ABSTRACT
Abstract Objective: To determine the prevalence of nasal septum perforation associated to Histoplasma sp. Material and Methods: A retrospective descriptive study was conducted with patients who developed nasal septum perforation associated to histoplasmosis. The diagnosis was made based on clinical manifestations and confirmed with mycological direct examination with Giemsa stain, culture, serologic tests (immunodiffusion method), and histopathology with hematoxylin-eosin, Grocott methenamine (GMS) and Periodic Acid-Schiff stain (PAS). Results: Out of 1654 medical records reviewed with diagnosis of histoplasmosis in the study period, we found 22 cases with nasal septum perforation. Autoimmune disease was present in 6 patients; all six were on immunosuppressive treatment. Two patients had HIV/AIDS, one of them had also paracoccidiodomycoses and the remaining had no apparent underlying disease or conditions. Conclusion: Physicians of endemic areas such as Venezuela, must consider this entity in the differential diagnosis with other diseases.
Subject(s)
Humans , Male , Female , Acquired Immunodeficiency Syndrome/pathology , Diagnosis, Differential , Nasal Septal Perforation/diagnostic imaging , Immunosuppressive Agents/therapeutic use , Mycoses/pathology , Autoimmune Diseases/pathology , Venezuela/epidemiology , Medical Records , Epidemiology, Descriptive , Retrospective StudiesABSTRACT
La dinámica de grupos permitió que 77 estudiantes del curso regular de Medicina Tropical, efectuaran durante cuatro años, un ensayo sobre la docencia en medicina centrada en el estudiante, mediante la participación en la publicación de artículos médicos en revistas científicas indexadas. Se publicaron 21 artículos: cuatro de investigación clínica, trece de investigación bibliográfica y cuatro de investigación docente con 27 estudiantes que participaron como autores. Se revisaron 823 referencias bibliográficas en la elaboración de los artículos: 20 por ciento de autores venezolanos y 80 por ciento de extranjeros. La ejecución de la experiencia permitió a los estudiantes adquirir destrezas y habilidades en el manejo eficiente de la información bibliográfica, cuando se elaboraron los artículos médicos. Enseñar medicina significa también aprender a publicar la información que va generando la investigación clínica y docente. El propósito fue el de narrar, evaluar y analizar una experiencia docente en la Cátedra de Medicina Tropical
The group dynamics strategy permitted that 77 students from the regular Tropical Medicine course during a four year period, carry out an assay about Teaching Medicine centered on the student, by means of participating and writing medical papers published in indexed medical journals. Twenty one papers were published: four on clinical investigation, thirteen reviews and four on teaching investigation, with 27 students participating as authors. For the publication of the mentioned papers, 823 references were revised: 20 percent corresponded to Venezuelan authors and 80 percent were from other countries. Participating in this experience permitted to the students the practice of capacities and skills related to reference revision applied to writing medical papers. Teaching medicine means also, learning how to publish the data generated during clinical and the teaching practices. The aim was to describe, analyze and evaluate a teaching experience in the Tropical Medicine Department