[The effect of hydroalcoholic extract of Nectaroscordum tripedale on liver and kidney functional parameters in streptozotocin-induced diabetic male rats]

Introduction: the reducing effects of some of tripedale family plants on blood glucose, lipids and enzymes have been reported. The aim of the present study was to assess the effects of the hydroalcoholic extract of Nectaroscordum tripedale on liver and kidney function in streptozotocin-induced diabetic rats

Materials and Methods: forty male rats were randomly divided into five groups [n=8 each]. Groups 1, 3 [normal control and diabetic control] received distilled water, group 2 received 50 mg/kg/day Nectaroscordum tripedale extract, and the groups 4 and 5 [treatment groups 1 and 2] received 50 and 100 mg/kg/day of the Nectaroscordum tripedale extract respectively for 21 consecutive days. Diabetes was induced by a single injection of streptozotocin in rats. At the end of the 21st day, blood samples were collected by heart puncture. Serum levels of ALP, AST, ALT, Alb, BUN, creatinine and urea were evaluated

Results: results showed that the hydroalcoholic extract of Nectaroscordum tripedale can increase the average body weight in the treatments groups. ALP, AST, ALT, BUN levels decreased, wherease level of albumin [Alb] increased in a dose-dependent manner at the end experimental period [P<0.05]

Conclusion: our results showed that the extract of Nectaroscordum tripedale improved liver and kidney function in a dose dependent manner in experimental conditions

case of gastric zygomycosis in a diabetic patient successfully treated with total gastrectomy

Zygomycosis is regarded as a rare fetal infection in diabetics and other immunocompromised patients. The usual manifestations of this infection are: rhinosinusitis, pansinusitis, rhino-orbital and rhinocerebral. Primary gastrointestinal [GI] zygomycosis is a rare disease with a high mortality rate. The stomach is the most common site involved in GI mucormycosis. There are few reported cases of GI zygomycosis in the literature. Here we report a case of a diabetic woman with abdominal pain secondary to gastric zygomycosis that successfully responded to surgical treatment

Surgical emergency room workload charecteristics: single center experience during one year

Having information on characteristics of work load of emergency surgical room in 3 working-shifts per day help to manage facilities and health care providers more efficiently. The aim of this study is to evaluate the workload pattern of 3 working-shifts of a day in Nemazee Hospital, southern Iran. The patients who were admitted in the surgical Emergency Room from April 2007 to May 2008 were enrolled including the patients' demographics, referral sources, the busiest working-shifts and the type of procedures performed in the Emergency Room. 33,837 emergency surgery referrals were recorded, of which 74.7% were male and 25.3% were female with a mean age of 30.8 +/- 20.1 years. The busiest working-shift of the day was between 8.00 PM and 8.00 AM, when 48.4% patients were admitted. 12.1% were admitted in the Emergency Room while 4.8% patients were admitted in the hospital wards and 5.6% underwent emergency surgery. 32.4% of them were discharged while 39.7% left the hospital with their own responsibility and 4.7% patients escaped from the hospital. The total number of the deaths during the study period was 0.7%. Our results showed that patients were mainly male teenagers and most of the accidents happened by motorbike during the busiest working-shift of the day from 8 PM to 8 AM. Therefore, it would be useful to persuade health system administrators to set up some educational programs to increase the awareness of families and teenagers regarding trauma and also to allocate more resources to shorten waiting lists