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1.
Arch. cardiol. Méx ; 93(1): 53-61, ene.-mar. 2023. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1429705

ABSTRACT

Abstract Objective: The purpose was to compare the outcomes of patients with ST-elevation myocardial infarction and multivessel coronary artery disease undergoing one-time multivessel revascularization (OTMVR) versus in-hospital staged complete revascularization with percutaneous coronary intervention. Methods: This was a single-center, retrospective, observational, and cohort study, including data from January 2013 to April 2019. A total of 634 patients were included in the study. Comparisons were made between patients who underwent in-hospital staged complete revascularization versus OTMVR. The primary endpoint was all-cause in-hospital mortality, secondary endpoints included cardiovascular complications, all-cause new hospitalization, and mortality evaluated at 30 days and 1 year. In addition, we constructed a logistic regression model for determining the risk factors that predicted mortality. Results: Of the 634 patients, 328 were treated with staged revascularization and 306 with OTMVR. About 76.7% were men, with a mean age of 63.3 years. Less complex coronary lesions and a higher proportion of the left anterior descending artery as the culprit vessel were found in the OTMVR group. Compared with staged revascularization, the primary and secondary endpoints occurred less frequently with OTMVR strategy. Conclusions: OTMVR did not generate more complications and demonstrate better clinical outcomes than in-hospital staged revascularization.


Resumen Objetivo: El propósito fue comparar resultados de pacientes con infarto agudo de miocardio con elevación del segmento ST y enfermedad coronaria multivaso sometidos a revascularización completa de un solo momento frente a revascularización completa por etapas mediante intervención coronaria percutánea. Métodos: Estudio cohorte observacional, retrospectivo, unicéntrico, con datos de enero de 2013 a abril de 2019, incluyendo 634 pacientes. Se compararon resultados entre pacientes sometidos a revascularización completa por etapas frente a revascularización completa en un solo momento. El objetivo primario fue valorar mortalidad intrahospitalaria por cualquier causa y como objetivos secundarios se evaluaron a 30 días y 1 año las complicaciones cardiovasculares, hospitalizaciones y mortalidad. Se construyó un modelo de regresión logística para determinar los factores de riesgo que predijeron mortalidad. Resultados: De 634 pacientes, 328 fueron tratados con revascularización por etapas y 306 con revascularización en una intervención. El 76.7% fueron hombres, con una media de edad de 63.3 años. En el grupo de revascularización de un solo tiempo se encontraron lesiones coronarias menos complejas y una mayor proporción de la arteria descendente anterior como vaso culpable. Comparado con el grupo de revascularización por etapas, los objetivos primarios y secundarios ocurrieron con menos frecuencia en el grupo de revascularización en un solo tiempo. Conclusiones: Comparada con la revascularización intrahospitalaria por etapas, la revascularización en una intervención lleva a mejores desenlaces clínicos sin generar más complicaciones.

2.
Rev. chil. ortop. traumatol ; 62(1): 66-73, mar. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1342679

ABSTRACT

El esquí es un deporte individual con una tasa de lesiones de 1,84 por 1.000 días esquiador en la población general. Las roturas del ligamento cruzado anterior (LCA) son algunas de las más comunes, llegando a una tasa de 5 por cada 100 esquiadores por temporada a nivel competitivo, debido a la gran exigencia a la que se encuentran sometidas las rodillas. Lo anterior presenta un desafío para el traumatólogo a la hora de plantear un manejo. Se realizó una revisión de la literatura respecto de los mecanismos de lesión, tratamiento, prevención, rehabilitación y uso de órtesis en el retorno deportivo. Se describen los mecanismos clásicos de lesión en esquiadores amateurs y competitivos. La mayoría de las lesiones de LCA son de resolución quirúrgica, en que la recomendación de reconstrucción debe ser con injerto autólogo de hueso-tendón patelar-hueso, salvo en los pacientes mayores o en pacientes con fisis abierta, en los que se recomienda el uso de injerto autólogo de semitendinoso-gracilis. La prevención y rehabilitación se basan en mejorar la fuerza y el control neuromuscular de los estabilizadores dinámicos de la rodilla implementándose programas específicos, evaluación del gesto deportivo, y pruebas de control neuromuscular. Se recomienda el uso de órtesis funcionales adecuadas en los pacientes sometidos a reconstrucción del LCA. Las lesiones de LCA en esquiadores de nivel competitivo son habituales, de manejo específico y multidisciplinario. La elección del injerto y del tipo de rehabilitación son fundamentales en el retorno deportivo del esquiador. NIVEL DE EVIDENCIA: V.


Skiing is an individual sport with an injury rate of 1.84 per 1,000 skier days among the general population. Anterior cruciate ligament (ACL) tears are among the most common injuries in skiers, with a rate of 5 per 100 skiers per season at a competitive level, because of the great demand placed on the knees. Their treatment is a challenge for orthopedic surgeons. A review of the literature was carried out regarding injury mechanisms, treatment, prevention, rehabilitation, and the use of bracing in the return to sports. The classic injury mechanisms in amateur and competitive skiers are described. Most ACL injuries require surgical resolution, with reconstruction using autologous bone-patellar tendon-bone graft, except in older patients or those with open physis, who must receive an autologous semitendinosusgracilis graft. Prevention and rehabilitation are based on improving strength and neuromuscular control of the dynamic knee stabilizers, implementing specific programs, evaluating the sport movements, and performing neuromuscular control tests. Suitable functional bracings are recommended in patients undergoing ACL reconstruction. ACL injuries in competitive-level skiers are common, and their management is specific and multidisciplinary. The choice of graft and rehabilitation type is critical to resume skiing. LEVEL OF EVIDENCE: V.


Subject(s)
Humans , Skiing , Anterior Cruciate Ligament Injuries/therapy , Orthotic Devices , Return to Sport , Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament Injuries/prevention & control , Anterior Cruciate Ligament Injuries/rehabilitation
3.
Mem. Inst. Oswaldo Cruz ; 116: e210210, 2021. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1360596

ABSTRACT

BACKGROUND Loa loa is a filarial species found exclusively in West and Central Africa. Microscopy is the traditional diagnosis method for human loiasis. Several molecular methods have developed as an alternative approach for identification of L. loa filarial parasites. OBJECTIVES The aim of this study was to evaluate a Loa-Loop-mediated isothermal amplification (LAMP) assay to diagnose loiasis disease on dried blood spots (DBS) samples, compared to microscopy, filaria-real time-polymerase chain reaction (PCR) and nested-Loa PCR. METHODS A total of 100 DBS samples and 100 blood smears were used for this study. DNA was extracted using saponin/Chelex method. DNA isolated was assayed by a Loa-LAMP assay in parallel to microscopy, filaria-real time PCR and nested-Loa PCR. The sensitivities and specificities of Loa-LAMP assay was computed comparing to each one of the reference methods. FINDINGS Loa-LAMP's sensitivity was more than 90% and specificity was nearly 100% when compared to molecular methods. On the other hand, sensitivity was decreased a bit when Loa-LAMP faced microscopy, but keeping the other statistical values high. MAIN CONCLUSIONS Loa-LAMP is an appropriate method for loiasis diagnosis in endemic areas. Though, it has disadvantages like the reagents' high price at the moment and not to be able to detect more filarial species at once.

4.
Rev. Fac. Cienc. Méd. (Quito) ; 45(2): 35-40, Dic 31, 2020.
Article in Spanish | LILACS | ID: biblio-1526408

ABSTRACT

Introducción: Las lesiones por trauma del cuello pueden ser abiertas o cerradas y a su vez se clasifican en superficiales y profundas. La decisión quirúrgica depende de la determinación del compromiso de órganos vitales. Objetivo: Determinar la importancia del conocimiento de estructuras anatómicas que conforman el cuello para establecer la trayectoria de la herida.Presentación del caso: Se reporta el caso de un paciente masculino de 27 años, quien recibe herida cortante en el cuello. El paciente exhibía una herida extensa de tipo superficial en la zona II del cuello, cuya gravedad corresponde al grado 1, por tanto, se suturó la herida, luego se envió al paciente a su domicilio y control posterior para retiro de puntos. Los aspectos médicos legales en el presente caso van encaminados a brindar información relevante respecto al compromiso o no de algún órgano vital o grandes vasos, dicha información facilita al señor fiscal para el establecimiento del tipo penal. Discusión: Es importante la presentación del caso ya que nos permite establecer el tratamiento médico que debe recibir el paciente en caso de heridas de cuello y su importancia médico legal para el establecimiento de un delito.Conclusiones: El conocimiento de las estructuras anatómicas que conforman el cuello determinan el trayecto de la herida y permite un tratamiento correcto en el manejo médico legal.


Introduction: Neck trauma injuries can be open or closed and in turn are classified as superficial and deep. The surgical decision depends on the determination of the commitment of vital organs. Objective: Determine the importance of anatomical knowledge of the neck to establish the trajectory of the wound.Case Presentation: The case of a 27-year-old patient is reported, who is attacked with a knife to the neck. The patient exhi-bited an extensive cutting wound of a superficial type in zone II of the neck, the severity of which corresponds to grade 1, therefore, the wound was sutured, then the patient was sent home and subsequent monitoring for removal of stitches. The medico-legal aspects in this case are aimed at providing relevant information regarding the commitment or not of a vital organ or large vessels, such information facilitates the prosecutor for the establishment of the criminal type. Discussion: The presentation of the case is important since it allows us to establish what medical treatment the patient should receive in case of neck injuries and the medical-legal importance of it for the establishment of a crime.Conclusions: The anatomical knowledge of the neck determines the trajectory of the wound and allows to stablish an appropriate treatment in legal medical management.


Subject(s)
Humans , Male , Adult , Wounds and Injuries , Forensic Medicine , Neck , Coroners and Medical Examiners , Plastic Surgery Procedures , Crime
5.
Acta neurol. colomb ; 36(3): 201-209, jul.-set. 2020. graf
Article in Spanish | LILACS | ID: biblio-1130714

ABSTRACT

RESUMEN Desde la década de 1970, la disponibilidad de neuroimágenes estructurales (tomografia computarizada y resonancia magnética) y funcionales como la tomografía computarizada por emisión de fotón único (SPECT), la tomografia por emisión de positrones (PET) o la resonancia magnética funcional (fMRI)), abrió una nueva via en el estudio de la relación bidireccional que existe entre los fenómenos comportamentales y la actividad neuronal. La introducción de estas técnicas condujo a una mejor comprensión del impacto de una lesión cerebral en la actividad cortical y en el desarrollo de síntomas psiquiátricos. Explicar la presencia de síntomas afectivos como una alteración en la función de una estructura cerebral es insuficiente, y se debe considerar siempre un compromiso de los circuitos cerebrales. Muchos trastornos del afecto se han asociado con lesiones en las conexiones talamolímbicas, incluyendo trastorno depresivo mayor, trastorno obsesivo-compulsivo, adicción a sustancias psicoactivas y trastorno de estrés postraumático, por lo que la identificación de los tractos de conectividad puede proporcionar nuevos medios para una intervención terapéutica eficaz.


SUMMARY Since the 1970s, the availability of structural neuroimaging (computed tomography and magnetic resonance imaging) and functional neuroimaging (single photon emission computed tomography (SPECT), positron emission tomography (PET), functional magnetic resonance imaging (fMRI)), has opened a new way in the study of the bidirectional relationship between behavioral phenomena and neuronal activity. The introduction of these techniques led to a better understanding of the impact of a brain injury on cortical activity and on the development of psychiatric symptoms. It is difficult to explain affective symptoms as a consequence of a brain structure dysfunction and is important to consider a brain circuit impairment. Many affective disorders have been associated with lesions in thalamolymbic connections, including major depressive disorder, obsessive-compulsive disorder, addiction to psychoactive substances and post-traumatic stress disorder, and the identification of the connectivity tracts can provide new means for effective therapeutic intervention.


Subject(s)
Transit-Oriented Development
6.
Rev. cuba. med. mil ; 49(2): e525, abr.-jun. 2020.
Article in Spanish | LILACS, CUMED | ID: biblio-1139004

ABSTRACT

Experiencias y reflexiones del Dr. José Hernán Salas Rubio, presentadas en forma de conferencia, en el Congreso Internacional Neuro-Cuba 2017. Es profesor titular y consultante, uno de los más prominentes neurocirujanos cubanos. Ha trabajado como neurocirujano desde 1962 y contribuido a la formación de jóvenes neurocirujanos. Ha publicado cinco libros y más de cincuenta artículos científicos(AU)


Experiences and reflections of Dr. José Hernán Salas Rubio, presented as a lecture, at the Neuro-Cuba International Congress 2017. He is a full professor and consultant, one of the most prominent Cuban neurosurgeons. He has worked as a neurosurgeon since 1962 and contributed to the training of young neurosurgeons. He has published five books and more than fifty scientific articles(AU)


Subject(s)
Humans , Male , Female , Neurosurgeons/history , Mentors/history , Consultants
7.
Arch. argent. pediatr ; 117(1): 68-71, feb. 2019. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-983784

ABSTRACT

Los schwannomas son tumores que se originan de las células de Schwann de los nervios periféricos. Su localización en el colon es extremadamente rara y no se han descrito, en la literatura, casos en niños. Por lo general, estos tumores son asintomáticos, pero pueden producir síntomas inespecíficos y gastrointestinales. La presentación como invaginación intestinal es muy infrecuente. Se expone el caso clínico de una paciente de 11 años de edad con un schwannoma de colon manifestado clínicamente como invaginación intestinal de sigma con dolor abdominal, rectorragia y estreñimiento de 10 días de evolución, que precisó resección intestinal con márgenes quirúrgicos libres, con buena evolución posoperatoria.


Schwannomas are tumours originating in the Schwann cells of the peripheral nerves. The appearance in the colon is extremely rare, and there are no known cases in the literature of schwannomas of the colon and rectum described in children. These tumours are usually asymptomatic, but can produce non-specific and gastrointestinal symptoms. The clinical presentation as intestinal intussusception is infrequent. We present a case of an 11-year-old girl with sigmoid swchannoma presented clinically as a colonic intussusception with abdominal pain, rectal bleeding and constipation of 10 days. An intestinal resection with free surgical margins was performed.


Subject(s)
Humans , Female , Child , Colon, Sigmoid , Gastrointestinal Neoplasms , Intussusception , Neurilemmoma
8.
Liberabit ; 22(1): 7-19, ene.-jun.2016. tab, graf
Article in Spanish | LILACS, LIPECS | ID: lil-790688

ABSTRACT

El objetivo del estudio fue evaluar los factores psicosociales en el trabajo del personal de justicia de la Comunidad Valencia (España) para identificar la prevalencia de riesgos psicosociales. Participaron 402 trabajadores (28.11 % hombres) incluyendo gestores, tramitadores y auxiliares sociales. Se evaluó con la Batería UNIPSICO (incluye factores de demanda, factores de recursos y consecuencias de los riesgos psicosociales). Los principales riesgos fueron la sobrecarga de trabajo (46.02 % de participantes en situación de alto riesgo) dentro de las demandas, la falta de recursos para realizar el trabajo (76.37 % en situación de alto riesgo) y la falta de autonomía (67.41 % en situación de alto riesgo). Para las consecuencias, el 61.44 % de participantes expresó insatisfacción laboral y un 27.11 % tuvo que consumir con frecuencia medicamentos en el último año por problemas de salud derivados del trabajo. Se concluye recomendando estrategias de intervención psicosocial para mejorar las condiciones de trabajo...


The objective of the study was to evaluate the psychosocial factors in the work of the justice personnel of Valencia (Spain) to identify the prevalence of psychosocial risks. The participants were 402 workers (28.11 % men) including managers, processors, and social assistants. We assessed using the UNIPSICO questionnaire (includes demand factors, resource factors, and consequences of psychosocial risks). The main risks were work overload (46.02 % of participants in a high risk situation) within the demands; the lack of resources to carry out the work (76.37 % in a high risk situation); and the lack of autonomy (67.41 % in a high risk situation). For the consequences, 61.44 % of participants expressed labor dissatisfaction, and 27.11 % had to frequently consume drugs in the last year because of health problems arising from work. We conclude by recommending psychosocial intervention strategies to improve working conditions...


Subject(s)
Humans , Burnout, Professional , Burnout, Professional/psychology , Burnout, Professional/therapy , Risk Factors , Psychology, Social
10.
Gac. méd. espirit ; 16(1): 40-49, ene.-abr. 2014.
Article in Spanish | LILACS | ID: lil-705626

ABSTRACT

Fundamento: los tumores fibrosos localizados de pleura son raros, de etiología incierta; la mayoría de los pacientes con esta enfermedad sobrepasan la quinta década de vida y más de la mitad están asintomáticos al diagnóstico, principalmente cuando los tumores son pequeños. Objetivo: describir el caso de una paciente con tumor fibroso localizado de pleura que, por su edad, sintomatología y por las características histológicas del tumor, representa una situación clínica infrecuente, con dificultades para el diagnóstico. Presentación de caso: mujer saludable, de 39 años, con dolor tóraco-lumbar persistente, de un año de evolución; en radiografía de tórax se visualizó imagen retro cardíaca izquierda corroborada por tomografía computarizada. Se realizó exéresis total de una masa de 4,8 cm, pedunculada, con origen en la pleura visceral, cuyo diagnóstico histopatológico fue un tumor fibroso localizado de pleura con características quísticas. Después de varios meses de seguimiento la paciente permanecía saludable y sin signos de recurrencia. Conclusiones: este caso constituye una forma infrecuente de presentación del tumor fibroso localizado de pleura por tratarse de una paciente menor de 40 años, con una sintomatología no frecuente y por el comportamiento benigno que ha tenido el tumor aunque presentó características quísticas.


Background: localized fibrous tumors of the pleura are rare, with uncertain etiology; most of the patients with this disease exceed the fifth decade of life and more than a half are without symptoms at the diagnosis, mainly when tumors are small. Objective: to describe a case of a female patient with a diagnosis of a localized fibrous tumor of pleura in which due to her age, the symptomatology and histological features of the tumor, it represents an infrequent clinical situation with difficulties for the diagnosis. Case presentation: a 39-year-old healthy woman with one year history of persistent thoracic lumbar pain; in chest radiography a left retrocardiac image was observed and it was corroborated by chest CT scan. Total exeresis was performed in a 4.8 cm mass, pedunculated, originating from the visceral pleura, whose histopathological diagnosis was a localized fibrous tumor of the pleura with cystic features. After several months of follow-up, the patient remained healthy and did not show recurrent signs. Conclusions: this case is an infrequent presentation of a localized fibrous tumor of the pleura for having been diagnosed in a patient under 40 years old, with an infrequent symptomatology and because the tumor has shown a benign behavior even with cystic features.


Subject(s)
Humans , Pleural Neoplasms/diagnosis , Solitary Fibrous Tumor, Pleural/etiology
11.
Gac. méd. espirit ; 15(3): 331-337, sep.-dic. 2013.
Article in Spanish | LILACS | ID: lil-696672

ABSTRACT

Introducción: la evaluación de un paciente con exacerbación de asma bronquial incluye la búsqueda de enfermedades que pueden simular, complicar o perpetuar esa situación. El dolor retrosternal es un síntoma atípico en pacientes con exacerbación asmática y entre las causas que lo pueden originar están las masas mediastínicas como el timoma. Un tercio de los pacientes con timomas pueden tener síntomas asociados a enfermedades autoinmunes y síndromes paraneoplásicos; sin embargo, aunque el asma bronquial tiene un componente inmunológico importante en su fisiopatología, la asociación del timoma con el asma está poco documentada. Objetivo: ofrecer una enseñanza clínica a través de la presentación de un caso con asociación inusual de timoma y asma bronquial. Presentación del caso: se presenta el caso de una paciente de 50 años que acudió a servicios de urgencias con exacerbación asmática y dolor torácico retrosternal. En tomografía computarizada de alta resolución se observó una masa en mediastino anterosuperior que tras realizar exéresis quirúrgica y estudios inmunohistoquímicos fue diagnosticada como un timoma epitelial tipo IIB. Conclusiones: la presencia de síntomas inusuales en una paciente con exacerbación asmática condujo al diagnóstico de un timoma epitelial, aun cuando no se ha demostrado la asociación entre estas dos enfermedades.


Background: the evaluation of a patient with bronchial asthma exacerbation includes the search for diseases which can simulate, complicate or perpetuate that situation. The retrosternal pain is an atypical symptom in patients with asthmatic exacerbation and among the causes that can originate this symptom are mediastinal masses like thymoma. A third part of patients with thymomas might have symptoms associated with autoimmune diseases and paraneoplastic syndromes; however, although asthma has an important immunologic component in its pathophysiology, association of thymoma with asthma is poorly documented. Objective: to offer a clinical lesson through a presentation of a case with unusual association of thymoma and asthma. Case presentation: a 50 year-old female patient with asthmatic exacerbation and retrosternal thoracic pain came to emergency services. A mass in anterosuperior mediastinum was observed in computed tomographic high-resolution scan and after performing surgical exeresis and immune histochemistry studies an epithelial timoma type IIB was diagnosed. Conclusions: the presence of unusual symptoms in a patient with asthma exacerbation led to an epithelial thymoma, even when there has not been shown association between these two diseases.


Subject(s)
Humans , Chest Pain/complications , Mediastinal Neoplasms/diagnostic imaging , Asthma/complications
12.
Saúde Soc ; 22(3): 727-735, jul.-set. 2013. tab
Article in Spanish | LILACS, SES-SP | ID: lil-694146

ABSTRACT

OBJETIVO: el objetivo de este estudio consistió en analizar si existen diferencias en la gestión preventiva llevada a cabo en varias empresas que presentaron enfermedades profesionales en función del género de los trabajadores. MÉTODOS: se analizó una muestra de 302 trabajadores, siendo el 31,1 por cento mujeres, de empresas donde se había declarado enfermedad profesional en la provincia de Valencia (España). Los datos se recogieron mediante un cuestionario con 40 preguntas. RESULTADOS: los resultados indicaron que en estas empresas se realizaba una gestión preventiva en la que el plan de prevención y la participación de los trabajadores eran las actividades que con menor frecuencia se aplicaban, y en el caso de las mujeres la gestión preventiva llevada a cabo resultaba significativamente peor que para los hombres. CONCLUSIONES: se concluye que con referencia a la prevención de riesgos laborales el género puede ser una variable que genera una discriminación negativa hacia las mujeres trabajadoras. Además, los riesgos laborales y los problemas de salud asociados deberían ser considerados un problema de salud pública.


PURPOSE: this study analyzed the differences in preventive management performed in companies that had informed their workers about occupational diseases, and analyzed these differences according to workers' sex.METHODS: the sample comprised 302 workers (31.1% were women). Data were collected via a 40-question survey administered in companies from the province of Valencia (Spain).RESULTS: the results showed that both prevention plans and workers' participation in designing prevention of occupational risks were activities that were less frequently developed. Moreover, with regard to workers' sex, preventive management for women was significantly worse than for men.CONCLUSIONS: in the activities of risk prevention at work, gender bias can result in negative discrimination toward female workers. In addition, occupational risks and their consequences on occupational health should be considered a matter of public health.


Subject(s)
Humans , Male , Female , Working Conditions , Gender and Health , Occupational Risks , Occupational Health , Occupational Health Services , Sampling Studies , Data Interpretation, Statistical
13.
Av. cardiol ; 31(1): 58-62, mar. 2011. ilus
Article in Spanish | LILACS | ID: lil-607766

ABSTRACT

La taquicardia ventricular incesante es una patología poco frecuente que habitualmente se presenta en pacientes con cardiopatía estructural, principalmente en aquellos con antecedentes de infarto al miocardio, sin embargo puede presentarse también en enfermos con miocardiopatía dilatada. La amiodarona puede controlar con éxito un 75% de los casos y en aquellos pacientes refractarios al tratamiento antiarrítmico la ablación por radiofrecuencia debe considerarse la terapia de primera elección.


Incessant ventricular tachycardia is a rare disorder that usually occurs in patients with structural heart disease, mainly in those with history of myocardial infarction, but may also occur in patients with dilated cardiomyopathy. Amiodarone can successfully treat 75% cases and in patients refractory to antiarrhythmic therapy, radiofrequency ablation should be considered first-line therapy.


Subject(s)
Humans , Female , Aged , Catheter Ablation/methods , Cardiomyopathy, Dilated/diagnosis , Tachycardia, Ventricular/pathology , Cardiology
14.
Av. cardiol ; 30(4): 408-411, dic. 2010. ilus, graf
Article in Spanish | LILACS | ID: lil-607785

ABSTRACT

Se presenta el caso de un paciente que ingresa a nuestro servicio presentando terapias inapropiadas e infección del bolsillo, posterior al implante de un desfibrilador automático implantable con un electrodo Sprint Fidelis 6949 en estado de alerta del fabricante...


A case of a patient who was admitted to our department with inappropriate therapies and infection of the pocket, after implantation of an implantable defibrillator with a Sprint Fidelis 6949 electrode on alert of the manufacturer...


Subject(s)
Humans , Male , Aged , Defibrillators, Implantable/adverse effects , Cardiovascular Infections/complications , Cardiovascular Infections/etiology , Postoperative Complications , Thoracic Surgery
15.
Mem. Inst. Oswaldo Cruz ; 105(6): 823-828, Sept. 2010. ilus, tab
Article in English | LILACS | ID: lil-560670

ABSTRACT

We present filaria-nested polymerase chain reaction (PCR), which is based on amplification of first internal transcribed spacer rDNA to distinguish three parasitic filarial species (Onchocerca volvulus, Mansonella ozzardiand Mansonella perstans) that can be found in the Amazon Region. Nested PCR-based identifications yielded the same results as those utilizing morphological characters. Nested PCR is highly sensitive and specific and it detects low-level infections in both humans and vectors. No cross-amplifications were observed with various other blood parasites and no false-positive results were obtained with the nested PCR. The method works efficiently with whole-blood, blood-spot and skin biopsy samples. Our method may thus be suitable for assessing the efficacy of filaria control programmes in Amazonia by recording parasite infections in both the human host and the vector. By specifically differentiating the major sympatric species of filaria, this technique could also enhance epidemiological research in the region.


Subject(s)
Animals , Humans , DNA, Protozoan , DNA, Ribosomal , Mansonella , Onchocerca volvulus , Polymerase Chain Reaction , Brazil , Mansonella , Mansonella , Onchocerca volvulus , Reproducibility of Results , Species Specificity
17.
Salud ment ; 30(2): 19-24, mar.-abr. 2007.
Article in English | LILACS | ID: biblio-986003

ABSTRACT

Summary Introduction: Systemic lupus erythematosus (SLE), a prototype of the autoimmune diseases, is a multi-systemic disease characterized by an alteration in the immunological response, where the production of antibodies is directed against nuclear antigens, thus affecting many organs and systems. The course of this disease includes a wide range of clinical manifestations, different anatomo-pathological findings, and a series of immunological abnormalities. It is characterized by outbreaks and remissions. SLE can be manifested by general malaise, fever, fatigue, weight loss, skin rashes or joint inflammation, anemia, inflammation of the lymphatic glands, lowering of the defenses against infection, and cardiac, kidney, pulmonary and neurological alterations. In chronic dermatological lupus, only the skin is affected; this condition can present rash erythemas, etc. The recent introduction of new immunological diagnostic methods (antinuclear antibodies, anti-DNA antibodies, complementary fraction, etc.) has made it possible to recognize less severe forms of the disease, as well as its outbreaks and therapeutic guidelines. Different psychological variables have been associated with the exacerbation of the disease; one of the most notable is stress, and many patients with lupus also suffer diverse psychiatric and personality disorders associated with the disease, with a prevalence oscillating between 20% and 60%. Furthermore, these alterations have been associated with a lower quality of life, poorer evolution and psychiatric antecedents. In the specific case of personality alterations, previous research has found the existence of a "triad of personality" characteristics in patients with lupus. Depression, hysteria and hypochondria are the factors making up this triad. However, it has not been shown whether these personality disorders are just another symptom of the disease or a consequence of the emotional disorders produced by it. The purpose of this study was to test the possible existence of personality disorders and their relationship with other affective disorders in SLE. Methods: In order to do this, we studied 30 patients with lupus and evaluated their possible personality disorders with the MMPI and their levels of depression and anxiety with the BDI and STAI, respectively. Then, after analyzing the results obtained on the tests administered, three groups were established: patients with lupus who had no emotional disorders, patients with lupus who presented clinical anxiety, and patients with lupus who presented clinical depression. These categories were represented graphically. In order to test the effects of anxiety and depression in the psychopathological personality profile, 10 between-group univariate variance analyses (ANOVA) were carried out, one for each subscale of the MMPI. The variable "presence or non-presence of emotional disorders" was the two-level factor. Results: In the graphic representation of the personality patterns of the three groups, it can be seen that patients with lupus who did not present emotional disorders (neither depression or anxiety) did not show any alterations in their personality patterns. However, this pattern was altered in those who presented depression or anxiety. Later, the results found show statistically significant differences on the subscales of Hypochondria [F=9.795, df=1, 29, ±0.004)], Psychasthenia [F=15.266, df=1, 29, p±0.001], and Schizophrenia [F=4.97, df=1, 29, p±0.001)] among those patients who presented emotional disorders and those who did not present any emotional disorder, with the latter receiving higher scores. Conclusion: We can state that the development of personality disorders in patients with lupus is associated with emotional alterations, which probably relate more to processes of adaptation to the disease than to the disease itself.


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18.
Rev. bras. ginecol. obstet ; 28(12): 728-732, dez. 2006.
Article in Portuguese | LILACS | ID: lil-445904

ABSTRACT

A biópsia do linfonodo sentinela no tratamento do câncer de mama vem substituindo a linfadenectomia em casos iniciais. Este tratamento pode ser realizado com o corante azul vital e/ou radiofármaco. Há relatos de reações alérgicas ao corante com diferentes graus de severidade. Relata-se um caso de reação anafilática severa após injeção intradérmica do corante azul patente, em paciente com diagnóstico de carcinoma ductal in situ. O corante azul patente, apesar de facilitar a detecção do linfonodo, apresenta risco de desencadear reações anafilactóides. É necessário que a equipe envolvida tenha preparo para diagnosticar e tratar esta complicação.


Sentinel lymph node biopsy in the treatment of breast cancer has been replacing lymph node resection in early cases. This treatment may be performed with blue dye and/or radiopharmaceuticals. There are reports of allergic reactions to blue dye with different degrees of severity. A case of severe anaphylactic reaction after intradermal injection of patent blue dye was reported in a patient diagnosed with ductal carcinoma in situ. The patent blue dye facilitates the detection of the sentinel lymph node, but there is the risk of triggering anaphylactic reactions. It is recommended the team involved to be very knowledgeable and prepared to diganose and treat this complication.


Subject(s)
Humans , Female , Middle Aged , Coloring Agents/adverse effects , Anaphylaxis/chemically induced , Breast Neoplasms , Sentinel Lymph Node Biopsy/adverse effects , Carcinoma, Intraductal, Noninfiltrating/surgery , Hypersensitivity
19.
Rev. cuba. med. mil ; 34(1)ene.-mar. 2005. ilus
Article in Spanish | LILACS | ID: lil-403376

ABSTRACT

La deformidad de Klippel-Feil es una anomalía del desarrollo que afecta comúnmente a las vértebras cervicales. La entidad se asocia por lo general con otras deformidades con anomalías o sin ellas tanto del sistema nervioso como de otros sistemas de órganos. Se reporta un paciente adulto de 35 años de edad que sin antecedentes familiares o personales de enfermedades causantes de deformidades con anomalías óseas o sin ella se le diagnóstica la enfermedad de Klippel-Feil, con anomalías neurales en la resonancia magnética nuclear. Clínicamente presentaba síntomas y signos propios de la compresión medulocerebeloso por lo que se le realiza una craniectomía de fosa posterior con laminectomía de C1 y duroplastia. La evolución es satisfactoria con la desaparición de la mayoría de los síntomas


Subject(s)
Humans , Male , Adult , Arnold-Chiari Malformation , Klippel-Feil Syndrome/surgery , Klippel-Feil Syndrome/classification , Klippel-Feil Syndrome/diagnosis , Syringomyelia
20.
Rev. cuba. med. mil ; 33(1)ene.-mar. 2004. ilus
Article in Spanish | LILACS | ID: lil-387073

ABSTRACT

Los ependimomas medulares tienen una localización generalmente intradural intramedular, y de ellos el 90 por ciento se originan del filium terminal, cono medular y cauda equina. Se reporta una paciente de 54 años de edad a quien se le practicó una mielografía por aquejar dolor radicular, hipoestesia en silla de montar y debilidad de la extremidad inferior derecha; se demostró una lesión ocupativa en región de la cola de caballo. Se practicó una laminectomía exponiendo una tumoración bien definida, encapsulada y que no comprometía raíz, filium ni cono medular. Se resecó la lesión con el empleo de técnicas microquirúrgicas. El diagnóstico patológico reportado fue ependimoma. Según la literatura revisada solo se han publicado 11 casos de ependimomas primarios de localización intradural extramedular


Subject(s)
Humans , Female , Middle Aged , Central Nervous System Neoplasms , Ependymoma , Laminectomy , Neurosurgical Procedures , Spinal Cord Neoplasms
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