ABSTRACT
Objective To summary MRI features of children syringohydromyelia in primary tethered cord syndrome and analyze the correlation.Methods 84 syringohydromyelia cases were analyzed retrospectively.The imaging features of syringohydromyelia including the location,the size and the shape,the syrinx index and so on were analyzed,and the correlation of syringohydromyelia with various diseases which caused tethered cord syndrome were analyzed simultaneously.Results The central canal of the spinal cord was filiform in 1 5 cases,fine tubular in 21 cases and cystic dilatation in 48 cases.There were no relation to the length and width with the age.There was statistically significance in syrinx index(>40%)with diastematomyelia(P =0.017),and no relation to other types of tethered cord syndrome.Diastematomyelia and myelocele were risk factors for cystic dilatation of syringohydromyelia.Conclusion Diastematomyelia and myelocele have a higher incidence in cystic dilatation of syringohydromyelia than that in other types of tethered cord syndrome,and diastematomyelia is more common in association with bigger syrinx index of syringohydromyelia.
ABSTRACT
Purpose To study the MRI manifestations of hippocampus with acute injury in children with epilepsy, and to explore its causes and outcomes for a better understanding of the changes of hippocampal structure with acute injury.Materials and Methods The clinical and imaging data of 8 children with epilepsy whose hippocampus showed hyperintensity in DWI were retrospectively analyzed. The bilateral hippocampal volume and ADC values were measured; changes of hippocampal volume and T2WI signal and ADC value were also analyzed.Results Eight patients were clinically diagnosed as epilepsy, 7 cases had recurrent history of seizures. MRI was performed from 1 to 5 days after the onset of epilepsy. All the 8 patients had increased unilateral hippocampal volume, 6 of whom were on the left side and the other 2 were on the right side. The affected ipsilateral hippocampal volume was significantly higher than that on the contralateral side [(2.096±0.570) cm3 and (1.768±0.447) cm3, respectively,t=-4.763,P<0.01]. The signals increased on T2WI and FLAIR; DWI showed hyperintensity with increase by approximately 25.52%. The affected ipsilateral ADC value was significantly lower than the contralateral one [(0.763±0.049)×10-3 mm2/s and (0.859±0.054)×10-3 mm2/s, respectively, t=9.598,P<0.01]. No abnormalities were found in bilateral hippocampus when 3 patients underwent MRI due to febrile convulsions and seizures before the onset of epilepsy. The affected ipsilateral hippocampal volume reduced in 3 patients after 3 to 5 months;signal was still high on T2WI and FLAIR; ADC values increased by 15.6%, the imaging results indicated hippocampal sclerosis.Conclusion Epilepsy can cause acute injury in hippocampus which demonstrates hippocampus swelling, signal increase on T2WI, and reduced ADC value and may lead to hippocampal sclerosis.