Sero-prevalence of helicobacter pylori infection in congenital heart disease patient and asthmatics versus normal infants and young children

This study was conducted on 112 children with congenital heart diseases [CHD] [53 cyanotic and 59 acyanotic] attending Cairo University Children's Hospital [CUCH], cardiology outpatient clinic. They were taken over a period of 8 months. Fifty-nine asthmatics were also included, they were recruited from the chest clinic [CUCH,] during the same period. One hundred normal controls were taken from the well-baby clinic Al-Azhar University. All infants and children studied were 6 to 36 months of age. The aim of the study was to estimate the sero-prevalence of Helicobacter pylon in children with CHD and comparing them to another group of sick children like asthmatics then versus normal controls. 28.2% of the whole number of children studied [171] were sero-positive. The 100 normal controls showed 18% sero-positiveness for Helicobacter pylari. 32.1% of the cyanotic group were sero-positive compared to 18.6%of the acyanotics. Asthmatics scored 35.6%. There was a highly positive correlation between age and Helicobacter pylon infection. We concluded that Helicobacter pylon infection showed high prevalence in chronically ill children. It has to be considered as a risk for development of ulcer disease in CHD especially that these children may eventually undergo surgery, which is another risk factor for peptic ulcers. Those children may also need anticoagulation in the post-operanve period

three-year study of the defferent type of extrapulmonanary tuberculosis children

The percentage of cases diagnosed as extrapulmonary tuberculosis [EPTB] was found to be rising over the past decade. This work was done to study the different clinical forms of EPTB in children attending the chest clinic of Cairo University Children r Hospital over a period of three years 1996-1998. A total of 432 patients were diagnosed as EPTB over the study period. We then compared the data to 80 cases from the records of 1988. A significant reduction in the incidence of tuberculous [TB] lymphadenitis was noted between 1988 and 1998 [P=0. 03]. In 1988, cervical lymphadenopathy prevailed forming 77% of patients presenting with lymphadenopathy, while in 1998, the same group of lymph nodes were affected in only 55.6% [P=0.001]. Over the past years both axillaey and supraclavicular lymph node affection increased. Abdominal TB cases increased from 30% in 1988 to over 40% in the late 90's. There is an evident decrease in TB peritonitis. On the other hand combined and rare forms increased. Skeletal TB ranged from 10% to 12.5%of the cases. Central nervous system [CNS] TB presented a small percentage of patients limited to TB meningitis and tuberculomas in the cerebral hemispheres or the cerebellum. In conclusion, early suspicion of EBTB, proper investigations and adequate management is mandatory to decrease morbidity

Tuberculosis prevalence and BGG effeuicacy in bani-suef, Egypt

TB is a major problem in developing countries. This study was done on 3 stages; in stage 1, [October 1998], a number of 357 primary school children from rural areas classified into 3 groups, group A; 6-7 years before routine BCG vaccination at school entry, group B; 8-9 years, group C; 10-11 years. All these students have been tested both clinically, and by tuberculin testing. In stage 2, [January 1999] i.e. 3 months after routine BCG vaccination for group A, they have been tested again both clinically and by tuberculin. In stage 3, [October1999] ie. one year after the] evaluation of group C they have been tested again. The results were as follows:-In stage 1[st], no tuberculin positive cases in group A, 51.2% and 12.7% in group B and C respectively. In stage 2, 80.6% were tuberculin converters 3 months after BCG vaccination. In stage 3, 17.3% were tuberculin positive while 12.7% of the same group were positive in stage 1, i.e. 4.6% were tuberculin converters without BCG vaccination. Tuberculin sensitivity after BCG decreases with time and nearly vanishes after 5 years and the annual tuberculin conversion in this study was 4.6%. Tuberculin testing is highly recommended three months after vaccination and prevaccination to pupils vaccinated before and negative cases should be vaccinated again