ABSTRACT
Objective To evaluate the value of transvaginal three -dimensional ultrasound(3D -TVS)in the diagnosis of uterine cavity lesions.Methods 100 patients with suspected uterine cavity lesions,firstly underwent transvaginal ultrasound examination,then underwent transvaginal three -dimensional ultrasonography,and the trans-vaginal ultrasound and transvaginal three -dimensional ultrasound examination was judged by hysteroscopy standard. The diagnostic methods and hysteroscopy examination results of the two groups were compared and analyzed,and the three -dimensional ultrasound imaging data were analyzed.Results The ultrasound findings of transvaginal two -dimensional showed that there were 91 cases in line with hysteroscopy(lesion 142),the accuracy was 64.54%,the differences were statistically significant(χ2 =4.872,4.913,8.198,13.254,10.137,all P <0.05).At the same time, the three -dimensional ultrasound examination results of vaginal showed consistent with hysteroscopy 132,the accuracy was 93.62%,the differences were statistically significant(χ2 =2.872,7.387,10.258,18.275,12.259,all P <0.05).Transvaginal three dimensional ultrasound examination of common uterine cavity lesions ultrasound image was clear,and the size,shape and location of the lesion were clearly visible.Conclusion Three dimensional ultra-sound in the diagnosis of uterine cavity lesions has high accuracy,its image data is more clear,and in the clinical diagnosis of uterine cavity lesions has high value of application,and it is worth of promoting.
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In total, 607 bedridden patients aged 60 years and over at Tianlin community hospital and four other hospitals or at home-care in Shanghai were investigated with questionnaire, physical examinations and related laboratory tests. Contents of investigation include general situation, medical conditions, 24-hour recall of diet, intake of nutritional supplement preparation, and so on. As compare to the reference for nutrient intake of the elderly set in the Guide to Diet for Chinese Residents (2007), total nutritional intake was obviously insufficient and three nutrients in diet were imbalanced for most bedridden elderly patients. Intake of most nutrients (including proteins, dietary fiber, calcium, iron, zinc, selenium,copper, magnesium, phosphor, retinol equivalent, vitamin B1 , vitamin B2, vitamin C) was obviously low in bedridden elderly patients, with a larger gap from the requirements of the Dietary Guide.
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To study the immunoregulatory effect of an optimal Chinese herbal monomer compound, which consists of three monomers, namely, icariin, baicalin and Astragalus saponin I, in a mouse model of allergic rhinitis.
ABSTRACT
Objective: To study the optimal combined ratio of baicalin, icariin and Astragalus saponin I from a Chinese herbal compound Biminne. Methods: Firstly, a mouse model of allergic rhinitis was established by intraperitoneal injection of ovalbumin (OVA) and aluminum hydroxide gel suspension, and the effective dose range of baicalin, icariin and Astragalus saponin I was detected by 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt method. Secondly, 10 groups of combinations of baicalin, icariin and Astragalus saponin I assembled by U*(10)(10(8)) form were employed to determine the optimal combination by means of analyzing of the inhibitory effect on the splenocyte proliferation. Finally, the effects of each effective ingredient and the optimal combination were compared by observing the splenocyte proliferation, the contents of interleukin-4 (IL-4), IL-5, interferon-gamma (IFN-gamma) in supernatant of the splenocyte cultures and the ratio of IL-4 to IFN-gamma in order to verify the result. Results: Baicalin or icariin at concentrations ranging from 2 to 10 mumol/L, and Astragalus saponin I from 1 to 10 mumol/L effectively suppressed the splenocyte proliferation. When the proportion of baicalin, icariin and Astragalus saponin I was 1:2.14:2.65, the inhibitory effect was most remarkable. Further research confirmed the rationality of the optimal combination. Conclusion: An optimal combination of the major effective ingredients from Chinese herbal compound Biminne most effectively suppresses the proliferation of splenocytes from sensitized mice and regulates the cytokine secreting.