ABSTRACT
Objectives: The object of this study is to evaluate clinical, biochemical and ultrasonographyic findings in early diagnosis of Dengue Hemorrhagic Fever [DHF]
Design: A case series
Place Study: The study was carried out in Medical Department of CMH and Mayo Hospital, Lahore
Methodology: 351 patients suspected of DHF were enrolled in two different hospitals of Lahore during outbreak of the disease. The diagnosis was confirmed by serology
Results: The most common symptom in 100% patients was fever followed by musculoskeletal pain. Liver biomarkers were elevated in 237 [77.9%] patients throughout the coarse of illness, reaching peak on 3[rd] day and declining after 7[th] day of illness. The sonographic features included hepatomegaly in 234 [77.2%] patients, pleural effusion in 226 [74.6%], thickening of gallbladder wall in 221 [72.9%] and ascites in 209 [69%]
Conclusion: Liver biomarkers and abdominal ultrasonography can be used as first line of imaging modality in patients, suspected of DHF prior to serological confirmation in dengue epidemic area
ABSTRACT
Objective: to assess the diameter of the pd'riaI vein for predicting esophageal varices [EV] in a group of cirrhotic patients
Study Design: cross sectional study
Place and Duration of Study: study was conducted in Medical Department of Service Hospital from December 2008 to June 2009
Material and Methods: one hundred and eighty cirrhotic patients with age range 20-60 years were admitted in Medical Department of Services, Lahore, to analyst assesses and document, the diameter of portal vein as non-invasive parameters taken by ultrasonography to predict esophageal varies in cirrhotic patients. It was confirmed by endoscopy taken as gold standard
Results: portal vein diameter [PVD] has mean sensitivity of 98:5%, specificity of 90.2%, diagnostic accuracy of 96.6%, positive predictive value of 97.1 % and negative pred1cllve value of 94.8% m detecting EV. Positive percentage of EV via endoscopy was 78.3%. On the other hand positive percentages of EV via PVD were 76.1 %
Conclusion: it is therefore concluded that patients of chronic liver disease of any etiology can be screened for esophageal varices using PVD as a non-invasive parameters