ABSTRACT
High recurrence rate and metastasis rate after primary surgery for hepatocellular carcinoma have been restricting the long-term survival of patients. For the treatment of recurrent hepatocellular carcinoma, comprehensive treatment based on surgery is the main strategy. For patients who are unsuitable for surgery,local ablation,TACE,radiotherapy, systemic chemotherapy, targeted therapy,immunotherapy,traditional Chinese medicine and optimal supportive therapy are effective measures,which can delay disease progression and improve patient survival. According to the patient's characteristics and individual differences,the multidisciplinary treatment model should be adopted to optimize the treatment effect and reduce side effects,which will benefit the patients with better medical experience and longer overall survival rate.