future medical preference and the fact that medical students find themselves having more knowledge about drugs this may lead to irrational usage of drugs. Aim and Objectives of the study were conducted to know the 1. Self-medication practices among medical students 2. Common, indications and reasons for self-medication practice. 3.Attitude of medical students towards self-medication practice.Methods: A cross-sectional, questionnaire-based study was conducted among undergraduate medical students of GMERS Medical College Valsad. The study was carried out in the months of October to December 2017. Medical students of first and final year MBBS participated voluntarily in this study after being briefed in detail about the goals & method of the study.Results: In this study, 91.50% of medical students were practiced self-medication. The common indication for self-medication was fever (76.50%) and cough (75.96%). Acquaintances (67.76%) are main source of information for self-medication. Common reasons they know the medicine (78.14%) and previous exposure (64.48%). 12.5% student perceived self-medication is harmless and 21.0% of medical students advise other to take self-medication.Conclusions: It was concluded that more than half of strength of students practice self-medication for various illnesses; the reason might be the awareness of drugs due to easy accessibility of information through books, internet as well as availability of medicine without prescription from pharmacist. So, essential measure should be taken to reduce the practice of self-medication among students to avoid development of drug dependence, resistance and drug interactions.
ABSTRACT
Background: The advents of new technologies are providing a variety of effective learning environment. However, many adult students still prefer traditional, academic settings and do not want to take online or hybrid classes.Methods: Present study included cross sectional descriptive survey design which was carried out on 394 undergraduate nursing students. Convenient sampling technique was chosen for selection of samples. A five-point Likert self-structured scale was used for data collection. Descriptive and inferential statistics were used to analyze the data in SPSS.Results: Study findings showed that there were 209 (53%) female participants. Significant difference (p=0.05) was found among participants’ gender and year of study, area of residence, father education, family income and whether they had ever attended online classes. Lack of control over the group was top perceived barrier with highest score (261 marks). Majority of participants (61%) perceived barriers encountered during online classes. Mann Whitney U test showed the significant differences of participants’ perceived barriers among male and female participants by their age, year of study, fathers’ education and family income (p<0.05).Conclusions: As more students are growing up familiar with internet-based learning, many students were still opposing to go with online classes. Barriers explored in the study can limit the acceptance of online classes among undergraduate nursing students. Higher authorities must find the ways for making online education user friendly.
ABSTRACT
Background: According to William Osler, a great feature which distinguishes man from animals is the desire to take medicine. Self-medication is an age old practice. According to World Health Organization guidelines “self-medication is defined as use of medicinal products by the individuals to treat self-recognized disorders or symptoms, or the intermittent or continuous use of a medication prescribed by a physician for chronic or recurring diseases or symptoms.Methods: It was a cross sectional study, which was conducted among residents of urban and rural areas of Etawah district, Uttar Pradesh by using 40×5 cluster sampling. The data was collected by using pre designed, semi-structured questionnaire. Proforma included socio- demographic profile, practice of self- medication and pattern of self-medication.Results: Most of the participants who indulged in self-medication in urban areas 69.5% and rural areas 65% belong to the age group 20-39 years. Majority of the participants (51.0%) in urban areas belonged to the nuclear family while most of the participants (50%) belonged to joint family followed by nuclear family (40%) in rural areas. most common reason for self-medication in urban area was the availability of old prescription which is present in 30.0% (60) of subjects but in rural area most common reason for self-medication was high fee of doctor which was 29.0% (58).Conclusions: Most common age group indulged in self-medication was 20-39 years. Most common reason for self-medication was availability of old prescription at home while in rural area, high fees of doctor was the common reason for self-medicatio
ABSTRACT
Introduction: The prevalence of leukemia is known to varythroughout the India. An attempt was made to find out patternof leukemia and its distribution throughout the Ajmer region.Materials and Methods: Samples of 45,391 cases werecollected in Haematology section, Department of Pathology,Jawahar Lal Nehru Medical College, Ajmer during last 2 yearsand 6 months from January 2014 to June 2016. Clinicallysuspected patients were sent for Complete Blood Count,Peripheral Blood Film and bone marrow examination and otherroutine investigations.Results: Most prevalent leukemia was Chronic MyeloidLeukemia 47 cases (35%) and least prevalent is ChronicLymphocytic Leukemia 13 cases (9.7%). Acute leukemia weremore diagnosed in young adult, while chronic leukemia weremore in middle and old age group. Leukemia was found morein male patient (male:female ratio 1.19:1).Conclusion: The commonest leukemia was found to beChronic Myloid Leukemia. Leukemia was more prevalent inmales
ABSTRACT
Neurocysticercosis (NCC) is the most common parasitic disease of the nervous system with varied clinical and imaging spectrum. This study was conducted to describe the clinical , CTfinding and response to therapy of NCC. Materials: Hundred (100) patients of NCC presenting in department of medicine, PMCH, Patna were evaluated on preset proforma containing detailed demographic data, dietary habits, clinical features and neuroimaging findings and its therapeutic response. Patients were treated with 28 days course of albendazole and repeat CTscan was done in 2 months after treatment. Results: Out of 100 patients of NCC, 56 (56%) were male with most common age group being 21-30 years (36%). Only Seizure is the most common presentation followed by Seizure with featuers of increased intracranial pressure (70 and 14% respectively). Multiple ring enhancing lesions either alone or in combination were seen on computerised tomography scans in 56 (56%) cases and parietal lobe involvement is the commonest site. Complete resolution of CTscan lesions in 72 (72%) and partial resolution occurred in rest of patients. Conclusions: Neurocysticercosis is common public health problem and one of the common cause of seizure. It has varied imaging finding being ring enhancement is most common. Albendazole is highly effective therapy and should be started at earliest to prevent morbidity and mortality
ABSTRACT
PURPOSE@#In medical colleges, resident training programs must provide adequate surgical experiences, making them qualified at the end of residency program. It is generally believed that it would take more time for a surgical resident to perform surgical procedures than a board-certified surgeon. There is no current benchmark with regards to operative time and surgical cases involving orthopedic surgery residents. In this study, we focused on two key aspects of surgical training variables, namely, surgical duration & C-arm shoots when the procedure is done by a faculty surgeon in comparison to done by an orthopedic resident under supervision of faculty surgeon.@*METHODS@#It is an observational prospective study, we observed patients undergoing 1 of 5 common orthopedic trauma operations in a community teaching hospital. We recorded two variables, 'skin to skin' surgical duration & number of image intensifier television/C-arm shoots of faculty surgeons and orthopedic resident (postgraduate-3yr) under supervision of faculty surgeon. We calculated mean difference of two variables with or without resident & determined statistical significance, we also compared functional outcome at final follow-up.@*RESULTS@#The total number of procedure observed was 402. On observing summarized results of all surgical procedures, faculty surgeons took on an average 33 min lesser (p 0.05) in functional outcome of cases performed by faulty surgeon and resident.@*CONCLUSION@#Little data has been previously published regarding the impact of teaching orthopedic resident in operating room. We demonstrate that resident participation increases the procedure time for commonly performed orthopedic procedures and also the number of C-arm shoots, hence there is a need for technical training facilities outside the operating room such as in cadaveric labs, saw bone labs & virtual surgery simulation. Also the preoperative plan should be thoroughly discussed by faculty surgeon with residents.
ABSTRACT
Introduction: About 1.4 million people around the world become seriously ill from Health Care Associated Infections at any given time The risk of infection in developing countries is 2 to 20 times higher than in developed countries and its incidence in India ranges from 5-30%. Aims and objectives:To study knowledge and practices regarding hand hygiene among Health Care Providers and to study the factors affecting the hand hygiene adherence Method:Cross sectional study conducted in tertiary care of hospital of Valsad. Prior oral informed consent was taken from the participants before the start of the study. An anonymous questionnaire formed as per WHO guidelines on hand hygiene was used as data collection tool. Results 64% medical and 72% paramedical staff has taken training in hand hygiene in last three years. 19.37% medical and 26.02% paramedical staff reported less time and more work load as barriers in implementing routine hand hygiene practices respectively. 20.93% medical and 6.97% paramedical staff reported training as an important factor for improved hand hygiene practices in the hospital. 66% staff of both groups correctly knows about required time needed for hand washing practice as per WHO guidelines whereas 26% medical and 44% paramedical staff doesn't have correct knowledge of hand hygiene practices when hands are visibly soiled Conclusion Lack of correct knowledge regarding hand hygiene practices among health care providers.
ABSTRACT
<p><b>PURPOSE</b>Wrist has a complex anatomy and undergoes complex injuries. Scaphoid fracture is one of such injuries. It is the most common fracture in carpal bone. Most of the scaphoid fractures are missed on initial X-rays. Magnetic resonance imaging (MRI) is considered as a gold standard for diagnosing scaphoid fractures. Ultrasonography (USG) is emerging as a good alternative to make an early diagnosis of scaphoid fractures. Our aim is to throw light upon the role of USG in detection of scaphoid fractures.</p><p><b>METHODS</b>The study was centered upon 114 patients in the age range 10-65 years, with traumatic wrist injury and were clinically suspected to have scaphoid fractures. Patient with non-traumatic history, bilateral wrist injury and late presentation were excluded. X-rays, USG using high frequency probe and MRI were done for all patients. MRI was considered to be the gold standard test. Patients were followed up at 6 weeks.</p><p><b>RESULTS</b>Of the 114 patients, X-ray could diagnose scaphoid fractures in 48 patients, 30 of which were confirmed by MRI. USG results were positive in 74 patients, of which MRI was positive in 67 patients. The accuracy of scaphoid fracture detection with USG was 98.04% in comparison to X-ray (20.58%), which was statistically significant.</p><p><b>CONCLUSION</b>USG provides a more accurate and reliable method of making an early diagnosis of scaphoid fracture than X-rays. It is non-invasive, non-expensive and allows better visualisation of cortical disruption.</p>
Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Young Adult , Fractures, Bone , Diagnostic Imaging , Magnetic Resonance Imaging , Prospective Studies , Scaphoid Bone , Wounds and Injuries , Ultrasonography , MethodsABSTRACT
Introduction: Computed tomography (CT) is the preferred diagnostic toolkit for head and brain imaging of head injury. A recent development is the invention of a portable CT scanner that can be beneficial from a clinical point of view. Aim: To compare the quality of CT brain images produced by a fixed CT scanner and a portable CT scanner (CereTom). Methods: This work was a single-centre retrospective study of CT brain images from 112 neurosurgical patients. Hounsfield units (HUs) of the images from CereTom were measured for air, water and bone. Three assessors independently evaluated the images from the fixed CT scanner and CereTom. Streak artefacts, visualisation of lesions and grey–white matter differentiation were evaluated at three different levels (centrum semiovale, basal ganglia and middle cerebellar peduncles). Each evaluation was scored 1 (poor), 2 (average) or 3 (good) and summed up to form an ordinal reading of 3 to 9. Results: HUs for air, water and bone from CereTom were within the recommended value by the American College of Radiology (ACR). Streak artefact evaluation scores for the fixed CT scanner was 8.54 versus 7.46 (Z = -5.67) for CereTom at the centrum semiovale, 8.38 (SD = 1.12) versus 7.32 (SD = 1.63) at the basal ganglia and 8.21 (SD = 1.30) versus 6.97 (SD = 2.77) at the middle cerebellar peduncles. Grey–white matter differentiation showed scores of 8.27 (SD = 1.04) versus 7.21 (SD = 1.41) at the centrum semiovale, 8.26 (SD = 1.07) versus 7.00 (SD = 1.47) at the basal ganglia and 8.38 (SD = 1.11) versus 6.74 (SD = 1.55) at the middle cerebellar peduncles. Visualisation of lesions showed scores of 8.86 versus 8.21 (Z = -4.24) at the centrum semiovale, 8.93 versus 8.18 (Z = -5.32) at the basal ganglia and 8.79 versus 8.06 (Z = -4.93) at the middle cerebellar peduncles. All results were significant with P-value < 0.01. Conclusions: Results of the study showed a significant difference in image quality produced by the fixed CT scanner and CereTom, with the latter being more inferior than the former. However, HUs of the images produced by CereTom do fulfil the recommendation of the ACR.
ABSTRACT
Young individuals with fatigue fractures are often a result of the repetitive athletic activity. Military recruits, distance runners, and dancers are commonly affected and are at an increased risk of developing stress fractures in the hip. We report a case of fatigue fracture of the femoral neck in a 20-year-old software professional as the first presentation of celiac disease. The skeletal manifestation of celiac disease is rare (0.6%). The case was managed with in situ fixation with cannulated screws and gluten free diet. The patient was pain free with no evidence of osteonecrosis, nonunion, or any other complication at 1-year follow-up.
ABSTRACT
Extended-spectrum β-lactamases (ESBLs) are rapidly evolving group of β-lactamase enzymes produced by the Gram negative bacteria. In this study, we determined the antimicrobial sensitivity pattern of Escherichia coli isolates and prevalence of TEM, SHV and CTX-M genes in ESBL positive E. coli isolated from the patients admitted to a tertiary care hospital in North-East India. A total of 85 multidrug-resistant isolates of E. coli obtained from clinical samples; urine (n=80), sputum (n=3), body fluid (n=1), vaginal discharge (n=1) were screened for resistance to third generation cephalosporins. ESBL production in resistant isolates was determined by double disk synergy test (DDST) and phenotypic confirmatory test (PCT). ESBL positive isolates were subjected to PCR for detection of TEM, SHV and CTX-M genes. Imipenem was found to be most effective against E. coli (susceptible isolates 96.47%) while ciprofloxacin was the least effective antibiotic (resistant isolates 60%). Among 33 ESBL positive isolates confirmed via PCT, preponderance in female population (60.6%) was noted. The most prevalent gene was blaSHV (63.04%) followed by blaTEM and blaCTX-M (60.86 and 54.34%, respectively) in ESBL positive E. coli. Most of the extensively used antibiotics, appear to be ineffective against the ever-mutating bacteria. This resistance urges cautious antimicrobial management on priority. Further, it helps in effectively designing the chemotherapeutic regimen for patients of a particular geographic area.
ABSTRACT
BACKGROUND: For surgical treatment of lumbar and lumbosacral tuberculosis, the anterior approach has been the most popular approach because it allows direct access to the infected tissue, thereby providing good decompression. However, anterior fixation is not strong, and graft failure and loss of correction are frequent complications. The posterior approach allows circumferential decompression of neural elements along with three-column fixation attained via pedicle screws by the same approach. The purpose of this study was to evaluate the outcome (functional, neurological, and radiological) in patients with lumbar and lumbosacral tuberculosis operated through the posterior approach. METHODS: Twenty-eight patients were diagnosed with tuberculosis of the lumbar and lumbosacral region from August 2012 to August 2013. Of these, 13 patients had progressive neurological deterioration or increasing back pain despite conservative measures and underwent posterior decompression and pedicle screw fixation with posterolateral fusion. Antitubercular therapy was given till signs of radiological healing were evident (9 to 16 months). Functional outcome (visual analogue scale [VAS] score for back pain), neurological recovery (Frankel grading), and radiological improvement were evaluated preoperatively, immediately postoperatively and 3 months, 6 months, and 1 year postoperatively. RESULTS: The mean VAS score for back pain improved from 7.89 (range, 9 to 7) preoperatively to 2.2 (range, 3 to 1) at 1-year follow-up. Frankel grading was grade B in 3, grade C in 7, and grade D in 3 patients preoperatively, which improved to grade D in 7 and grade E in 6 patients at the last follow-up. Radiological healing was evident in the form of reappearance of trabeculae formation, resolution of pus, fatty marrow replacement, and bony fusion in all patients. The mean correction of segmental kyphosis was 9.85° postoperatively. The mean loss of correction at final follow-up was 3.15°. CONCLUSIONS: Posterior decompression with instrumented fusion is a safe and effective approach for management of patients with lumbar and lumbosacral tuberculosis.
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Back Pain , Cohort Studies , Decompression, Surgical/adverse effects , Lumbosacral Region/surgery , Pain Measurement , Postoperative Complications , Spinal Fusion/adverse effects , Tuberculosis, Spinal/surgeryABSTRACT
Background: The objective of this retrospective study was to compare the efficacy of slow freezing and Vitrification for the cryopreservation of supernumerary cleavage stage embryos on day 3 after IVF and its impact on clinical outcome. Methods: 485 supernumerary embryos of IVF cycles (from Oct 2011 to Dec 2012) were cryopreserved by slow freezing method while 502 embryos (from Jan 2013 to April 2014) by Vitrification method. 362/485 and 230/502 embryos were thawed for FET cycles (65 patients in each group).After warming the survival rate, post warmed embryo morphology, clinical pregnancy and implantation rates were evaluated and compared between the two groups. Results: There were 65 frozen thawed cycles in each group. The percentage of excellent and good morphology embryos before cryopreservation were same in both the groups, but after thawing the results were significantly in favour of Vitrification as compared to Slow freezing. In Vitrification group versus Slow freezing group, the different outcomes were survival rate (96.95% vs. 69.06%, p-0.000), post warmed excellent morphology embryos (94.17% vs. 60.8%, p-0.000) clinical pregnancy rate (41.53% vs. 21.53%, p-0.043) and the implantation rate (14.41% vs. 7.01%, p-0.024). Conclusions: Vitrification is a promising alternate to the conventional slow freezing method in terms of not only excellent survival and post warmed excellent morphology embryo rate but also higher clinical pregnancy and implantation rate.
ABSTRACT
Background: A functioning gracilis muscle is considered the ideal flap to improve the functional/aesthetic outcome with minimal donor site morbidity. This graceful and slender muscle with special attributes is increasingly being used for covering soft tissue defects, repair of urogenital fistulas and restoration of anal function. Only some studies describing the quantification of this muscle are available and population attributes of the muscle have not been taken into consideration. The present study quantifies the human gracilis muscle in a North Indian population. Methods: The morphometry of gracilis was studied in 50 inferior extremities obtained from 25 phenol embalmed adult North Indian cadavers with known age and sex. The length and width of the aponeurotic origin, the length of the muscle belly, length of the distal tendon of insertion were measured. The muscle, tendon ratios were derived. Results: The mean estimates for various morphological features of gracilius muscle were standardized for North Indians. All the origins and insertions for the muscle correlated with the standard textbook descriptions. No variation was found from a standard textbook pattern in the present sample. The reconstructive procedures should take the local population profile into consideration. Conclusion: The results will aid the clinician in choosing an appropriate muscle and tendon lengths in surgeries. This definitely will lead to better functional and aesthetic outcomes in restorative procedures.
ABSTRACT
Objective: To evaluate the effect of endometrial thickness, pattern and E2 level on the day of human chorionic gonadotropin (hCG) administration on clinical outcome in patients undergoing in vitro fertilization and embryo transfer (IVF-ET). Method: A total number of 112 cycles of IVF-ET conducted at Jaipur Fertility Centre, an Infertility Unit of Mahatma Gandhi University of Medical Sciences and Technology, Jaipur were observed prospectively. Endometrial ultrasonographic characteristics and E2 levels were recorded on the day of hCG administration. Clinical pregnancy rates were analyzed with different endometrial thickness and E2 levels. Results: Overall 37.5% patients conceived and in these women endometrial thickness was between 6-14 mm. Only 2.38% patients conceived with an ET of <6 mm. Maximum patients (52.33%) who conceived were with an ET of 8-10 mm. It was observed that endometrial thickness pattern did not have significant effect on clinical pregnancy rate in these cases. Clinical pregnancy rate was significantly higher in patients with serum E2 levels between 1,000-2,500 pg/mL as compared to other two groups. Conclusion: When thin endometrium ≤6 mm with no triple-line coexist and serum E2 level is >2,500 pg/mL in IVF/ICSI-ET, candidate cryopreservation should be recommended.
ABSTRACT
Prior to the development of intracytoplasmic sperm injection (ICSI), azoospermic and severely oligospermic men had little to no chance of having a biological child. In this study, ICSI outcome in 212 transfers with ejaculated spermatozoa and 44 transfers with surgically retrieved spermatozoa were evaluated. Material and methods: The 68 singleton gestations achieved by ICSI were segregated according to underlying infertility etiology, with 54.41% having male factor and 45.59% having female factor. None of the patients had coexisting infertility factor. Results: The miscarriage rate of all ICSI singleton gestations during the first trimester was 19.12%. There were no significant differences in early pregnancy loss (EPL) rate by infertility factor. Among patients undergoing ICSI because of male factor, there were no significant differences in EPL using ejaculated or nonejaculated sperm. Regardless of etiology, women aged ≥35 years had significantly higher EPL (36.36%). Conclusion: Our preliminary results demonstrate that first trimester miscarriage rates of ICSI gestations are not affected by underlying infertility etiology but are affected by maternal age.
ABSTRACT
Background: To survive in this competitive world, one has to go through a lot of stresses & strains which, in due course of time, reflected in altered physiology of body. One such change is the cardiovascular response to cold stress. Yoga has been reported to be beneficial as a de-stressing technique. Aims & Objective: To investigate whether regular practice of Yoga which includes Suryanamaskar, Pranayama & Meditation for 3 months could reduce the cardio-vascular hyper-reactivity induced by cold stress. Materials and Methods: In the present study, 53 young healthy medical students underwent cold pressor test. 20 turned out to be hyper reactors to this test. These hyper reactors performed Yoga (Suryanamaskar, Pranayama & Meditation) for 3 months and Cold Pressor Test was again performed at the end of this period and cardiovascular hyper-reactivity (parameters are Blood pressure, Pulse rate, and Respiratory rate) before and after yoga compared. Results: Our results showed that 14 out of original 20 hyper reactors (70 %, P<0.001) were converted to hypo reactors. Conclusion: Regular practice of Yoga reduces cardiovascular hyper-reactivity to cold pressor test. If we can spread its benefits and importance to the society we can reduce the risks of many diseases especially those related to stress.