ABSTRACT
To determine correlation of clinical indication of hysterectomies with histological findings and association with age and parity. Institution based cross sectional study. This study was conducted at the Lady Dufferin Hospital, Karachi, Pakistan from Jan. 2007 to Dec. 2009. 322. Non Probability Purposive sampling. A structured standardized Proforma was used to collect data between Jan 2007 to Dec 2009 from the pathological laboratory data on surgical hysterectomies. The data comprised of clinical, physical and histological examination. The analysis was made on correlation of clinical indication of hysterectomies with histological findings and association with age and parity. Correlation of Clinical Indications and histological findings on uterus [endometrium and myometrium], cervix and ovaries. Three hundred twenty two abdominal hysterectomies were studied. Among the study subjects the mean +/- SD age was 42.36 +/- 6.36. Only 12 [3.7%] women were unmarried. Clinically the commonest indications were Leiomyoma in 167 [519%] and DUB 120 [37.7%]. Ovarian mass was clinical indication in 4 [1.3%] cases. Histopathology revealed leiomyoma 149 [46.3%] as the commonest uterine pathology, followed by adenomyosis. Inflammation with squamous metaplasia 252 [78.2%] was the most common pathology noted in the cervix whereas 101 [46.4%], cystadenomas were noted in 6 [2.8%] and Benign teratoma in 3 [1.4%]. Hysterectomy is a major gynecological procedure therefore it should be performed after accurate clinical assessment and with proper and justified indications