[Primary type 1 hyperoxaluria - about two particular cases]

Primary hyperoxaluria type I is an autosomal recessive disease due to congenital defect in alanine glyoxylate aminotransferase [ACT]. It is a rare disorder in witch only combined liver-kidney transplantation is curative. Our two cases of primary type I hyperoxaluria were particular by the early renal failure, thrombocytopenia and intestinal invagination. On the basis of our two cases we discuss diagnostic and therapeutic methods

[Febrile seizures in child. A retrospective study. About 511 cases]

The aim of this study was to analyse epidemiological, clinical profile of febrile seizures, to identify indications of laboratory studies and EEG examination, and to assess risk of recurrence, and epilepsy. A retrospective study of 511 children aged from three months to five years who presented with a first febrile seizure hospitalized in the pedatrie department of Monastir Hospital from the 1[st] January 1990 to 31[th] of December 1999 was conducted. Febrile seizure represents 4, 9% of all hospitalized children between 1990 and 1999. 78% of children aged from three months to two years, sex ratio was 1, 27 with 286 boys and 225 girls. In 99, 4% of cases, febrile seizure was generalized, and tonic clonic in 82, 2%. In our study seizures [86,3%] were considered simple, although those focal onset, prolonged duration, or that occur more than once within the same febrile illenes were considered complex in 13, 7%. Recurrence was observed in 9, 9% and only 1, 2% developed epilepsy