ABSTRACT
Rational drug-use is an extremely important component part in morden medical and health work. And irrational drug-use will aggravate drug misadventure, increase overpreseribing, waste medicinal resources and harm the reputation of medical workers. The tendency of polypharmacy just for more hospital income, regardless of drug-related adverse effects, comes to be a serious problem and hard to control in recent years. No perfect management system and lack of information may be the major factors of the problem. In order to overcome the irrational drug-use characterized by polypharmacy, we should learn something from the Diagnosis Related Groups/Prepayment System (DRGS/PPS). Now, under the cooperation of The Chinese Pharmacological Society ,The Chinese Pharmaceutical Association and The Public Health Ministry of PLA, a Diagnosis Related Rational Drug-use Management System and a Computerized/Telecommunication Based Dynamic Knowledge Bank are able to be developed. We consider that it will contribute to the modernization of medical and health work in China in the near future.