[Harlequin's foetus]

We repport six cases of harlequin foetus. Clinical foetal appearance is typical. The evolution is signalled by foetal death. Antenatal using skin biopsy is possible after 19 weeks of amenorrhoea

L'association charge: a propos de 4 cas

We describe 4 cases of Charge association ranging in gestational age from 36 to 41 weeks. One was un stillborn, two died at birth. They had all less for elements of the classically defined association. Another anomalies were present in all the cases. The clinical foetapathological and therapy findings were studied the literature was reviewed with regard to the frequency of various malformations in this association

L'hypoplasie renale a propos de 10 cas

The autopsy contribute in the discovery of some congenital malformation that may be unnotied at the clinical examination of still-born and children died during the neonatal period. We report the case of kidney hypoplasia that was identified in 1,2% of the autopsied children in the laboratory and 9,7% of children with nephro-urologic malformation. The kidney hypoplasia is bilateral in 7 cases out of 10. It is associated with congenital malformations leading to a JARCHO LEVID Syndrom in 2 cases, to a CHARGE association in 1 case, and to a ROBERTS syndrom in 1 case

Agenesie renale a propos de 9 cas

The authors report ten cases of kidney agenesis among ninety nophro-urological malformations identified during 3 years 1/2 in the Laboratory of pathologic-embryology. The agenesis is bilateral in seven cases, it is associated with urogenital and gastro-intestinal malformations in 68% of the cases, and with bone malformations in 62% of the cases. The authors analyse the embryo-pathogenic aspects and insist on the genetical transmission of this disease

L'adolescent diabetiqueTunisien

Results of transversal study about two groups of diabetic patients [30 adolescnet and 30 adult] were reported in adolescent, they noted that: insulin requirement were higher than in adult. Cetosic and infection episodes more frequent. Hypoglycemic episodes lesser. Microangiopathic complications more frequent. Diabetes of the bed balanced. Psychologic profile disturbed. The importance of double loading up: metabolic and psychologic are raised

Drugs and the embryo fetal development

The teratogenic effect of drugs has been known since the tragedy of thalidomide. This effect will depend on the embryofoetal development stage for it may lead to chromosomal abnormalities with death of the ovum, or to congenital malformations in the child. These accidents should urge doctors to be very careful when they prescribe drugs to a pregant woman