ABSTRACT
Our study on 106 cases of bone tumors aims at correlating the clinical, radiological and cytological findings of benign and malignant tumors of bone and evaluating the usefulness of percutaneous biopsy as a diagnostic tool in underdeveloped countries. Giant cell lesions were the most common benign tumor, 42 cases (84%) and giant cell tumor was the most common giant cell lesion in our study, 27 (64.3%). Round cell tumor appeared to be the most common malignant tumor of bone, 20 cases (35.7%). Osteosarcoma represented 15 cases (14.2%) of all bone tumors and 26.8% of all malignant bone tumors in our study. Final histopathological diagnosis was available only in 54 cases. Out of which 53 cases showed concordance with previous cytological diagnosis. Only a single case of chondrosarcoma was misdiagnosed as chondroma on FNAC (false negative). The sensitivity and specificity of FNAC was 96.0% and 100% respectively while positive predictive value and negative predictive values were 100% and 96.7% respectively. The diagnostic accuracy in our study was 98.1%.
ABSTRACT
Iron and zinc are essential micronutrients for human health. Deficiencies in these 2 nutrients remain a global problem, especially among women and children in developing countries. Many studies indicate the low zinc intakes among premenopausal women, and avoidance of meat intake is characterized as one of the main causes. However, it seems dietary zinc reduces iron biochemical indices including ferritin, Hct, Hb, MCV, Transferrin Saturation. This study is an analytical cross - sectional survey, and the sample concluded 170 premenopausal women, and was a subgroup of the population that was studied in [Evaluation of intervention methods to preventing of Iron deficiency Anemia Research]. The data on demographic and food consumption were gathered by related questionnaire. Serum zinc was measured by atomic absorption, and other iron related biochemical parameters were measured by their specific related kits. Data was analyzed by food processor 2 and SPSS windows 10. Mean of dietary intake of iron and zinc was 24.51 and 3.45 mg/day, respectively. Mean of dietary intake of iron and zinc was 24.51 and 3.45 mg/day, respectively. Mean of daily calori intake was 1708.55 Kcal among subjects. Serum zinc was significantly correlated with hematocrit and hemoglobin [P was 0.027 and 0.02 respectively]. Analysis of regression between serum zinc and dietary factors including calori, protein, iron, fiber, zinc, vitamin C also showed the significant correlation between serum zinc and dietary vitamin C [r= 0.30, p= 0.026]. Among the iron biochemical indices, hematocrit and hemoglobin were significantly correlated with dietary zinc [p was 0.03 and 0.02, respectively]. Mean of serum zinc was significantly different between anemic, and non anemic groups, but normal, anemic and iron deficient anemic groups did not show significantly difference about serum zinc. Our results indicated that mean of dietary zinc is lower than RDA among the women, and this is confirmed by the NHANESII results. At the other hand, the significant relationship between zinc and Hb, Hct, vitamin C would explain the role of vitamin C in enhancing their bioavailability