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1.
Arch. med. res ; 29(2): 125-32, abr.-jun. 1998. tab, ilus
Article in English | LILACS | ID: lil-232626

ABSTRACT

Background. The aim of the study was to investigate how neonatal undernutrition interacts with mother-infant relationship to interfere with the expression of the urogenital response in the newborn. Methods. The hyperextensive reflex components associated to the urogenital response (HUR) were measured between postnatal days 1-21, in control and neonatally undernourished rats with or without fullness of the bladder. Results. In Experiment 1, both male and female underfed rats with different degress of bladder fullness exhibited an increment in HUR latency and vertical hindlimb displacement, reduced transversal separation and prolonged performance of hindlimb relaxation. Experiment 2 was performed in rats after urine elicitation provoked only reduced hindlimb transversal separation in males, and prolonged latency to HUR in females. Discussion. These findings may be related to the vulneability to neonatal undernutrition of the maturational processes which take place in the spinal cord, the condition of the bladder, and hinleg muscle maturation during this period of life. Conclusions. Data suggest that neonatal undernutrition may play a role in mother-infant interaction by interfering with HUR responses to maternal anogenital licking of pups


Subject(s)
Animals , Male , Female , Rats , Animals, Newborn , Extremities , Hindlimb , Range of Motion, Articular , Rats, Wistar , Reflex/physiology , Urogenital System/physiology
2.
Bol. estud. méd. biol ; 41(1/4): 3-7, ene.-dic. 1993. tab
Article in English | LILACS | ID: lil-135043

ABSTRACT

En ratas Wistar normales y tratadas neonatalmente con tiroxina, se obtuvieron cortes seriados del tálamo, teñidos con el método de Golgi-Cox en las edades de 12,20 y 30 días. En la zona de núcleo reticular talámico (TRN), se contó el número de neuronas visibles, el área y la máxima extensión transversal del TRN en un total de 120 secciones. Los hallazgos indicaron que con relación al numero de neuronas en los animales tratados con T4, ocurrió un incremento signifiativo inicial de ellas a los 12 días de edad, seguido de un decremento igualmente significativo a los 20 y 30 días postnatales. Con respecto al área y a la máxima extensión transversal del TRN, sólo se observó una reducción progresiva que alcanzó sus valores más bajos a los 30 días de edad, sin ocurrir el incremento inicial que se ha descrito para el tejido neuronal. Los hallazgos sugieren que el tratamiento neonatal con T4, pudiera interferir con el desarrollo neuronal del TRN y, asimismo, a largo plazo, con las funciones modulatorias sensoriales del TRN


Subject(s)
Animals , Rats , Histology, Comparative/instrumentation , Neurons/drug effects , Thalamus , Thyroxine/pharmacology , Histology, Comparative , Neurons/cytology , Neurons/physiology , Thalamus/cytology , Thyroxine/administration & dosage , Thyroxine/physiology
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