ABSTRACT
Background: Nasal polyposis are considered a sign or a physical finding rather than a disease resulting from a complex process that is found in some individuals, such as people suffering from chronic sinusitis, rhinitis, Kartagener's syndrome, or cystic fibrosis. Sinonasal polyps can have four distinct histological subtypes, which include eosinophilic polyp, chronic inflammatory polyp, hyperplastic polyp, and polyp with stromal atypia
Aim: In this review, we aim to study the presentation, classification and diagnosis of nasal polyps in the light of histopathological findings
Materials and methods: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 2001, through February 2017. The following search terms were used: nasal polyp, inflammation of nasal mucosa, chronic inflammation, histology of nasal mucosa, pathology of nasal polyps
Conclusion: Polyposis does not have histological problems and complications. However, they may be clinically disturbing. Polyps are not classified into allergic and non-allergic, and are rather stratified according to histological findings, making histological investigation crucial for diagnosis
ABSTRACT
Introduction: anemia of chronic disease has a widespread impact on patients with chronic disorders such as chronic inflammation, infection, malignancy etc. The pathophysiology behind it is largely due to involvement of hepcidin levels which are high as a result of the underlying chronic disorder, but negatively affects iron metabolism and erythropoiesis
Aim of the work: we tried to understand the pathogenesis, impact, diagnosis, and management of anemia due to chronic diseases
Methodology: we conducted this review using a comprehensive search of MEDLINE, PubMed and EMBASE from January 2001 to March 2017. The following search terms were used: anemia of chronic disease, anemia of inflammation, types of anemia, management of chronic anemia
Conclusion: since absolute treatment for the underlying chronic conditions are not available, various other modalities aimed at treating the anemia are developing. They include conventional and novel therapies. More researches must be done in order to manage the condition by treating the underlying cause, or for finding therapies with least side effects