Homozygosity for the Mediterranean alpha-thalassemic deletion [hemoglobin Baits hydrops fetalis]

Hemoglobin Barts hydrops fetalis syndrome is the most severe and generally fatal clinical phenotype of alpha-thalassemia. We diagnosed a fetus at 23-weeks gestation with having hydrops fetalis, by ultrasound. At 32 weeks, intrauterine death was detected. Molecular studies revealed that the fetus had the hemoglobin Barts hydrops fetalis syndrome due to homozygosity for the Mediterranean alpha-thalassemia deletion. This clinical phenotype is generally rare in the Eastern Mediterranean, and this is the first report of this syndrome from Iraq. Techniques for molecular characterization became available only very recently in this country, in a diagnostic setting. Thus, the detection of further cases might be expected in future

Neonatal jaundice and glucose-6- phosphate dehydrogenase deficiency

One hundred new born males babies aged 7 days and above were included in this study. These were divided into two groups - Group I included G6PD normal subjects and Group II included G6PD deficient subjects. Total bilirubin and G6PD enzyme levels were done by commercially available kits. Results were analysed by using students t test and level of significance was done. A significant increase in total bilirubin level was observed in infants of G6PD deficiency, Erythrocyte G6PD level is significantly decreased in 06% of infants born with neonatal jaundice

Pharmacological evaluation of methanolic extracts of Semecarpus anacardium and Tinosp ora cordifolia for their analgesic activity

Seeds and stem from the two medicinal plants, Semecarpus anacardium and Tinospora cordifolia respectively were extracted in absolute methanol to determine their analgesic activity. The analgesic activity was assessed on intact mice by tail flick latency in tail immersion method. Acetylsalicylic acid 300 mg/kg was used as standard drug. Both plant extracts were given in the doses of 300, 500 and 1000 mg/kg. Control group received 0.9% NaCl [saline] solution. All the solutions were administered orally. Results showed that showed that none of the plants have analgesic activity

role of iodide in the formation of cold follicles in young and aged mice

Iodide was consider as an important and necessary for the formation of the cold and partly cold follicles in the young and aged mice. There are many theory and idea about the formation of these follicle-s, and also many idea about the transformation of cold and partly cold follicles into hot follicles. About all these explanation the iodide play an important role in these theories and in biological process of the formation of cold follicles in laboratory animals. So by this articles can explained such possible formation of cold follicles

Obstetric bony injuries in neonates

Over a period of one year, 16161 consecutive live births were examined. There were 106 cases of bony injuries detected at birth with an overall incidence of 6.56/1000 live births. 92% were clavicular fractures. The only identifiable factor was high weight: 51 weighed more than 4000 gm and 14 were large for gestational age [> 4500 gm]. Prophylaxis should include not only improved obstetric care but also measures for prevention of fetal macrosomia