ABSTRACT
OBJECTIVE:To evaluate the status quo and the rationality of the drug utilization in patients with chronic hepatitis B in our hospital.METHODS:The methods of drug utilization review (DUR) and drug utilization evaluation (DUE) were used to comprehensively analyze the drug utilization,diagnosis,monitoring of therapeutic process as well as therapeutic outcome of 78 patients with chronic hepatitis B hospitalized in our hospital from April 2007 to April 2008.RESULTS:Of the 78 cases reviewed,2 were treated with 1 kind of drug,and 76 with at least 2 kinds of drugs in combination;pathological staging was performed for only 6 cases,all of the 78 underwent therapeutic monitoring during therapeutic process.The DUIs of 11 kinds of drugs were more than 1,DUI
ABSTRACT
OBJECTIVE:To study the status and characteristics of the adverse drug reactions(ADR) presented in our hospital.METHODS:A total of 393 ADR cases collected during the period 2003～2007 in our hospital were analyzed statistically regarding the general status of the patients,route of administration,drug variety,the types of lesions and the clinical manifestations etc.RESULTS:Of the 393 ADR cases,the aged people(≥61 a) showed a highest incidence at 21.88%, 83.71%were induced by intravenous infusion,72.26%were induced by anti- infective drugs,lesions of skin and the appendants were the major type of ADR,accounting for 39.94%,and there were only 36 serious eases,accounting for 9.16%. CONCLUSION:ADR reporting and monitoring should be strengthened in hospital.Making full use of hospital ADR infor mation can facilitate rational drug use and improve clinical rational drug use level.