ABSTRACT
Introduction: The aim of current study was to compare on the effects of regular aerobic training intensities on PGC1-alpha- dependent myokine serum changes and to evaluate lipid profile changes in sedentary obese men
Materials and Methods: Thirty-nine obese men with BMI > 27 were selected and were divided into three groups; group I carried out exercise training with 50-60% of maximum heart rate [Low intensity], group II with 70-80% of maximum heart rate [High intensity], and group III do not carried out exercise training [control group]. All training groups carried out exercise training for 30 continuous sessions [3 sessions/per-week for 30 to 45 min per session]. After initial assessments anthropometrical, VO2max and blood sampling], followed by 10 weeks of exercise training, post-intervention assessments were completed 24 hours after the last training session
Results: Findings were clarified that Irisin was significantly increased in the low intensity group [p=0.005], and increased by twenty-seven percent in high intensity group, difference however not statistically significant [p=0.08]. Also, HDL-cholesterol significantly increased significantly in both groups [p<0.05], LDL to HDL-cholesterol ratio decreased significantly [p<0.05]. In addition, there were significant relationships between some of the lipid and anthropometrical indices with Irisin [p<0.05]
Conclusion: Both of the training interventions had a good effect on of Irisin changes and improvement of lipid profiles in obese subjects. Nevertheless, compared to other intensities, the effectiveness of low intensity training in these subjects was better. In addition, it seems that exercise training can ameliorate Irisin resistance
ABSTRACT
Effects of Phenotypic changes in adipose tissue due to training are a new theory. However, the cellular - molecular mechanisms for these phenotypic changes are not yet clearly understood. The purpose of the study was to determine the effect of high intensity interval training [HIIT] and Pilates on levels of Irisin and Insulin resistance in overweight women. This study was a Quasi-experimental research with a pre-post testing. Twenty-one overweight women, aged >/= 29.55 years were divided into two groups: High intensity interval training [N=12] and Pilates [N=9] groups. The first group performed one session of Vo2max testing for 30 s [15 s the with 120% of maximum aerobic speed and 15 s rest], while second group performed one session of Pilates. Following the second blood sampling, data analysis was performed with p values<0.05 considered significant. Results of this study show that Irisin levels increased significantly after exercise only in the HIIT group [P=0.039, t11= 2.3]. Immediately after exercise insulin resistance increased and decreased respectively in the HIIT and Pilates groups, but changes were not statistically significant [P>0.05]. Based on the findings, levels of Irisin increase in overweight women, whereas those of insulin resistance do not
Subject(s)
Humans , Female , Exercise Movement Techniques , Fibronectins , Insulin ResistanceABSTRACT
The aim of this study was compare the effects of fasting during Ramadan [as a dietary pattern] and regular aerobic exercise on HSP70, lipid profile and insulin resistance indexes in non-active obese men. In this study, 18 obese men, aged between 50-40 years, with a BMI over 30 kg/m[2] per square meter were randomly selected from among 70 volunteers responding to a public call. They were then divided into two, the fasting [N=9] and the fasting with exercise [N=9] groups. While the first group just fasted, the fasting and exercise group in addition to fasting performed 27 sessions of exercise at an intensity of 50-70% of their VO2max. Also, to study the desired changes in Ramadan, blood samples were taken at four different times points and finally, using repeated measures analysis of variance at the significance level of p<0.05, data was analyzed. Results showed that HSP70 levels in both groups increased during Ramadan. Also, HSP70 levels in both the fasting and the fasting with exercise groups increased, during the fourth week of Ramadan, the difference between the groups being significant [F=23.25; p=0.001]. Insulin resistance also decreased in both groups, a reduction that was significant in the fasting group [F=3.244; p=0.042]. Additionally, only in the fourth week of Ramadan and two weeks after that the lipid profile of the participants decreased and their HDL-C increased, changes all significant [p<0.05]. The research results show that the increased levels of HSP70 as a result of fasting perse, and fasting with exercise, may lead to decreased insulin resistance in obese men