ABSTRACT
To evaluate the efficacy and safety of combined Photodynamic therapy [PDT] with verteporfm and intravitreal triamicinolone acetonide [IVTA] treatment for subretinal neovascular membrane [SRN] secondary to type 2A-parafoveal telangiectasia. Retrospective, non-randomized pilot study of 80 eyes of 40 patients with type 2 PFT examined at our Institute, 6 patients had SRN, out of which 5 patients underwent PDT with verteporfin and IVTA. PDT was applied according to standard protocol. Intravitreal injection of 4 mg of TA. The main outcome measures were visual acuity [VA], the safety issues and the retreatment frequency with the combined treatment Fifteen percent of patients with type 2 A PFT had SRN. Mean follow up period was 11.8 months [range 6 to 14 months]. Mean lesion size was 2580micro, [1000 micro -4800 micro]. Three patients had improvement in VA that is >/= 2 line [Snellen] gain. Two patients maintained stable VA; stable VA was defined as unchanged vision or = 1 line decrease from baseline value. One patient had recurrence of SRN at the end of 3 months. He underwent repeat PDT with IVTA and had stable vision [1 line gain] until last follow up. One patient developed moderate increase in intraocular pressure and was treated with beta-blockers. Two patients had preexisting cataractous changes. Combination treatment for SRN secondary to Type 2 A PFT appears to be effective and safe mode of management, rather than a stand alone PDT treatment for this disorder. It also reduces the recurrence rate after treatment
ABSTRACT
Scanning laser ophthalmoscope-optical coherence tomography [SLO-OCT] a combined innovative technology provides high-resolution, in depth images of the retina and SLO scans the retina to locate the area of the disease using a single source. The two scanning modes has enabled in better understanding of the extent of disease and aid physician with diagnostic challenges. It is useful in localizing accurately subtle pathology with enhancement of vitreo-retinal interface. The coronal scans are particularly useful to study the retinal pigment epithelial - choriocapillary interface pathology and verify subtle lesions noticed on cross sectional scans. Its ability to scan in undilated pupils is another advantage but requires utmost patient's cooperation. Little ocular movement causes difficulties in obtaining the image, also inability to scan in high myopes. The ability to fuse with other imaging system in future would make SLO-OCT a versatile compact diagnostic tool in the management of posterior segment pathology