ABSTRACT
A survey of malaria in Northwest Mindoro, Occidental, Mindoro, Philippines is reported. Three species of human plasmodia were identified from 600 blood films examined. The overall prevalence of malaria was 7% (2.8% P. falciparum, 4.3% P. vivax, 0.7% P. malariae). The prevalence of malaria was highest (24%) among children 0 to 15 years of age and only 4 cases (12%) were found among persons over the age of 15. Males and females were equally infected. Study sites with the highest slide-positivity rate were located in the foothill regions which corresponded with the observed presence of two malaria vectors, Anopheles minimus flavirostris and An. maculatus. These sites appeared to be adequate for future studies of drug-resistance, although large numbers of suitable candidates would not be expected.
Subject(s)
Adolescent , Adult , Aged , Anopheles/parasitology , Arachnid Vectors/parasitology , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Malaria/epidemiology , Male , Middle Aged , Philippines , Plasmodium falciparum , Plasmodium malariae , Plasmodium vivaxABSTRACT
Foram estudados dois grupos de pacientes portadores de malaria por P. falciparum que receberam o antibiotico durante sete dias. A um desses grupos, com 24 pacientes foi administrada a dose de 300 mg/dia, dividida a cada 12 horas. A via endovenosa foi utilizada durante tres dias e, a seguir, a via oral por mais quatro dias. Ao outro grupo, de 12 pacientes, administrou-se 600 mg/dia de clindamicina seguindo identico regimen do grupo anterior.Em testes de resistencia a cloroquina, evidenciou-se positividade em cinco pacientes do primeiro grupo e tres do segundo, a nivel de R-II. Ambos os regimes provaram efetividade na cure de malaria por P. falciparum