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Objective:To explore the hemodynamic changes in aged patients with essential hypertension (EH). Methods: Our research included 2 groups, EH group, n=180 patients and Control group, n=100 subjects without cardiovascular diseases. The relevant indexes were recorded and compared by BioZ.com noninvasive hemodynamic monitor between 2 groups. Results: With statistic processing, the cardiac output/index (CO/CI), cardiac index, thoracic lfuid content (TFC), systemic vascular resistance/index (SVR/SVRI) were signiifcantly different between EH group and Control group, all P Conclusion: The hemodynamic changes exist at certain degree indicating the potential injury of cardiac function in aged EH patients, such changes might be helpful for clinical diagnosis and treatment in EH patients.
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OBJECTIVE@#To evaluate correlation between and agreement in light transmittance aggregation (LTA) and thromboelastography (TEG) in laboratory diagnosing aspirin resistance (AR), and to determine the prevalence of AR in old patients.@*METHODS@#Patients in the Wanshoulu District of Beijing with ischemic atherothrombotic diseases were recruited. Inclusion criteria were age ≥ 65 years, and having received regular aspirin therapy (75-100 mg daily) for at least 4 weeks. On the basis of LTA assay, the definition of AR was taken as aggregation of ≥ 20% with AA (arachidonic acid), and of ≥ 70% with ADP (adenosine diphosphate). Aspirin-sensitivity was indicated by the absence of either of these criteria; aspirinsensitivity was indicated as both criteria being met. The definition of AR by TEG is ≥ 50% via AA-induced whole blood aggregation.@*RESULTS@#There were 13.69% prevalence of aspirin resistance for LTA using AA as the agonist, 30.16% prevalence of aspirin resistance for LTA using ADP as the agonist, and 23.67% prevalence of aspirin resistance for TEG using AA as the agonist. Results from these tests showed poor agreement (Kappa<0.4). However, by the method of LTA using AA and ADP as the agonists, prevalence of AR was 8.35%. By methods of AA-induced LTA and AA-induced TEG, prevalence of AR was 8.82%. Results from these two latter methods showed good agreement (Kappa = 0.793).@*CONCLUSION@#Combined methods, as described here, have good correlation and agreement in the assays of AR, and the results with them represent a realistic measure of the prevalence of AR. Prevalence of AR of elderly patients from Wanshoulu district of Beijing is about 9%.
Subject(s)
Aged , Female , Humans , Male , Aspirin , Pharmacology , Therapeutic Uses , Cerebrovascular Disorders , Blood , Drug Therapy , Coronary Disease , Blood , Drug Therapy , Drug Resistance , Platelet Aggregation , Platelet Aggregation Inhibitors , Pharmacology , Therapeutic Uses , Prevalence , Surveys and QuestionnairesABSTRACT
Objective To analyze causative factors and treatment of acute lung injury (ALI) after liver transplantation. Methods the correlative parameters, including electrocardiogram, blood oxygen saturation, blood pressure, hemodynamics, blood sugar, analysis of arterial blood gases, and other clinical examinations were monitored dynamically. The recipients were treated with oxygen inhalation, antibiotics, immunosuppressant, drugs for liver protection, nutritional support, diuretics, and vasodilators. Results Three of a total of 21 patients died within 48h post operation. Fourteen patients suffered from ALI (14/18, 77 8%), who recoverd after receiving appropriate treatment. Conclusion The occurrence of ALI is related to the primary disease, operative trauma, instability of the hemodynamics, and the quantity of blood loss. Systemic treatment is necessary for the patients with ALI besides the oxygen therapy.
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Objective To investigate the levels of blood sugar and electrolyte in nonage of 125 patients with liver transplantation.Methods According to the parameters of blood sugar and electrolytes,the usage of insulin and electrolyte was adjusted whenever necessary.The levels of blood sugar and electrolytes were maintained respectively in 6～10 mmol/L and normal limits.The oxygen inhalation,antibiotics,immunosuppressant,liver protectant,diuretics and vasodilators were also used in the preoperative period.Results Of 125 cases of liver transplantation recipients,there were 50(40%) cases with blood sugar heightened remarkably.Massive potassium chloride and sodium chloride was used to keep electrolytes in normal limits.Conclusion The levels of blood sugar and electrolytes are not stable in nonage of liver transplantation and it is very important to maintain them in normal limits for the success of liver transplantation.