ABSTRACT
Objective To explore clinical efficacy of Shenlingbaizhu decoction on immune status in patients with ulcerative colitis(UC).Methods 60 patients with UC were selected and divided into control group and experiment group evenly and randomly.Control group received treatment of salazosulfapyridine,while experiment group received treatment of Shenlingbaizhu decoction based on treatments of control group.Clinical efficacy,serum levels of IL-6 and IL-8,percentage of Treg cells in peripheral blood were observed and compared between two groups before and after treatments.Results Total clinical efficacy of experiment group was significantly higher than that of control group(P＜0.05)(90.00％ vs 76.67％);Serum level of IL-6 was decreased significantly in all patients(P＜0.05),more significantly in experiment group(P＜0.05)after treatment;Serum level of IL-10 increased significantly in experiment group after treatment(P＜0.05);Percentage of Treg cells increased significantly in experiment group after treatment(P＜0.05).Conclusion Combination therapy of salazosulfapyridine and Shenlingbaizhu decoction shows significantly better clinical effects than salazosulfapyridine alone,probably via regulating immune status.
ABSTRACT
Objective To observe the efficacy of omidazole in the treatment of trichomonal vaginitis.Methods 64 cases with trichomonal vaginitis were divided into two groups randomly.The experiment group(32 cases) was given ornidazole,while the control group was given metronidazole.Changes in symptoms laboratory tests,vaginal examination and adverse reactions were compared between the two groups.Results The efficacy of experiment group was significantly better than the control group( P ＜ 0.05).The experiment group's adverse reactions were sigenificantly less than the control group ( P ＜ 0.05 ).Conclusiou Ornidazole used in the treatment of trichormonal vaginitis shows a significant effect with long duration and less adverse reactions,so it's should be promoted.