Projeto en-red-versad@s-clube de poesia on- line- relato de uma experiência de utilização de um blogue por seniores portugueses e espanhóis / En-red- versad@s project-online poetry club- report of an experience of ising a blog by portuguese and spanish seniors

O presente relato é parte de um projeto mais vasto de intervenção e investigação em curso no âmbito do Projeto En­Red­Versad@s.Clube de poesia on line, dinamizado pela Universidade Sénior da Universidade da Corunha e pelo seu parceiro Programa 60+ do Politécnico de Leiria. Este clube visa, através da dinamização de um blogue, a divulgar a língua e a poesia portuguesas, bem como desenvolver competências linguísticas, culturais e digitais, através do domínio e uso das Tecnologias da Informação e Comunicação (TIC). O projeto desenvolve-se no quadro de uma educação plurilinguística, poética e digital, ao longo da vida, em ordem a um envelhecimento ativo e saudável, bem como à construção de uma cidadania consciente e comprometida por parte dos estudantes seniores. Através deste relato, pretende-se apresentar os objetivos, participantes, metodologias de ação e os primeiros dados de participação dos seniores, decorrentes do registo de acesso ao blogue e aos conteúdos partilhados, cuja análise se insere num paradigma quantitativo. Os resultados obtidos, através de estatístisca descritiva, sugerem que o projeto tem potencialidades formativas que impulsionam o envolvimento dos participantes seniores no clube de poesia on line, abrindo a discussão sobre as vantagens de um alargamento da sua participação e sobre as estratégias pedagógicas para a promover. Afirma-se como uma resposta socioeducativa válida, em ordem à valorização pessoal e intergeracional dos participantes.(AU)

This report is part of a broader intervention and research project integrated within the scope of the En­Red­Versad@s Project. Online poetry club. Such project is developed by the Senior University of the University of A Coruña and its partner Program 60+ at the Polytechnic of Leiria. Through a blog, this club aims to promote the Portuguese language and poetry, as well as develop linguistic, cultural and digital competences, increasing proficiency with technologies and computers. The project is developed within the framework of a multilingual, poetic and digital education, through the life course, in order to achieve an active and healthy aging, as well as construct a conscious and committed citizenship by the senior students. This report intends to present the aims, participants and methods of action, as well as the first data of participation from the seniors, including their access records to the blog and the contents shared. The analysis is based on a quantitative paradigm. The results, obtained through, descriptive statisticssuggest that the project has training opportunities that can enhance the involvement of senior participants in the online poetry club. This opens the discussion about the advantages of widening their participation and the pedagogical ways of promoting it. This arises as a valid socio-educational response, in order to enhance the personal and intergenerational value of the participants.(AU)

Pollen resources partitioning of stingless bees (Hymenoptera: Apidae) from the southern Atlantic forest

Meliponinae eusocial bees are among the most important pollinators in the Neotropics and their beekeeping has been growing as both recreational and economic activity. Information on the pollen preferences and niche overlap among species coexisting in the same location is still scarce. This study focused on the use of pollen resources by three native species of Meliponinae in the Atlantic Forest, Melipona quadrifasciata quadrifasciata (Lepeletier 1836), Scaptotrigona depilis (Moure 1942), and Tetragonisca angustula (Latreille 1811), at two different sites. The use of pollen resources was evaluated from reserves inside hives collected monthly between February 2015 and January 2016. It was also estimated the Mean Minimal Distance (Dm) traveled by the bees to obtain pollen. The bees differed regarding the diversity of pollen types, Dm, and proportion of pollen from different plant life-form. Local factor promoted differences only for Dm. M. q. quadrifasciata foraged a low diversity of pollen species and traveled greater distances with a higher proportion of trees plus palm species. Tetragonisca angustula foraged a higher diversity of pollen and flew shorter distances with a lower proportion of trees and palms. The species factor predominates over the local factor in the clustering pattern, based on pollen profile similarity.

Indicadores de desempenho e redes sociais: existe algo em comum? / Performance indicators and social networks: is there something in common?

Resumo Introdução Este artigo objetiva identificar a relação entre o desempenho de um Programa de Controle da Hanseníase (PCH) e a sua relação com a rede social, em um município brasileiro. Método Foram realizadas coleta de dados secundários, visitas para observação e entrevistas com o coordenador local do programa (PCH), o secretário de saúde, outros dois coordenadores e com profissionais por estes citados, seguindo a técnica de gerador de nomes. Dezesseis entrevistas originaram a elaboração de seis redes individuais e três coletivas, configurando três momentos: (I) identificação do problema, (II) demonstração do problema e (III) tentativa de reestruturação. Resultados Observou-se uma centralidade de cliques, em que o coordenador do PCH e o da Vigilância Epidemiológica compartilhavam funções no PCH, com fortes laços pessoais. As demais ligações identificadas foram caracterizadas como fortes ou frágeis, e profissionais. Conclusão Foi identificada relação entre o desempenho do PCH (indicadores) e os diferentes tempos das redes sociais, o que acabou por influenciar no funcionamento deste.

Abstract: Introduction The aim of this study is to identify the relation between the performance of a Leprosy Control Program (LCP) and the social network, in a municipality of the brazilian north/northeast region. Method The social network analysis methodology was used. The criteria for choosing the municipality were defined based on low performance of its LCP. The researchers visited the municipality to conduct observations, interviews and secondary data collection. The interviews began with the local coordinator of the program (LCP), the health secretary and two other coordinators. Further interviews were performed with the professionals cited by the "key-informants", resulted by the use of the name generator technique. Sixteen interviews were conducted with professionals that work directly with the LCP, and it allowed the elaboration of six personal networks and three collective networks. From these, the scenario of the program in three stages were drew up, based on the social network structures: (I) problem identification, (II) statement of problem, and (III) restructuring. Results It was found a "double-centrality", what means that the general coordinator of the LCP and general coordinator of Epidemiologic Surveillance shared functions in the program, with very strong personal ties. Other relations were characterized as strong or weak and professional. Conclusion It was identified a relation between the LCP performance and the different times of the social networks, which influenced the functionality of this.

4-Phenyl-1, 3-thiazole-2-amines as scaffolds for new antileishmanial agents

There is still a need for new alternatives in pharmacological therapy for neglected diseases, as the drugs available show high toxicity and parenteral administration. That is the case for the treatment of leishmaniasis, particularly to the cutaneous clinical form of the disease. In this study, we present the synthesis and biological screening of eight 4-phenyl-1,3-thiazol-2-amines assayed against Leishmania amazonensis. Herein we propose that these compounds are good starting points for the search of new antileishmanial drugs by demonstrating some of the structural aspects which could interfere with the observed activity, as well as suggesting potential macromolecular targets. Methods: The compounds were easily synthesized by the methodology of Hantzsch and Weber, had their purities determined by Gas Chromatography-Mass spectrometry and assayed against the promastigote forms of Leishmania amazonensis as well as against two white cell lines (L929 and THP-1) and the monkey's kidney Vero cells. PrestoBlue® and MTT viability assays were the methodologies applied to measure the antileishmanial and cytotoxic activities, respectively. A molecular modeling target fishing study was performed aiming to propose potential macromolecular targets which could explain the observed biological behavior. Results: Four out of the eight compounds tested exhibited important anti-promastigote activity associated with good selectivity indexes when considering Vero cells. For the most promising compound, compound 6, IC50 against promastigotes was 20.78 while SI was 5.69. Compounds 3 (IC50: 46.63 µM; SI: 26.11) and 4 (IC50: 53.12 µM; SI: 4.80) also presented important biological behavior. A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. Conclusions: This study shows that 4-phenyl-1,3-thiazol-2-amines could be good scaffolds to the development of new antileishmanial agents. The S-methyl-5-thioadenosine phosphorylase could be one of the macromolecular targets involved in the action.(AU)

Implante dentário: conhecimento da população baiana / Dental implant: level of knowledge of the bahia population

Desde os povos mais remotos, a humanidade preocupa-se com a estética e a sua associação com o sorriso, e consequentemente com a presença de dentes. Nos tempos mais primitivos, o homem experimentou e usou vários materiais na tentativa de repor seus dentes perdidos. não obtendo, no entanto, êxito na maioria das vezes. Modernamente os implantes dentários são produzidos em titânio, material que tem demonstrado ser altamente biocompatível, representando o mínimo de rejeição da interação organismo-corpo estranho e possibilitando reabilitar a população com os perfis mais variados de perdas dentárias. Porém o número de pacientes edêntulos total ou parcialmente tratados com o sistema de implante ósseo integrado, ainda é muito pequeno frente à grande massa desdentada da nossa população, o que nos faz questionar os motivos para tal distanciamento. Visando mensurar o nível de conhecimento da populaçao baiana acerca dos implantes dentários, o presente estudo utilizou-se de questionários fechados aplicados a 300 cidadãos da via pública de Salvador nos seguintes moldes: Grupo 1. Profissionais com nível superior de instrução; Grupo 2: Profissionais com nível médio de instrução e Grupo 3: Estudantes Universitários. Em nenhum dos grupos poderiam participar Dentistas ou Estudantes de Odontologia. Os resultados demonstraram que a maioria os três grupos analisados tem conhecimentos significativos sobre o assunto e sentem-se seguros à submissão da intervenção cirúrgica, mas o anseio do alto custo restringe a procura do serviço na maioria dos casos avaliados.

From the most remote people, the humanity worries about the aesthetics and your association with the smile, and consequently with the presence of teeth. In the most primitive times, the man tried and it used several materials in the attempt of restoring your lost teeth, not obtaining, however, success most of time. Now, dental implant are produced in tittanium, material that has been demonstrating be highly biocompatible, representing the minimum of bounce of the interaction strnge organism-body and making possible to rehabilitate the population with the most varied profiles of dental losses. However the number of patient total edentulous or partially agreements with the system of it implants bony integrated, it is still very small front to the great toothless mass of our population, the one that does question us the reasons for such estrangement. Seeking to measure the level of knowledge of the Bahia population concerning you dental implant, the present study was used applied questionares to 300 citizens of the public road of Salvador in the following molds: Group 1: Professsionals with superior level of instruction; Group 2: Professionals with medium level of instruction and Group 3: Academical students. In nome of the groups they could announce Dentists or Students of Dentistry. The results demonstrated that most of the three analyzed groups has significant knowledge on the subject and they feel safe to the submission of the surgical intervention, but the longing of the high cost restricts the search of the service in most of the appraised cases.

Ação do fluoreto de dentifrícios sobre o esmalte dentário / Action of the fluoride of the dentifrices on the dental enamel

A possibilidade de intervir na dissolução do esmalte dentário, diminuindo significativamente a perda de minerais, e de reverter o progresso de lesões cariosas iniciais torna o fluoreto um elemento indispensável à saúde dental. Enquanto recurso preventivo, o fluoreto é uma alternativa de saúde pública bucal extremamente eficaz e de baixo custo. Visando subsidiar a literatura que trata da eficácia do fluoreto de sódio (NaF), do monofluorfosfato de sódio (MFP) e da associação entre o fluoreto de sódio e o monofluorfosfato de sódio (NaF/MFP) que integram os dentifrícios, o presente trabalho teve por objetivo determinar, in vitro, o grau de proteção do esmalte dentário humano, assegurado por estas formas de fluoreto, frente à queda do pH. As taxas do cálcio liberado do esmalte previamente tratado, expressas em mg/dl/20min, revelaram o poder protetor destes fármacos. Os resultados experimentais comprovam que o fluoreto de sódio contido no dentifrício teste revelou maior proteção do esmalte, apesar da menor concentração deste fármaco em relação ao monofluorfosfato de sódio e à associação fluoreto de sódio/ monofluorfosfato de sódio, contidos nos demais. Tais conclusões sugerem a continuidade das experimentações, em face da importância de se obterem respostas eficazes, utilizando-se baixas concentrações da forma de fluoreto, comprovadamente mais efetiva, e de se realizar o controle de qualidade dos mais diversos produtos que são lançados no mercado freqüentemente.