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1.
Rev. am. med. respir ; 11(1): 18-23, mar. 2011. tab, graf
Article in Spanish | LILACS | ID: lil-648913

ABSTRACT

No existe evidencia sobre la limitación por síntomas al ejercicio comparando pruebas máximas y submáximas en pacientes con EPOC. Objetivos: Comparar la referencia de limitación por disnea o fatiga entre una prueba de ejercicio máxima y submáxima. Métodos: Se incluyeron pacientes con EPOC moderada y severa (definición GOLD). Se clasificó como limitados por fatiga (LF) si en cicloergometría máxima tenían una diferencia = 2 puntos en la escala de Borg para fatiga de miembros inferiores vs. disnea. Se los clasificó como limitados por disnea (LD) por lo inverso. Se les realizó pruebas ergométricas submáximas, evaluándolos igual. Resultados: Se evaluaron 15 pacientes LD y 18 LF. En pacientes LF predominaban mujeres (LF 55.5 vs LD 26.6% p: 0.034), tenían menor índice peso/talla (LF 24.1 ± 3.2 vs. LD 26.8 ± 2.1; p<0.04) y menor obstrucción al flujo aéreo (LF 47 ± 13.8% vs. LD 34.5 ± 11.1%, p<0.047). En pacientes con LF, las pruebas máximas y submáximas fueron concordantes (Borg 2.8 ± 2; 2.5 ± 2.2, p=NS), pero no en aquéllos con LD (Borg 5.7 ± 2.1; 3.3 ± 1.6, p=0.014). Las pruebas submáximas son específicas (100%: fatiga y 93.3%: disnea) y tienen pobre sensibilidad (44%: fatiga y 35.7%: disnea) para clasificar a los pacientes en la causa de limitación. Conclusión: Los pacientes con LF presentan menor grado de obstrucción bronquial e índice peso-talla. En pacientes LF las pruebas máximas y submáximas fueron concordantes. Las pruebas submáximas son específicas pero tienen poca sensibilidad para clasificar por causa de limitación por síntomas.


There are no data about symptoms of activity limitation in COPD patients when maximal and submaximal exercise tests are compared. Objective: To compare the activity limitation by dyspnea or fatigue between maximal and submaximal exercise tests. Methods: Moderate and severe COPD patients were included (GOLD definition). They were classified as fatigue limited (FL) if Borg scale of fatigue at maximal exercise was = 2 points vs. dyspnea; and dyspnea limited (DL) if it was the reverse. Each patient was evaluated in the same way with submaximal cycloergometry. Results: 15 patients in the LD group and 18 patients in the LF group were evaluated. The LF patients were mainly women (FL 55.5 vs. DL 26.6% p: 0.034), had a low body-mass index (FL 24.1 ± 3.2 vs. DL 26.8 ± 2.1; p<0.04) and less airway obstruction (FL 47 ± 13.8% vs. DL 34.5 ± 11.1%, p<0.047). Maximal and submaximal tests were concordant in FL patients (Borg 2.8 ± 2; 2.5 ± 2.2, p=NS), but not in DL patients (Borg 5.7 ± 2.1; 3.3 ± 1.6, p=0.014). Conclusions: FL COPD patients had less airway obstruction and body-mass index. In FL patients both tests were concordant. The submaximal exercise tests are specific but they have low sensitivity to determine the cause of symptom limitation.


Subject(s)
Humans , Male , Adult , Female , Breath Tests , Dyspnea , Pulmonary Disease, Chronic Obstructive , Exercise Test , Exercise/physiology , Fatigue
2.
Medicina (B.Aires) ; 64(2): 113-119, 2004. tab
Article in Spanish | LILACS | ID: lil-444347

ABSTRACT

A survey on COPD diagnostic procedures, treatment and management was conducted in a group of 517 chest physicians randomized from a list of the 1121 affiliates to the Asociación Argentina de Medicina Respiratoria. One hundred eighty-seven responses were obtained (36.2% of the questionnaires mailed). They treat an average of 53.3 COPD patients every month. Twenty-four percent of them had mild, 41.8% moderate and 33.8% severe disease (GOLD criteria). Only clinical criteria for diagnosis of COPD, clinical criteria + spirometry (S), and clinical criteria + S + chest X ray were used by 2.9, 23.4 and 73.7% of responders, respectively. Seventy percent of responders believed that chronic asthma without bronchodilator response must be included in the COPD definition. Only 14.1% of responders performed S in every office visit. Cardiac function was assessed using clinical criteria, electrocardiogram and echocardiogram by 90.6, 80.6 and 73.8% of responders, respectively, while 98.3% stated that they trained most of their patients in the inhalation technique. Metered Dose Inhaled was the first option for bronchodilators administration (64.8%) followed by nebulization (16.5%), dry powder inhalation (13.7%) and oral administration (4.8%). First option for chronic therapy in severe COPD patients was the association of anticholinergic drug (AC) + short acting beta2-agonists (SABA) (65.5%), AC alone (18.8%), long acting beta2-agonists (LABA) (9.7%), inhaled corticosteroids (IC) (3.5%) and SABA alone (2.8%). Corticosteroids and antibiotics were prescribed in severe COPD exacerbation by 92.5 and 70% of responders, respectively. First choice antibiotic formulation was beta-lactamics + beta-lactamase inhibitors in 39% of the responders followed by fluorquinolones in 23.7%, macrolides in 17.5% and beta-lactamics in 12.5%. Lastly, 12.7% of COPD patients received long-term domiciliary oxygen therapy. 59.3% of them were prescribed pulmonary rehabilitation, 94.1% vaccination against in...


Se realizo una encuesta acerca de diagnostico y tratamiento de EPOC a un grupo de 517 especialistasen neumonologia, seleccionados al azar entre los 1121 integrantes de la Asociacion Argentina de Medicina Respiratoria. Se obtuvieron 187 respuestas (36.2%). Atienden en promedio 53.3 pacientes con EPOC/mes, a los cuales definen como leves el 24.2%, moderados el 41.8% y severos el 33.8% (criterios normativos GOLD).El criterio utilizado para el diagnostico de EPOC fue solo clinico en el 2.9%, clinico y espirometria (ESP) en el 23.4%y clinico, ESP y por imagenes en el 73.7%. El 70.1% de los encuestados incluye dentro de la definicion de EPOC al asma cronico de escasa respuesta a broncodilatadores. Solo el 14.1% manifiesta realizar espirometria en cada consulta. La evaluacion de la funcion cardiaca la realizan en EPOC severa por examen clinico (90.6%), electrocardiograma (80.6%) y ecocardiograma (73.8%). El 98.3% de los encuestados afirma que la mayoria de los pacientes son instruidosen la realizacion de maniobras de inhalacion de medicamentos. Eligieron como primera opcion para administrarbroncodilatadores en aerosol (64.8%), nebulizacion (16.5%), polvo (13.7%) y via oral (4.8%). El 65.5% eligio comoprimera opcion de tratamiento cronico a los anticolinergicos (AC) + beta2-agonistas de acción corta (BAAC), 18.8% ACsolos, 9.7% beta2-agonistas de accion larga (BAAL), 3.5% corticoides inhalados (CI) y 2.8% BAAC solos. Los corticoides sistemicos y los antibioticos fueron utilizados en las reagudizaciones severas por el 92.5% y el 70% de los encuestados, respectivamente. En esa situacion, como antibioticos de primera eleccion, fueron elegidos los beta lactamicos + inhibidores de beta-lactamasa por el 39.1% de los encuestados, fluorquinolonas (23.7%), macrolidos (17.4%) y betalactamicos...


Subject(s)
Humans , Clinical Competence/standards , Pulmonary Disease, Chronic Obstructive , Pulmonary Medicine , Professional Practice/standards , Argentina , Practice Patterns, Physicians' , Practice Guidelines as Topic , Pulmonary Disease, Chronic Obstructive/diagnosis , Pulmonary Disease, Chronic Obstructive/therapy , Health Care Surveys , Surveys and Questionnaires
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