Evaluation of antimicrobial resistance of Acinetobacter baumannii to imipenem, ciporofloxacin and ceftazidime using E test

Resistance patterns among nosocomial bacterial pathogens in hospitals may vary widely from country to country at any given point and within the same country over time. Acinetobacter baumannii is one of the most important bacterium causes hospital acquired infections. Therefore, surveillance of antibiotic resistance of A. baumannii is necessary, especially in our country which there is no have much data in this field. In a prospective study, strain comprised of a total of 191 recent clinical isolates selected consecutively from clinical infections of separate patients from three University hospitals in Tehran. Minimum inhibitory concentration [MIC] of these organisms for imipenem, ciprofloxacin and ceftazidime was determined using E test method according to CLSI guideline. Also, MIC50 and MIC90 percent was calculated for each of these antibiotics. The percentages of Acinetobacter baumannii isolates susceptible to ciprofloxacin and ceftazidime by E test were 55.5% and 44.5%, respectively. The percentage of bacterium susceptible to imipenem by E test was 72.8%. MIC50 and MIC90 of imipenem in E test were 1.5 and > 32, respectively. High antimicrobial resistance against A. baumannii species has been seen in Iran; therefore, it is necessary to implement some approaches for prevention of bacterial spread

Evaluation of the 10th External Quality Assessment Scheme results in clinical microbiology laboratories in Tehran and districts

We evaluated the performance of microbiology laboratories in the 10th run of the external quality assessment scheme [EQAS] in Tehran and districts. Each laboratory was sent 2 species of bacteria for identification. Of the 487 laboratories that participated, 437 returned their findings. While 77.0% and 69.9% correctly identified Staphylococcus saprophyticus and Citrobacter freundii respectively, only 29.8% correctly identified Acinetobacter baumanii, 25.3% identified Enterococcus faecalis and 35.6% identified Enterobacter agglomerans. However 78.7% and 79.5% of the laboratories reported correct -results for susceptibility testing for S. saprophyticus and C. freundii respectively