ABSTRACT
It is important that dentists recognize the potential of regenerative endodontics in the treatment of necrotic, immature teeth. Revascularization is a paradigm shift in the treatment of immature, necrotic teeth has occurred with biologically-based principles and regenerative endodontic protocols replacing traditional 'apexification'procedures. Preliminary research suggests that stem and progenitor cells from the pulp and/or periodontium contribute to continued root development when regenerative procedures are followed. Two case reports are included, in which different types of intra canal medicaments were used in immature permanent teeth disinfection. Both cases equally lead to successful results. Continued root development, apical closure and elimination ofperiapical radiolucency were evident