[ prevalence of thyroid pathological lesions of in 202 autopsic samples obtained at Isfahan forensic medicine center]

Considering the influence of geographical, genetic and ethnic factors on the prevalence of thyroid pathological lesions, this study was performed to assess the prevalence of pathological lesions in thyroid autopsic samples obtained from adult cadavers of Isfahan Forensic Medical Center. In this study, 202 thyroid glands from cadavers with no evidence of thyroid diseases, removed during autopsies at Isfahan Forensic Medicine Center, were analyzed. After gross studies, thyroid glands were fixed in 5% formalin for 72 hrs, and then 3-6 sections were obtained from each gland. Tissue sections were microscopically studied by two pathologists for histopathological lesions. Among 202 thyroid glands [removed from 159 males and 43 females], 131[64.85%] were histopathologically normal, and goiter [nodular, and diffuse], Hashimoto's thyroiditis, lymphocytic thyroiditis, follicular adenoma and papillary carcinoma were observed in 41 [20.3%], 10 [4.95%], 12 [5.94%], 2 [1.49%] and 12 [5.94%] of the thyroid glands, respectively. Twenty-six glands [12.23%] had nodules sized

Study of the current parasitic contamination of the edible vegetables in Isfahan in order to identify preventive measures

Parasites infect man by way of water, soil, edible things and direct contact. Numerous factors such as the economical, social and cultural conditions as well as lack of personal health care are involved in the dissemination of the parasites. Eating of raw vegetables is common among Iranians and provides a rich source of vitamins and essential nutrients but may lead to human contamination if not washed properly. In this study 30 plant farms were selected in Isfahan in order to assess the rate of contamination of the plants. Afterwards 480 samples of the vegetables were collected and examined for cysts, eggs and larvae in Isfahan Research Center. Floatation method was used for detection of the parasite eggs. Finally the results were recorded and analyzed by means of SPSS [Version 11.5]. We found giardia cyst in 7, dicrosoelium egg in 8, hymenolepis egg in 14, ascaris egg in 16, trichostrongylus egg in 10, teania egg in 5 and trichosephalus egg in 6 cases. In fact, egg of ascaris was the most and teania was the least common parasites and fortunately we did not detect any dangerous agent like Entamoeba histolytica. In the recent years, in spite of improvement of health care, economical, social and agricultural conditions in Isfahan, parasitic infections are still prevalent. Using new methods for garbage collection, repair of ego system, preventing domestic and wild animals [like carnivorous animals] from entering into the plant farms and education of people of different social classes will be effective in reducing parasitic and infectious diseases

[ comparision of insulin level and some cardiovascular risk factors in patients with polycystic ovary syndrome and healthy subjects women]

Polycystic ovary syndrome [PCOS] seems to be the most common endocrine disease in women of reproductive age. This study has shown that PCOS is associated with hyperlipidaemia and hypertension. The aim of this study was to compare the cardiovascular risk factor in PCOS and normal women. It is a case - control study that was done on 60 barren and non-affected women and 60 barren women affected to PCOS that had clinical examples and sonographic PCOS. All of women were studied from the characteristics point of view such as age, BMI, the size of around waist and buttocks, time and kind of infertility and Blood pressure. Necessary tests were done such as total cholesterol, LDL, HDL triglyceride, insulin level and fasting blood sugar. Data were analyzed with SPSS. Triglyceride, cholesterol, LDL and BMI of the patients affected to PCOS were significantly higher than normal women [P<0.05]. HDL level reduction was significant in patients affected PCOS [P<0.05], also systolic and diastolic blood pressure in affected women was higher than control group [P<0.05]. PCOS women have higher cardiovascular risk compared to normal women

Determining anatomic thyroid indices of adult population in city of Isfahan

The aim of this study was to determine the normal anatomic indices of thyroid glands in adult population of Isfahan. In this descriptive study, 250 postmortem thyroid glands were examined. During autopsy, the thyroid glands were excised carefully and the weight and volume of glands and their lobes were measured. Then all portions were examined visually with a magnifying glass looking for gross pathologic lesions. The specimen was also examined by palpation and homogenous glands were selected for the study.The data were analyzed using SPSS software and independent T-Test and ANOVA, and divided into four distinct age groups [19-29, 30-39, 40-49 and 50-64 years old] in both sex groups. In this postmortem project, the thyroid glands of 152 men and 29 women were studied. Total mean thyroid weight and volume were 15.5 +/- 5 gr and 15.8 +/- 5 ml respectively [Table 1 and Fig. 1].Mean thyroid right lobe length, width and thickness were 4.4 +/- 0/8 cm, 2.5 +/- 0.5cm and 1.2±0.3cm respectively, the same parameters for left lobe were 4.3 +/- 0/8 cm, 2.3 +/- 0.5cm, and 1.2±0.3cm, respectively. Mean thyroid weight were higher in men comparing with women [p<0/05], except in 40-49 age group. Mean thyroid volume and weight tend to increase with age in men [p<0.05] but not in women [Table 2 and Fig. 2]. The results of our study seem to be similar with those countries in which iodine deficiency has been compensated. Because of presence of differences between the results of autopsy study and those of sonography study, these two different studies should be repeated synonymously in our country until we reach a standard basis for thyroid anatomic indexes which could be applied in next therapeutic iodine supplementary programs