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Rev. cuba. invest. bioméd ; 39(4): e604, oct.-dic. 2020. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1156461

ABSTRACT

La insuficiencia cardiaca se define como un síndrome caracterizado por la incapacidad de proveer las necesidades metabólicas del organismo, presentando disnea y fatiga. Hasta ahora, se ha descrito la participación de varias moléculas involucradas en los mecanismos de señalización intracelular que conducen a la insuficiencia cardiaca y estimulan la síntesis de algunas proteínas, como colágeno, la cual induce a una hipertrofia cardiaca(AU)


Heart failure is defined as a syndrome characterized by the inability to meet the metabolic needs of the organism, causing dyspnea and fatigue.Descriptions are available of the involvement of several molecules in cell signaling mechanisms which lead to heart failure and prompt the synthesis of some proteins, such as collagen, inducing cardiac hypertrophy(AU)


Subject(s)
Humans , Heart Failure/genetics , Molecular Biology , Angiotensins/therapeutic use , Signal Transduction/genetics , Cardiomegaly/complications
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