ABSTRACT
Paediatric UTI is a matter of grave concern particularly at less than two years of age due to predisposition to serious future complications and limited treatment options resulting from ever-increasing antibiotic resistance. This study included 392 established cases of paediatric UTI. Gram negative bacteria were isolated in 68.9% cases, predominated by Escherichia coli(34.7%). It was followed by Klebsiella species(27.3%), Enterococcus faecalis(12.2%), Acinetobacter species(7.4%), Pseudomonas aeruginosa(4.3%), and other GNB. Staphylococcus saprophyticus(4.1%) and Staphylococcus aureus(3.1%) were less common. Antibiograms of the isolates showed very low sensitivity to all commonly prescribed antibiotics, namely, ampicillin, amoxyclav, ceftriaxone, cefotaxime, gentamicin, cotrimoxazole, nitrofurantoin, ciprofloxacin and levofloxacin- making them practically irrational to choose. Most of the GNB were susceptible to imipenem, whereas, gram positive cocci were uniformly susceptible to vancomycin and linezolid