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Rev. invest. clín ; 57(5): 691-694, sep.-oct. 2005. ilus
Article in Spanish | LILACS | ID: lil-632450

ABSTRACT

Current findings suggest that more attention needs to be given to the increase in body mass being achieved by disabled populations in general and individuals with mental retardation in particular, to minimize long-term negative health consequences. Given that physical activity programs have been reported as one of the most effective ways of improving the health of individuals with Down syndrome, it would be of interest facilitate different tools to contribute to their clinical follow-up. Consequently, this study was designed to assess the correlation between anthropometrical parameters and lipid profile in adolescents with Down syndrome. Anthropometric variables such as body mass index, waist circumference and waist-to-hip ratio as well as serum lipids (total cholesterol, high-density-lipoprotein cholesterol, total-choles-terol/high-density-lipoprotein cholesterol and triglycerides) were measured in 21 male adolescents (16.3 ± 1.1 years) with Down syndrome. Anthropometric parameters presented a positive association with serum lipids except for high-density-lipoprotein cholesterol that was negative. It should be emphasized the strongest association of waist-to-hip ratio to total cholesterol/high-density-lipoprotein cholesterol ratio (r = 0.48; p < 0.05). It is concluded waist circumference and waist-to-hip ratio may be highly recommended in clinical practice as appropriate anthropometric predictors of lipid profile in adolescents with Down syndrome. Further studies are required to assess their behavior during physical activity programs as well as to determine more correlations in these individuals.


Si la obesidad como epidemia está alcanzando cotas preocupantes en la población general, la situación es aún más alarmante entre poblaciones con retraso mental en general y síndrome de Down en particular. Afortunadamente, recientes estudios sugieren que los programas de actividad física parecen una buena estrategia para combatirla, especialmente a edades tempranas. Para facilitar el seguimiento clínico de los mismos, diseñamos este trabajo para determinar las correlaciones más significativas entre parámetros antropométricos (índice masa corporal; índice cintura cadera; perímetro cadera) y el perfil lipídico sérico (colesterol total; colesterol-HDL; ratio colesterol total/HDL; triglicéridos) de 21 jóvenes adolescentes (16.3 ± 1.1) con trisomía 21. El coeficiente de correlación de Pearson demostró que las variables antropométricas ensayadas mostraron una correlación positiva con los distintos parámetros lipidicos excepto para colesterol-HDL que fue negativa. En líneas generales el perímetro de la cintura mostró el mejor comportamiento, mientras el índice cintura cadera mostró la mayor fuerza de asociación con la ratio colesterol-total/colesterol-HDL (r = 0.48; p < 0.05). Futuros estudios en los que se confirme la utilidad de estos hallazgos durante la aplicación de programas de actividad física y en los que se evalúen nuevas asociaciones son necesarios para contribuir a un mejor seguimiento y manejo de estos pacientes.


Subject(s)
Adolescent , Humans , Male , Body Mass Index , Cholesterol/blood , Down Syndrome/blood , Triglycerides/blood , Waist-Hip Ratio , Anthropometry
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