ABSTRACT
Background: Analgesia is meant to reduce the pain produced by surgery. To fulfil this requirement various drugs such as alcohol, opium, hashish and balladona have been used in the past by the Egyptians and Chinese for the control of pain during surgery when the anesthesia was not known. Glucose is a carbohydrate required for energy. During the process of metabolism of glucose the source storage come into play. Nervous influence, enzymatic action and hormonal involvement also have a significant role. Aim: The aim of the study was the study of blood glucose level changes during general anesthesia in patients under surgery. Materials and methods: The present study was done in the department of Anesthesiology during the year 2015-2016, 60 patients with age group of 25-65 years along with different sex distribution. Results: Regarding the anaesthesia group, there were 15 patients in the age group of 25-35 years and 36-45 years each.14 patients were in age group 46-55 years, while 16 patients in the age group of 56- G.V. Krishna Reddy, M. Madan Mohan Rao, G obulesu, R Salma Mahaboob. The study of blood glucose level changes during general anesthesia in patients undergoing surgery. IAIM, 2017; 4(1): 110-115. Page 111 65 years. Out of 60 patients 33 patients (55%) were male patients while remaining 27 patients (45%) were female patients. Conclusion: Present study showed that there is very highly significant rise in blood glucose level during the ether anesthesia while in case of relaxants there is only significant rise in blood glucose level.
ABSTRACT
Background: Emergence agitation is a short lived phenomenon occurring commonly after nasal surgery. In this study we used dexmedetomidine infusion in that intraoperative period to decrease the incidence of emergence agitation in adult male and female patients posted for nasal surgery. Aim: Study the effect of dexmedetomidine on emergence agitation after nasal surgeries. Materials and methods: 110 adult patients (ASA I-II, 22-65 years posted for nasal surgery were randomly divided into two groups. Group D received infusion of dexmedetomidine 0.4mcg/kf/hr during the intraoperative period, and Group C received normal saline infusion as placebo. All patients were induced with fentanyl (1 mcg/kg) and propofol (1.5 mcg/kg) and maintained with isoflurane. Incidence of agitation, hemodynamics, pain scores, time to verbal commands and extubation were evaluated. Results: Incidence of emergence agitation was lower in Group D (26%) than Group C (50%). Group I showed more stable hemodynamics than Group II. Time to verbal response and extubation was more for Group D than Group C (p < 0.05) though it was not clinically significant. Conclusion: The use of dexmedetomidine as intraoperative infusion resulted in smooth emergence with more stable hemodynamics.