Pharmacological study of aqueous extract of Scoparia dulcis L. on gastrointestinal tract

The research study was conducted in an attempt to analyze the relative pharmacological effect of the aqueous extracts of Scoparia dulcis L. on the gastrointestinal tract. The Gastrointestinal Motility [GI-Motility] test, Castor oil and MgS0[4] induced diarrhoeal tests were performed utilizing laboratory mice. Scoparia dulcis L. showed laxative effect as revealed by the GI-Motility test, the Castor oil induced and MgSO[4] induced diarrhoeal tests

Effect of vasantakusumakar rasa: an ayurvedic antidiabetic drug on central nervous system and gastrointestinal tract

The present study was carried out to investigate some pharmacological effects of Vasantakusumakar Rasa [VKR] on the Central Nervous System [CNS] and the Gastrointestinal [GI] Tract utilizing laboratory mice. The CNS study comprised of Hole cross test, Open field test and Hole board test and the GI study comprised of GI-Motility, Castor oil induced and MgSO[4] induced diarrhoeal tests. VKR showed stimulatory effect in the Hole cross test, Open field test and the Hole board head dipping test. In case of GI-Motility test, VKR decreased the gut movement. In case of Castor oil induced diarrhoeal test the mean latent period increased. There was no prominent effect in MgSO[4] induced diarrhoeal tests. Conclusion from the above tests reveals that VKR has CNS stimulant activity and constipatory effect on the Gastrointestinal Tract