ABSTRACT
Benzidine based azo dyes are proven carcinogens, mutagens and have been linked to bladder cancer of human beings and laboratory animals. The textile and dyestuff manufacturing industry are the two major sources for releasing of azo dyes. Various research groups have started work on genotoxic effect of textile dyes in occupational workers of textile dye industry. Bladder cancer is the most common form of cancer in dye industries. Most of people between age 50 and 70 group of are diagnosed with bladder cancer. Men are more likely than the women to develop bladder cancer. Bladder cancer is a disease in which abnormal cells multiply without control in the bladder. The most common type of bladder cancer begins in cells lining the inside of the bladder and is called transitional cell carcinoma. Tumor markers are substances that can be found in the body when cancer is present. They are most often found in the blood or urine. The review deals about the impacts of the industry dyes on human health.
ABSTRACT
Distribution of major groups of enteric bacteria viz., Escherichia coli, Shigella spp., Salmonella spp., Vibrio parahaemolyticus and Vibrio cholerae was studied in the sediment samples collected from different depths of 5, 15, 25 and 35 m in Parangipettai and Cuddalore coast during March, 2009 to February, 2010. Among the bacterial population in Parangipettai, V. parahaemolyticus was found to be maximum with an occurrence of 55% followed by Shigella spp. (15%), V. cholerae (12%), Salmonella spp. (12%) and E. coli (6%). In Cuddalore, as an oddity, Vibrio cholerae emerged as dominant species with an incidence of 60% of the total. V. parahaemolyticus came next in the order with an incidence of 14%, followed by E.coli (11%), Shigella spp. (8%) and Salmonella spp. (7%). Similarly, monsoon and premonsoon seasons registered higher bacterial populations in both the regions. When the depth wise results were viewed, 5 and 15 m depths showed maximum (V. parahaemolyticus 3.7x 10 CFU g-1 in Parangipettai; V. cholera - 8.6x10 CFU g-1 in Cuddalore) bacterial population compared to subsequent depths. Cluster and MDS also showed distinct spatial and seasonal variations of bacterial populations in both the regions. Biota-Environment (BIO - ENV) method revealed the combinations of temperature, salinity and TOC as the best match influencing bacterial population.
ABSTRACT
The present study was undertaken to find out the toxic effect of synthetic pyrethroid lambda cyhalothrin on the functioning of endocrine glands in freshwater catfish, Clarias batrachus.The fish were exposed to the pesticide for a period of 45 days at a sublethal concentration of 5.768 ppm. Analysis of hormone profile was carried out on the 15, 30 and 45 days of exposure to find out the alteration in hormone secretion and the response of the fish to the compound. The results obtained showed a significant decline(p<0.05) in levels of thyroid hormones and testosterone while a significant increase (p<0.05) was observed in cortisol levels during the different days of exposure of the fish to lambda cyhalothrin
ABSTRACT
Bromadiolone, a second generation anticoagulant rodenticide was tested on Mus musculus to evaluate its effects on blood, liver and kidney at varied time intervals of 6, 12, 24 and 48 hrs. Groups of six animals each were selected for experiment. Animals were administered with bromadiolone in the form of bait at 6, 12, 24 and 48 hrs time intervals. Control animals were maintained for each time interval. After each time interval the experiment and the control animals were sacrificed and the effect of bromadiolone on blood, liver and kidney were studied.