ABSTRACT
The purpose of this study was to compare the cariogenic potential of a typical cassava flour (CF) with sucrose and starch, using a severe cariogenic challenge model in rats. Thirty Wistar female pups with their dams (mutans streptococci free) were infected by Streptococcus sobrinus 6715, desalivated when aged 25 days, and placed in a Konig-Hofer programmed feeder at age 26 days. They received 17 meals daily at hourly intervals for 21 days as follows: group (1) powdered plain sucrose and sterile distilled water ad libitum (sdwal); (2) Lf and Sdwal (3) powdered starch and sdwal. Essential nutrition was administered by gavage. Data were analyzed by ANOVA. The percentage of S. Sobrinus related to the total flora and the number of this microorganism were higher in the sucrose and CF groups than starch group. Smooth-surface and [sulcal] caries scores for the groups were: (1) 105.5 [48.0]; (2) 34.1 [39.2]; (3) 10.2 [18.1]. All the groups were statistically significantly different from each other (p < 0.01), although the result for sulcal score for CF was very close to the sucrose group. It is concluded that cassava flour, the main source of carbohydrate for the Amazonian population of Brazil, has moderate cariogenic potential.