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1.
Arq. bras. med. vet. zootec. (Online) ; 72(5): 1737-1741, Sept.-Oct. 2020. tab, ilus
Article in English | LILACS, VETINDEX | ID: biblio-1131558

ABSTRACT

The cutia (Dasyprocta agouti) and capybara (Hydrochoerus hydrochaeris ) are hystricomorphic rodents of the Brazilian fauna. The wild animal anatomy is essential to the clinic and surgery practices and conservation programs. This work aimed to evaluate the heart quantitative morphology of the cutia and the capybara. For this, three hearts of cutia and three of capybaras were used from the collection of the Anatomy Sector of Domestic and Wild Animals of the Faculty of Veterinary Medicine and Animal Science of the University of São Paulo. The hearts were weighted and measured with a pachymeter. The left ventricle volume was estimated through the Cavalieri method. The hearts' mean weight was 16.76g (cutias) and 104.2g (capybaras). The mean values for the axis, width and base dimensions were of the cutia 4.3cm, 3.3cm and 3.3cm and for the capybara were 7.6cm, 6.0cm and 6.1cm, respectively. The mean volume of the left ventricle of the cutia and the capybara was 5.03cm3 and 54.55cm3, respectively. The quantitative results of the hearts were compatible with the average body weight of the rodents. Thus, these numerical data can be applied to veterinary cardiology.(AU)


A cutia (Dasyprocta agouti) e a capivara (Hydrochoerus hydrochaeris) são roedores histricomorfos da fauna brasileira. A anatomia de animais silvestres é essencial para a prática clínico-cirúrgica e programas conservacionistas. Este trabalho objetivou avaliar a morfologia quantitativa do coração da cutia e da capivara. Para isso, foram utilizados três corações de cutias e três de capivaras, provenientes do acervo do Setor de Anatomia dos Animais Domésticos e Silvestres da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo. Os corações foram pesados e as mensurações foram realizadas com paquímetro. O volume do ventrículo esquerdo foi calculado pelo método de Cavalieri. O peso médio dos corações foi de 16,76g (cutias) e de 104,2g (capivaras). Os valores médios para as dimensões eixo, largura e base foram, para a cutia, de 4,3cm, 3,3cm e 3,3cm e para a capivara, de 7,6cm, 6,0cm e 6,1cm, respectivamente. O volume médio do ventrículo esquerdo da cutia e da capivara foi respectivamente de 5,03cm3 e de 54,55cm3. Os resultados quantitativos dos corações foram compatíveis com o peso corporal médio dos roedores. Assim, esses dados numéricos podem ser aplicados à cardiologia veterinária.(AU)


Subject(s)
Animals , Rodentia/anatomy & histology , Dasyproctidae/anatomy & histology , Heart/anatomy & histology , Body Weights and Measures/veterinary , Animals, Wild/anatomy & histology
2.
Arq. bras. med. vet. zootec ; 66(3): 697-704, 06/2014.
Article in English | LILACS | ID: lil-718080

ABSTRACT

The acute intoxication of Cypermethrin in Silver Catfish (Rhamdia quelen) was evaluated. Animals weighing 56.67±4.43g and measuring 18.92±1.16cm were exposed to sublethal concentrations of Cypermethrin for the species in hydrological conditions during 96 hours. A total of 52 fish divided into three groups were used and received the following concentrations of Cypermethrin: 0 (n=12); 1.5 (n=20) and 2.5 (n=20)mg/L. The intoxicated animals suffered behavioral changes such as loss of balance, swimming alteration, dyspnea, upright swimming and sudden spiral swimming movements. As soon as the 96-hour period was over, a blood collection for hematological and biochemical analyses was performed. A complete haemogram test, plasmatic protein test, albumin, alanine transaminase (ALT), aspartate aminotransferase (AST), gamma glutamyltransferase and alkaline phosphatase (ALP) were studied. The values of erythrocytes, hematocrits, haemoglobin, total number of leukocytes, thrombocyte, ALT, AST and ALP changed according to the groups. The results have shown that the environmental contamination by Cypermethrin is toxic to the species...


Avaliou-se a intoxicação aguda da cipermetrina em jundiás (Rhamdia quelen). Jundiás que pesavam 56,67±4.43g e mediam 18,92±1,16cm foram expostos a concentrações subletais de cipermetrina para a espécie em 96 horas, via hídrica, utilizando-se 52 peixes, distribuídos em três grupos, segundo a concentração de cipermetrina: 0 (n = 12); 1,5 (n = 20) e 2,5 (n = 20)mg/L. Os animais intoxicados apresentaram alterações comportamentais, como perda de equilíbrio, dispneia, natação na posição vertical e movimentos bruscos de natação em espiral. Após 96 horas de exposição, foi coletado sangue para análises de hemograma completo, proteína plasmática, albumina, alanina aminotransferase (ALT), aspartato aminotransferase (AST), fosfatase alcalina (ALP) e gamaglutamiltransferase. Os valores de eritrócitos, hematócrito, hemoglobina, número total de leucócitos, número total de plaquetas, ALT, AST e ALP diferiram entre os grupos. Os resultados demonstraram que a contaminação ambiental por cipermetrina é tóxica para a espécie...


Subject(s)
Animals , Blood Chemical Analysis/veterinary , Catfishes/metabolism , Pyrethrins/poisoning , Toxicological Symptoms , Insecticides/poisoning
3.
Arq. bras. med. vet. zootec ; 64(2): 488-490, abr. 2012. tab
Article in Portuguese | LILACS | ID: lil-622505

ABSTRACT

A total of 76 samples of Streptococcus suis isolated from meningitis cases in pigs from 2005 to 2009 were evaluated. The samples were collected from 3 to 21-week-old pigs raised in 30 farms located in Paraná state, Brazil. The samples of S. suis were obtained as part of routine procedures and were serotyped by coagglutination test using rabbit hyperimmune sera for the serotypes 1 to 9 and ½. S. suis type 2 was the most frequent, followed by serotypes 1, ½ and 3.

4.
Int. j. morphol ; 30(1): 222-229, mar. 2012. ilus
Article in Spanish | LILACS | ID: lil-638790

ABSTRACT

La Odontología forense es una rama de las Ciencias Forenses que se utiliza para establecer la identidad de una víctima o victimario mediante el estudio de las huellas de mordeduras, estimación de edad cronológica, entre otros. Dada la inexistencia de este tipo de estudios en Chile y la magnitud que alcanza el problema de mordidas de perros en Chile, se compararon los patrones de huellas de mordedura según forma del cráneo, mediante el análisis morfológico y morfométrico de semiarcadas dentarias de perro doméstico (Canis familiaris) con fines médico legal. Para ello se obtuvieron modelos dentarios en yeso e impresiones de huellas de mordedura en cera de tres razas puras: Bóxer, Dálmata y Ovejero Alemán. Las mediciones contemplaron la distancia máxima externa entre caninos superiores e inferiores y la distancia máxima externa entre incisivos superiores e inferiores. Los principales resultados muestran que sólo la distancia máxima entre caninos superiores permitiría identificar la raza en forma estadísticamente significativa (p0,05) en los modelos de yeso. En el estudio ciego y desde el punto de vista morfométrico se identificaron especialmente los Dálmata con un alto grado de sensibilidad y especificidad. Un poco menor y en forma variable se observó en Bóxer y Ovejero Alemán. El estudio morfológico permitió identificar e individualizar al 100 por ciento de los perros. Por tanto los métodos morfométricos y morfológicos son herramientas complementarias para identificar e individualizar a un posible perro agresor.


Forensic dentistry is a branch of Forensic Sciences used to establish the identity of a crime victim or perpetrator, among these studies are bite marks and dental chronological age studies. In the absence of such studies in Chile and considering the widespread problem of dog bites in Chile, bite patterns were compared according to skull shape, by morphological and morphometric analysis of dental semi arcs of domestic dog (Canis Familiaris) for medico legal purposes. Plaster dental models and impressions of bite marks were obtained of three pure breeds: Boxer, Dalmatian and German shepherd. Measures included he maximum external distance between upper and lower canine, and maximum external distance between upper and lower incisors. Main results show that only the maximum distance between upper canine would allow statistically significant race identification, (p0.05) in cast models. In a blind study and from a morphometric point of view, Dalmatians were identified with a high rate of sensitivity and specificity. A somewhat lesser and variable form was observed in Boxer and German Shepherd. The morphological study allowed identification and individualization of 100 percent of dogs. Therefore, both morphological and morphometric methods are useful and complementary tools to identify and individualize a potentially aggressive dog.


Subject(s)
Dogs , Cuspid/anatomy & histology , Dogs/anatomy & histology , Jaw Relation Record/methods , Bite Force , Cephalometry/methods , Forensic Sciences/methods , Incisor/anatomy & histology , Veterinary Medicine/methods
5.
Rev. bras. plantas med ; 14(2): 362-369, 2012. ilus, tab
Article in Portuguese | LILACS | ID: lil-650679

ABSTRACT

O polvilho da fruta-de-lobo é um produto extraído da polpa da fruta-de-lobo verde (Solanum lycocarpum A. St.-Hil.), popularmente utilizado. Pouco se conhece a respeito desse polvilho, mas são atribuídos a ele vários efeitos terapêuticos, dentre eles a redução do colesterol. Este trabalho teve o objetivo de verificar a ação da administração do polvilho da fruta-de-lobo sobre animais hipercolesterolêmico. Utilizou-se 24 ratos Wistar fêmeas distribuídas em delineamento ao acaso, em três grupos contendo 8 animais em cada grupo. Estes grupos foram definidos como: controle normal (CN), controle hipocolesterolêmico (CH) e hipocolesterolêmico tratado (HT). O grupo CN recebeu dieta comercial, os grupo CH e HT receberam a dieta comercial enriquecida de colesterol e ácido cólico e o grupo HT recebeu também, 100 mg de polvilho da fruta-lobo, diariamente, por sonda orogástrica. O experimento teve uma duração de 6 semanas onde se avaliou o colesterol total sérico semanalmente, peso dos animais semanalmente e o consumo diário de ração. Ao término do experimento, foram avaliados os seguintes parâmetros: frações séricas de colesterol HDL, LDL+VLDL, peso do fígado, colesterol total hepático, lipídeos totais hepático e lâminas de microscopia foram feitas para avaliação dos hepatócitos. Não houve diferença significativa em relação ao peso corporal dos animais, ao consumo da dieta e nas análises de colesterol total sérico entre os grupos estudados. Avaliando-se a relação VLDL +LDL/HDL, os níveis encontrados no grupo HT foram significativamente menores que o grupo CH. Já em relação ao colesterol hepático, o grupo HT mostrou níveis menores de colesterol que o CH. Observou-se nos lipídeos hepáticos que não houve diferença significativa entre os grupo CH e HT, e no peso do fígado houve diferença significativa entre os grupos avaliados. Em relação à microscopia, os grupos hipercolesterolêmicos apresentaram discreta vacuolização no citoplasma dos hepatócitos. Concluiu-se, que o polvilho da fruta-de-lobo não influenciou o colesterol sérico dos animais, entretanto, reduziu os níveis de colesterol hepático.


The fruit-of-wolf flour is a product extracted from the pulp of green fruit-of-wolf (Solanum lycocarpum A. St .- Hil.) and is commonly used. Little is known about this flour, but several therapeutic effects, including cholesterol reduction, are attributed to it. This study aimed to verify the action of the administration of fruit-of-wolf flour to hypercholesterolemic animals. We used 24 female Wistar rats allocated in randomized design to three groups containing 8 animals each. These groups were defined as normal control (CN), hypocholesterolemic control (CH) and hypocholesterolemic treated rats (HT). The CN group received a commercial diet, while the CH and the HT group received the commercial diet enriched with cholesterol and cholic acid; the HT group also received 100 mg of fruit-of-wolf flour, daily, by orogastric tube. The experiment lasted for six weeks and the following characteristics were evaluated: weekly total serum cholesterol, weekly weight of animals and daily food intake. At the end of the experiment, we assessed the following parameters: serum cholesterol fractions HDL, LDL + VLDL, liver weight, liver total cholesterol, liver total lipids and microscopic slides were prepared for the evaluation of hepatocytes. There was no significant difference in body weight of animals, diet consumption and analysis of serum total cholesterol among the studied groups. Assessing the relationship VLDL + LDL / HDL, the levels found for the HT group were significantly lower than those for the CH group. As regards liver cholesterol, the HT group showed lower cholesterol levels than the CH group. For liver lipids there was no significant difference between the CH and the HT group, and for liver weight there was no significant difference among the studied groups. As to microscopy, the hypercholesterolemic groups showed slight vacuolization in the cytoplasm of hepatocytes. It was concluded that fruit-of-wolf flour did not influence the serum cholesterol of animals but reduced the levels of liver cholesterol.


Subject(s)
Animals , Female , Rats , Starch and Fecula , Anticholesteremic Agents/analysis , Cholesterol/pharmacology , Solanaceae/classification
6.
Braz. j. med. biol. res ; 40(5): 657-662, May 2007. tab
Article in English | LILACS | ID: lil-449088

ABSTRACT

The effects of schistosomiasis on microsomal enzymes were studied on post-infection day 90 when accumulated damage and fibrosis are most intense but granulomatous reaction around the eggs harbored in the liver is smaller than during the earlier phases. Swiss Webster (SW) and DBA/2 mice of either sex (N = 12 per sex per group) were infected with 100 Schistosoma mansoni cercariae on postnatal day 10 and killed on post-infection day 90. Cytochrome P-450 (CYP) concentration and alkoxyresorufin-O-dealkylases (EROD, MROD, BROD, and PROD), p-nitrophenol-hydroxylase (PNPH), coumarin-7-hydroxylase (COH), and UDP-glucuronosyltransferase (UGT) activities were measured in hepatic microsomes. Age-matched mice of the same sex and strain were used as controls. In S. mansoni-infected mice, CYP1A- and 2B-mediated activities (control = 100 percent) were reduced in SW (EROD: male (M) 36 percent, female (F) 38 percent; MROD: M 38 percent, F 39 percent; BROD: M 46 percent, F 19 percent; PROD: M 50 percent, F 28 percent) and DBA/2 mice (EROD: M 64 percent, F 58 percent; MROD: M 60 percent; BROD: F 49 percent; PROD: M 73 percent) while PNPH (CYP2E1) was decreased in SW (M 31 percent, F 38 percent) but not in DBA/2 mice. COH did not differ between infected and control DBA/2 and UGT, a phase-2 enzyme, was not altered by infection. In conclusion, chronic S. mansoni infection reduced total CYP content and all CYP-mediated activities evaluated in SW mice, including those catalyzed by CYP2E1 (PNPH), CYP1A (EROD, MROD) and 2B (BROD, PROD). In DBA/2 mice, however, CYP2A5- and 2E1-mediated activities remained unchanged while total CYP content and activities mediated by other CYP isoforms were depressed during chronic schistosomiasis.


Subject(s)
Animals , Female , Male , Mice , /metabolism , Liver Diseases, Parasitic/enzymology , Microsomes, Liver/enzymology , Schistosomiasis mansoni/enzymology , Chronic Disease , Mice, Inbred DBA , Microsomes, Liver/parasitology , Time Factors
7.
Braz. j. med. biol. res ; 38(1): 27-31, Jan. 2005. ilus
Article in English | LILACS | ID: lil-405550

ABSTRACT

The establishment of dorsal-ventral polarity in Drosophila is a complex process which involves the action of maternal and zygotically expressed genes. Interspecific differences in the expression pattern of some of these genes have been described in other species. Here we present the expression of dorsal-ventral genes during early embryogenesis in the lower dipteran Rhynchosciara americana. The expression of four genes, the ventralizing genes snail (sna) and twist (twi) and the dorsalizing genes decapentaplegic (dpp) and zerknüllt (zen), was investigated by whole-mount in situ hybridization. Sense and antisense mRNA were transcribed in vitro using UTP-digoxigenin and hybridized at 55°C with dechorionated fixed embryos. Staining was obtained with anti-digoxigenin alkaline phosphatase-conjugated antibody revealed with NBT-BCIP solution. The results showed that, in general, the spatial-temporal expression of R. americana dorsal-ventral genes is similar to that observed in Drosophila, where twi and sna are restricted to the ventral region, while dpp and zen are expressed in the dorsal side. The differences encountered were subtle and probably represent a particular aspect of dorsal-ventral axis determination in R. americana. In this lower dipteran sna is expressed slightly later than twi and dpp expression is expanded over the lateral ectoderm during cellular blastoderm stage. These data suggest that the establishment of dorsal-ventral polarity in R. americana embryos follows a program similar to that observed in Drosophila melanogaster.


Subject(s)
Animals , Female , Body Patterning/genetics , Central Nervous System/embryology , Diptera/embryology , Embryonic and Fetal Development/genetics , Gene Expression Regulation, Developmental/genetics , Genes, Insect/genetics , Diptera/genetics , Embryo, Nonmammalian/embryology , In Situ Hybridization , RNA, Messenger/genetics
8.
Rev. odonto ciênc ; 19(46): 367-371, out.-dez. 2004. tab
Article in Portuguese | LILACS, BBO | ID: lil-412485

ABSTRACT

O micronúcleo é uma porção de cromatina resultante de mitoses aberrantes que permanece próxima ao núcleo celular. A avaliação da freqüência desta alteração tem sido utilizada para medir o grau de injúria genotóxica ao qual células animais estão expostas. Neste estudo foram utilizadas as colorações de Feulgen e de Papanicolau com o objetivo de avaliar a freqüência de células micronucleadas e de micronúcleos na língua de indivíduos expostos ao etanol. Observou-se maiores freqüências de células micronucleadas e de micronúcleos nos indivíduos expostos ao etanol em relação ao grupo de controle em ambos os métodos de coloração. O método de Feulgen, no entanto detectou diferenças estatisticamente significativas entre os dois grupos de estudo tanto em relação às células micronucleadas quanto aos micronúcleos


Subject(s)
Humans , Micronuclei, Chromosome-Defective , Alcoholism , Mouth Neoplasms/etiology , Staining and Labeling , Age Factors , Sex Factors , Carcinogenicity Tests
9.
Braz. j. med. biol. res ; 36(1): 113-118, Jan. 2003. ilus, tab
Article in English | LILACS | ID: lil-326317

ABSTRACT

Annatto or urucum is an orange-yellow dye obtained from Bixa orellana seeds. It has been used as a natural dye in a variety of food products, drugs and cosmetics, and also in Brazilian cuisine as a condiment ('colorau'). Bixin, a carotenoid devoid of provitamin A activity, is the main pigment found in annatto. Some carotenoids (canthaxanthin, astaxanthin and á-Apo-8'-carotenal) are known to be potent inducers of CYP1A1, a property not shared by others (á-carotene, lycopene and lutein). Little is known, however, about the CYP1A1-inducing properties of bixin and annatto. The present study was performed to determine the effects of an annatto extract (28 percent bixin) and bixin (95 percent pure) on rat liver monooxygenases. Adult female Wistar rats were treated by gavage with daily doses of annatto (250 mg/kg body weight, which contains approximately 70 mg bixin/kg body weight), bixin (250 mg/kg body weight) or the vehicle only (corn oil, 3.75 g/kg body weight) for 5 consecutive days, or were not treated (untreated control). The activities of aniline-4-hydroxylase (A4H), ethoxycoumarin-O-deethylase (ECOD), ethoxy- (EROD), methoxy- (MROD), pentoxy- (PROD) and benzyloxy- (BROD) resorufin-O-dealkylases were measured in liver microsomes. Annatto (250 mg/kg containing 70 mg bixin/kg) induced EROD (3.8x), MROD (4.2x), BROD (3.3x) and PROD (2.4x). Bixin (250 mg/kg) was a weaker inducer of EROD (2.7x), MROD (2.3x) and BROD (1.9x) and did not alter PROD, A4H or ECOD activities. These results suggest that constituents of the extract other than bixin play an important role in the induction of CYP1A and CYP2B observed with annatto food colorings


Subject(s)
Animals , Female , Rats , Carotenoids , Liver , Microsomes, Liver , Mixed Function Oxygenases/drug effects , Plant Extracts , Enzyme Induction , Mixed Function Oxygenases/biosynthesis , Rats, Wistar
11.
Rev. cir. infant ; 12(2): 90-3, jun. 2002. ilus
Article in Spanish | LILACS | ID: lil-321182

ABSTRACT

Entre Enero de 1992 y marzo de 2000,67 pacientes con hipospadia distal subcoronal fueron operados por el mismo cirujano o alguno del equipo usando la técnica de Mathieu modificada.Las edades variaron entre 1 y 10 años(media 4,5 años)En 66 la técnica estandarizada se utilizó en forma primaria.Una técnica modificada de abordaje glandular se realizó en uno.Los resultados estéticos inmediatos y tardíos fueron buenos,A pesar que el número de pacientes fue reducido no hubo complicaciones mayores,La internación fue de hospital de día,disminuyendo la ansiedad de los niños que se retiraron sin catéter ni vendaje.El procedimiento en un tiempo,la cirugía precoz,los lentes de aumento y las suturas menos irritativas contribuyen al mejor resultado


Subject(s)
Infant , Child, Preschool , Child , Hypospadias , Kidney Tubules, Distal , Penis , Pediatrics
12.
Rev. cir. infant ; 11(3): 144-148, sept. 2001. tab
Article in Spanish | LILACS | ID: lil-320741

ABSTRACT

El objetivo de este estudio es el análisis de la mini toracotomóa y la toracoscopía videoasistida(TVA)en el manejo del empiema complicado en niños.Se realizó una revisión retrospectiva en 39 pacientes tratados en el Servicio de Pediatría Neumonológica y Cirugía Pediátrica del Hospital del Personal del Estado(HcSE)operados con mini toracotomía y toracoscopía videoasistida entre diciembre de 1990 y abril de 2001.Se estudió un total de 39 niños sin trastornos inmunológicos,con neumonía y empiema parameumónico,Todos los paciente requirieron intervención quirúrgica luego de un tratamiento con antibióticos y drenaje con toracotomía,drenaje imcompleto,pus tabicado y pulmón no expandido.Se realizaron 24 minitoracotomías entre diciembre de 1990 y marzo de 1998.Después de marzo de 1998,cuando se introdujo la TVA en nuestro servicio hasta abril de 2001 se realizaron 15 toracoscopías video asistidas.Los resultados han sido comparados con los del año anterior cuando se trataron casos similares con toracotomía abierta.Se estudiaron los progresos de estos 2 grupos de pacientes tratados con TVA o mini toracotomía.Todos los pacientes se recuperaron bien,con resolución de los síntomas y sin recurrencias


Subject(s)
Humans , Adolescent , Child , Empyema, Pleural , Pneumonia , Thoracic Surgery, Video-Assisted , Thoracoscopy , Pediatrics
13.
Rev. Soc. Bras. Med. Trop ; 34(4): 357-363, jul.-ago. 2001. graf, tab
Article in Portuguese | LILACS | ID: lil-461932

ABSTRACT

O objetivo do presente trabalho foi observar o desenvolvimento de R. neglectus em diferentes condições de temperatura e umidade. Três grupos foram formados:33/40 (33+/- 1ºC e 40% +/-5% UR), 33/70 (33+/- 1ºC e 70% +/-5% UR), e 28/70 (28+/- 1ºC e 70% +/-5% UR). Todos os grupos foram observados diariamente para avaliação do período de incubação dos ovos, período de desenvolvimento dos estádios ninfais, percentual de mortalidade por estádio, número de repastos realizados, e período de desenvolvimento da eclosão a muda imaginal. O desenvolvimento embrionário apresentou diferenças significativas em todos os tratamentos, o grupo 33/40 apresentou o menor período de incubação. O menor número de repastos foi observado no grupo 33/40 exceto para o primeiro estádio (grupo 28/70). O período de desenvolvimento ninfal foi significativamente reduzido no grupo 33/40; entretanto, o percentual de mortalidade deste grupo foi alto, e os insetos não conseguiram realizar a muda imaginal.


The objective of the present paper was to study the development of R. neglectus in the laboratory under different conditions of temperature and humidity. Three groups were prepared: 33/40 (33+/- 1 degree C and 40% +/-5% UR), 33/70 (33+/- 1 degree C and 70% +/-5% UR), and 28/70 (28+/- 1 degree C and 70% +/-5% UR). All these groups were observed daily to evaluate the eggs' incubation period, the development period of each instar nymph, the mortality rate of each stage, the frequency of feeding and the hatching - adult ecdysis period. The embryonic development showed significant differences between the treatment given, the group 33/40 presented the lowest incubation period. The lowest bloodmeals number was observed in the group 33/40 except for the first instar (group 28/70). The period of nymphal development was significantly reduced in the group 33/40, however, the mortality was high and the specimens did not reach the adult phase.


Subject(s)
Animals , Rhodnius/growth & development , Humidity , Temperature
14.
Indian J Physiol Pharmacol ; 2001 Apr; 45(2): 136-47
Article in English | IMSEAR | ID: sea-108798

ABSTRACT

The study of the genetic basis of human male infertility is complicated by genetic heterogeneity and because linkage analysis studies are difficult. The study has been limited so far to the analysis of genes located on the Y chromosome. Several genes and gene families have been discovered and mutation analysis of these candidate genes in infertile patients is ongoing. In recent years, several mouse models with impaired spermatogenesis or fertility have also been analysed, expanding our knowledge about the molecular basis of spermatogenesis and male fertility.


Subject(s)
Animals , Humans , Infertility, Male/etiology , Male , Mice , Models, Animal , Spermatogenesis , Y Chromosome
15.
Rev. cir. infant ; 10(4): 215-20, dic. 2000. ilus
Article in Spanish | LILACS | ID: lil-285357

ABSTRACT

Se realizó un estudio experimental con cerdos,para evaluar la funcionalidad y efectividad de una técnica quirúrgica en la corrección del reflujo vesicoureteral(RVU)La operación consistió en la confección de un colgajo de la mucosa vesical como válvula antirreflujo.Previamente se indujo RVU uni o bilateral,luego fue seleccionado al azar uno de los lados y corregido con esta técnica.Los cerdos fueron dividos en 3 grupos.Grupo A;4 cerdos a los que se indujo RVU bilateral y se corregió un lado sin quimioprofilaxis.Grupo B;2 cerdos con igual tratamiento que el A pero medicados con aminoglucósidos.Grupo C:3 cerdos con inducción unilateral del RVU,corregidos en forma inmediata y tratados como quimioprofilaxis.Sólo un cerdo tuvo RVU pequeño a la 4 semana,que desapareció a la 8 semana del postoperatorio.Todos fueron estudiados con cistouretrografía.La corrección del RVU con una válvula de mucosa de la propia vejiga resultó satisfactoria y funcional tal como la cirugía convencional,pero con la ventaja de requerir cistototomía mínima(5 cm).No hubo complicaciones por la movilización ureteral,la técnica permitió la manipulación endoscópica del ureter sin obstrucción y es válida como reoperación si otra falla


Subject(s)
Animals , Gallbladder , Surgical Flaps , Vesico-Ureteral Reflux/surgery , Surgery, Veterinary
16.
Rio de Janeiro; FIOCRUZ; 1998. 1109 p. ilus.
Monography in English | LILACS | ID: lil-235840

ABSTRACT

Habitats of Triatominae bugs are important from an epidemiological point of view. Each species is related to certain environmental conditions, and its significance as a vector for Trypanosoma cruzi is often linked to its proximity to human dwellings or the infestation of houses, corrals, pigeon or chicken coops, woodpiles, and/or other peridomiciliary sites. The authors of this chapter have agreed to provide a general list of references, mostly devoted either to those publications compiling the scattered bibliography or to some specific papers where a single species was studied, giving compiled bibliography added to the original research. Despite this bibliographical condensation, the list is long enough to provide a general idea about some basic references to each species


Subject(s)
Disease Vectors , Trypanosoma cruzi , Insect Vectors
17.
An. farm. quím. Säo Paulo ; 22(1/2): 35-41, 1982.
Article in Portuguese | LILACS | ID: lil-12464

ABSTRACT

Ratos Wistar machos, com 30 dias de idade, foram submetidos a intoxicacao experimental, com 100 ppm de HgCl2, por via oral.Os niveis de lipoperoxidacao hepatica e renal foram avaliados, medindo-se a quantidade total de malonildialdeido (MDA) produzido por homogenados desses orgaos. Nao se obteve nenhuma alteracao na quantidade de MDA produzida pelos homogenados. Cortes histologicos desses orgaos, nos animais tratados, nao mostraram alteracoes, quando comparados com os do grupo controle


Subject(s)
Male , Animals , Rats , Kidney , Lipid Peroxides , Liver , Malondialdehyde , Mercury Poisoning
18.
AMB rev. Assoc. Med. Bras ; 27(6): 187-9, 1981.
Article in Portuguese | LILACS | ID: lil-3303

ABSTRACT

Os autores apresentam um caso de atrofia hemifacial grave tratado com um retalho livre dermogorduroso desepitelizado transferido da regiao inguinocrural para a face com tecnica microcirurgica. Esta indicado nos casos em que a atrofia da hemiface e acentuada. Comentam a indicacao destes retalhos em relacao aos outros retalhos migrados e os detalhes da cirurgia e pos-operatorio


Subject(s)
Facial Hemiatrophy , Microsurgery , Surgical Flaps
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