Association between gastric helicobacter pylori infection and periodontal disease

Colonization of Helicobacter pylori [Hp] in the oral cavity may increase in the presence of the periodontal disease. It has been suggested that one of the possible mechanisms of reinfection is the recolonization from dental plaque. The purpose of this study was to determine whether periodontal disease was associated with Hp infection. Sixty-five consecutive patients [34 males and 31 females] undergoing endoscopy for investigation of dyspepsia were included in this descriptive cross-sectional study. The mean age of the patients was 41.3 +/- 13.5 years. Periodontal examination and Rapid Urease Test [RUT] were done for all of the participants. Statistical analysis was done, using Chi-square test. 53.8% of the patients had periodontal disease and 61.5% of them had gastric Hp infection. There was no statistically significant association between periodontal disease and gastric Hp infection [p=0.455]. This study revealed that the presence of periodontal disease in patients with gastric Hp infection could be and independent status

[ incidence rate of gastrointestinal tract cancers in Kerman Province during 1996-2000]

Cancer as the second leading cause of death following cardiovascular diseases has always been a threat to human life and due to its peculiar nature and lack of a favorable treatment, it is considered as a research priority in all communities. Understanding the geographical distribution of the incidence of various tumors, constitutes the first step in health and treatment planning. This study was carried out to review the incidence rate of gastrointestinal cancers in Kerman province and estimate disease load in this geographical area. Through a community-based registration system, all the documents related to cancer diagnosis in Kerman province from 1996 to 2000 were investigated. Among 5867 registered cases of cancer with an average age of 51.5 +/- 20.6 years, men composed 55.5% and women 44.5% of the cases and 1303 ones [22.2%] had gastrointestinal tract cancers among them gastric tumors [39%] had the highest incidence rate. Following gastric tumors, tumors of colon [29.4%], esophagus [12.5%], liver [5.83%] gallbladder [5.3%], and pancreas [2.84%] acquired the next ranks in regard to the incidence rate. The incidence pattern of aforementioned cancers in men showed the same pattern as the general population, but in women, colon tumors with the incidence rate of 35% have the highest incidence rate while tumors of the stomach [29.71%], esophagus [10.15%], gallbladder [9.8%], liver [5.26%] and pancreas [4.32%] were the next. Although, various GI malignancies have a lower incidence rate in Kerman province compared with other countries, the fact that these malignancies account for 22.4% of all malignancies, greatly enhances the need for serious planning for prevention, early diagnosis and correction of improper dietary habbits in this province. Moreover development of a versatile cancer registration system to evaluate the domestic comparisons seems essential

[Frequency of hepatitis B and C infection among hemophiliac patients in Kerman]

Hemophilia is the most common congenital coagulative disorder which exposes the patients to many problem because of lack of coagulative factors, higher risk of viral infections and other complications. This study was designed to detect the prevalence of hepatitis B and C infection in hemophiliac patients referring to Kerman Samenalhojaj Center. For this purpose, 97 hemophiliac patients were studied during the summer 2002 and their demographic data such as age, sex, duration of disease, history of blood transfusion and drug history were collected By means of serologic tests HBV and HCV were diagnosed In order to determine risk factors, odds Ratio was calculated From total subjects 84 were male and 13 were female and their mean age was 21.8+/-11.6 years [mean+/-SD]. Among subjects 43 person [44.3%] had HCV infection and only one person had HB V infection. Patients with HCV infection, had greater mean age comparing to the non infected patients There was statistical significant relationship between blood transfusion and HCV infection. That is, blood transfusion had increased the risk of HCV infection 2.3 times. The high risk of HCV infection in hemophiliac patients has been demonstrated in several investigations and shows the role of blood transfusion in HCV infection Lack of HBV infection in hemophiliac patients suggests that blood transfusion is not the main way of HBV infection. However, these patients are at a high risk of HBV infection. Because of many complications of HBV and HCV infection, detection of these infections in hemophiliac patients is highly necessary