ABSTRACT
Introduction: The prevalence of diabetes mellitus, a major cause of death and disability, is increasing worldwide. Considering the data available on folk medicine in Iran, this study aimed to investigate hypoglycemic and hypolipidemic effects of the aqueous extract of the plant, Thymus kotschyanus Boiss. et Hohen [Thymus. K] in patients with type II diabetes
Materials and Methods: This study is a clinical trial in which 64 patients, aged 30-60 years, with confirmed diagnosis of Type II diabetes treated with usual anti-diabetic drugs normally were randomly divided into two groups, 1. [receiving usual drugs] and 2. (Receiving Thymus. K aqueous extracts 20 gr/day with conventional therapy]. Three months later, indicators of glycemic control and lipid profiles were reassessed in both groups and compared with baseline values respectively
Results: Results showed that the groups receiving the aqueous extract Thymus. K [20 gr/day for three months] in addition to usual drugs, showed a significant decrease [p<0.05] in FBG and Hb A1C levels and a significant increase [p<0.05] in the beta cell function index [HOMA-Beta] while significantly reducing [p<0.05] is LDL-C levels
Conclusion: The aqueous extract of the plant Thymus. K in patients with type II diabetes along with the usual anti-diabetic drugs, led to better control glucose levels and also helped lower of LDL-C levels