ABSTRACT
Reported here is a case of pheochromocytoma arising from an accessory adrenal gland. This tumor did not have significant clinical symptoms related to pheochromocytoma. The chief complaint was intermittent left upper quadrant pain. Scintigraphy of the abdomen identified normal bilateral adrenal glands, and a 56×63 mm tumor, adjacent the distal part of pancreas. The resected tumor was located between pancreas and spleen and was composed of normal adrenalortical tissue and pheochromocytoma. Immunohistoche-mical staining of tumor for KI67, chromogranin A, NSE, S100 and AE1 was positive. Pheochromocytomas, arising from an accessory adrenal gland, may lack some of the typical characteristics of such tumors and have rarely been reported
Subject(s)
Humans , Female , Adrenal Gland Neoplasms , Tomography, X-Ray ComputedABSTRACT
Cancer is a major medical problem and one of the most causes of death. Considering the young population of Iran and the high rate of malignancies, cancer registry is necessary in order to plan strategies to control and detection of cancer. This study was done on all pathological reports in Shahid Beheshti and Yahyanejad hospitals in Babol during 1990 to 2002. Sex, age and affected organs were determined and the repeated cases were excluded. Then they were categorized in two age groups 15-50 years and over 50 years. Data were analyzed by SPSS and using T-test and [P<0.05] was considered significant. Findings: After removing pediatric cancers, there were 3746 cases. The mean age for all cancer cases was 57.43 +/- 8.99 year, for men was 60.12 +/- 8.89 and for women was 53.42 +/- 9.13 year. Females were more than males in first group and vice-versa in second group that were statistically significant. In both sexes, the most frequency was in 7th decade. There were 2245 cases in males with the three most common cancers being: Stomach [23.69%], esophagus [9.75%] and skin [9.3%] and 1501 cases observed in females with the three most common cancers being: Esophagus [12.99%], breast [12.45%] and stomach [12.25%]. Since gastric cancer in males and esophageal cancer in females were the most frequent malignancies in this study and it seems that there is a relationship between these cancers and dietary, environmental and infective agents, further epidemiological research is needed to establish screening programs, early detection and better treatment
ABSTRACT
The association of malignant neoplasms arising in seborrheic keratosis has been previously proved. This study reports two cases of malignant neoplasms arising in seborrheic keratosis. The first case was a 79-year-old female who presented with a black nodule, recently became larger on her scalp. Histological examination revealed an irritated seborrheic keratosis transformation to a basal cell carcinoma in its periphe j, extended the underlying dermis. The second one was a 76-year-old female with an ulcerated nodule arising in a pigmented lesion on her thigh. Histological examination of the nodule revealed squamous cell carcinoma arising in seborrheic keratosis. Both cases presented a rare development of malignant change in seborrheic keratosis. Recent growth, an ulceration or nodule formation are signs of malignant changes and these lesions should be biopsied and examined histologically
ABSTRACT
Tuberculosis [TB] is still one of the most common causes of death in the world. The incidence of TB, included extra pulmonary variant has been increasing in developed countries for two past decades and also has a high incidence and prevalence in underdeveloped countries. To determine the type of involved organ by extra pleuro-pulmonary TB in Shahid Beheshti Hospital in Babol, the present study was carried out. Pathological reports of extra pleuro-pulmonary TB in Shahid Beheshti Hospital during performed 1990-2003 have been studied. Sex, age and involved organs were determined, and subsequently the appropriate table was set up. During 14 years, we diagnosed 82 cases of extra pleuro-pulmonary TB, 44 were men and 38 women, with age ranges of 8 months - 79 years. TB lymphadenitis was the most common form [45cases], followed by soft tissue 14 cases, bone 4, intestine 3, and 2 cases for endometrium, skin, testis and epididymis, and one case for ovary, tonsil, larynx, prostate, parotid gland, synovium, stomach, and kidney. The diagnosis was confirmed by presence of acid-fast bacillus in tissue section by Ziehl Neelsen staining and good response to anti TB treatment. Although the TB lymphadenitis was the most common type, but in regions with high rate of TB, considering extra pleuro-pulmonary TB in unusual clinical setting is important and using appropriate diagnostic procedures and treatment if it is necessary
Subject(s)
Humans , Female , Male , Tuberculosis, Pulmonary , Tuberculosis, Pleural , Tuberculosis, Lymph NodeABSTRACT
Background: Acute respiratory tract infections cause 4.5 million childhood deaths all over the world. Most of these deaths occur in the developing countries. Both bacterial and viral pathogens arc responsible for these deaths. Adenovirus respiratory tract infections are spread over the entire world, but the fatal disease is rarely seen
Methods: This descriptive case-series study has been conducted from October 2003 to September 2004 on 96 children of up to 5 year old. The relative frequency of adenovirus respiratory tract infection was studied. For this purpose, the nasopharyngeal secretions were obtained to detect adenovirus by Immmofluorescent Antibody [IFA] method. Seasonal incidence age distribution, and clinical signs and symptoms of this infection were studied
Findings: The relative frequency of Adenovirus respiratory infection was 10.4%. Most commonly it occurs in children aged less than 1 year and in autumn. In addition, cough and rhinorrhea are the most common signs [90%] and fever is the most common symptom [100%] in our patients. Similarly, pneumonia was the most common [40%] clinical manifestation in our patients
Conclusion: According to above data, the frequency of Adenoviurs infection and the common age for infection in this study are similar to other studies but pneumonia is the common illness which can be explained by the fact that this hospital is a referral center for these patients
ABSTRACT
Background and Objective: Hirschsprung's disease [H.D] is the most common cause of lower gastrointestinal tract obstruction in newborns. Diagnosis of H.D was established by a full-thickness rectal biopsy, then it was replaced by rectal suction biopsy, that is easier and has less complications. This study was done to compare the submucosal and muscular coat of rectal wall for ganglion cells
Methods: In this descriptive, analytical and cross-sectional study, data were obtained from 239 pathological reports in archive of Shahid Beheshti hospital, department of pathology from 1991 to 2001. Serial sections [Up to 60 sections] were tested microscopically
Findings: Sixty-one from 239 specimens were diagnosed as H.D [19.3%] and in 172 cases ganglion cells were present in both muscular and submucosal layers [54.43%]. Sensitivity of submucosal for presence of ganglion cells was 96.6% and correlation between submucosal and muscular layers for absence of ganglion cell was 100% [P<0.05]
Conclusion: The results showed a good correlation between advantages of serial sections of muscular and submucosal layers for presence of ganglion cells. Probability of coincident presence of ganglion cells in both layers was confirmed
ABSTRACT
Background and Objective: Bronchoalveolar lavage [BAL] cytology is an important widely used clinical procedure to diagnosis of lung diseases. Since histologic examination of bronchial biopsy is definite method in diagnosis of malignancy, this study was done to evaluate sensitivity and specificity of BAL cytology in comparison with bronchial biopsy
Methods: To determine its value in diagnosis of lung cancer, it was reviewed 348 samples [BAL cytology combined with bronchial biopsy] from 331 patients over period of 12 years, in pathology department of Shahid Beheshti hospital in Babol
Findings: One hundred and fourteen malignant cases were isolated from 331 patients. Of these cases. 57 were determined by both methods, 39 cases in biopsy samples alone, and 18 cases only by BAL cytology
Conclusion: The sensitivity and specifity for BAL cytology were 60% and 92%, respectively that is valuable and reproducible in comparison with the other studies